Identification
BMDB Protein ID BMDBP02360
Secondary Accession Numbers None
Name Biliverdin reductase A
Synonyms Not Available
Gene Name BLVRA
Protein Type Enzyme
Biological Properties
General Function Involved in biliverdin reductase activity
Specific Function Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
Pathways
  • Porphyrin Metabolism
  • Porphyrin-containing compound metabolism
  • Protoheme degradation
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 4
Locus Not Available
SNPs BLVRA
Gene Sequence
>891 bp
ATGAACACAGAGCCCGAGAGGAAGTTTGGCGTGGTGGTGGTGGGCGTCGGCAGAGCCGGC
TCCGTACGGATGCGGGACCTGCGGAATCCACACGCTTCCTCAGCGTTCCTGAACCTGATT
GGCTTCGTGTCCAGACGAGAGCTGGGGAGCATTGATGAGGTGCCGCAAATTTCTCTGGAA
GATGCTCTTTCCAGTCAAGAGGTCGAGGTTGCTTTTATCTGCAGTGAGAGCTCCAGCCAC
GAGGACTACATCAGGCAATTCCTGAATGCTGGAAAGCATGTCCTTGTGGAATACCCCATG
ACACTGTCTTGGGTGGCAGCTAAGGACCTGTGGGAGTTGGCCGAGCAGAAAGGGAAAGTC
TTGCATGAGGAGCATGTTGAACTCTTGATGGAGGAGTTTGCATTCCTGAAGAAAGAAGTG
GTGGGGAAGGACCTGCTGAAAGGGTCTCTCCTCTTCACAGCTGCCCCATTGGAAGAAGAG
CGGTTTGGCTTCCCTGCGTTCAGCGGCATCTCTCGCCTGACCTGGCTGGTCTCCCTCTTC
GGGGAGCTTTCTCTCGTATCTGCCACTTTGGAAGAGCGAAAGGAAGACCAGTATATGAAG
ATGACCGTGTGCTTGGAGACAGAGAACAAAAGCCCGCTGACCTGGATTGAAGAGAAAGCA
CCTGGCCTAAAGCGAAACAGACGCTTAAGCTTCCATTTCAGATCTGGGTCCCTAGAGAAT
ATGCCCAACGTAGGCATCAATAAGAATATTTTCCTGAAAGATCAGAATATATTTGTCCAG
AAACTCCTGGGCCAGTTCTCGGAAGAGGAGCTGGCTGCCGAGAAGAAACGCATCCTGCAC
TGCCTGTGGCTCGCAGGAGAGATCCAGAAACACTGCTGCTCAAAGCAGTGA
Protein Properties
Number of Residues 296
Molecular Weight 33644.0
Theoretical pI 6.12
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 225-245
  • 253-273
  • 281-301
  • 320-340
  • 361-381
  • 383-403
  • 417-437
  • 450-470
Protein Sequence
>BLVRA protein
MNTEPERKFGVVVVGVGRAGSVRMRDLRNPHASSAFLNLIGFVSRRELGSIDEVPQISLE
DALSSQEVEVAFICSESSSHEDYIRQFLNAGKHVLVEYPMTLSWVAAKDLWELAEQKGKV
LHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAAPLEEERFGFPAFSGISRLTWLVSLF
GELSLVSATLEERKEDQYMKMTVCLETENKSPLTWIEEKAPGLKRNRRLSFHFRSGSLEN
MPNVGINKNIFLKDQNIFVQKLLGQFSEEELAAEKKRILHCLWLAGEIQKHCCSKQ
GenBank ID Protein AAI40587.1
UniProtKB/Swiss-Prot ID A5D7K0
UniProtKB/Swiss-Prot Entry Name A5D7K0_BOVIN
PDB IDs Not Available
GenBank Gene ID BC140586
GeneCard ID BLVRA
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available