| Identification |
|---|
| BMDB Protein ID
| BMDBP02507 |
| Secondary Accession Numbers
| None |
| Name
| E3 ubiquitin-protein ligase CBL |
| Synonyms
|
Not Available
|
| Gene Name
| CBLC |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 18 |
| Locus
| Not Available |
| SNPs
| CBLC |
| Gene Sequence
|
>1476 bp
ATGGCTGCGGCGGCCCTGCGGGGACGACAGTGGGGAGAATCCCGCGCGTTCGGCCGCGCA
GTGAGGCTGCTGCAGCGCCTGGAAGAACAATGCGGGGACCCCCGGCTCTCCTCGAGTCCC
CCCTCCCTTCGGGACCTGCTGCCCCGCACGGCGCAGCTGCTGCGCCAAGTGGCGCAAGCC
CGGCGGGAGGCCGGCGGAGGCGTCCCCGAGGGTCCCGGGGGGCCGTGGGACTTTCTGATG
GTCTATCTGGCTAACCTGGAGGCCAAGAGCAGGCAGGTGGCGGCGCTGCTGCCACCCCAC
GGCCGAAAGATCGCCAACGACGAGCTCTTCCGGGAGGGCTCCAGACTCAGGCGGCAACTG
GCCAAGCTGGCCCTCATCTTCAGCTATATGCACGCGGAGCTGGATGCGCTCTTCCCCGGC
GGCAGGTACTGCGGCCACACCTACCAGCTCACCAAGGTCTCCGCCCACACTTTCTGGAGG
GAGCGCTGCGGAGCCCGATGTGTGCTGCCCTGGGCTGAGTTTGAGGCGGTCTTATGCATC
TGCCACCCTGTGGAGCCAGGCTCCACGGCCCTGGCCTTGCGCTCCACCATCGACCTCACC
TGCAGCGGCCACGTGTCCATCTTCGAGTTTGACATCTTCACCAGGCTCTTCCAGCCGTGG
CCAACACTCCTCAAGAACTGGCAGCTCTTGGCGGTCAACCACCCGGGTTACATGGCCTTC
CTCACATACGATGAGGTCCAAGCCCGTCTGCAGACTTTCAGAGACAAGCCAGGCAGCTAC
ATCTTCCGGCCCAGCTGCACTCGCCTGGGGAAGTGGGCCATCGGATACGTGAGCTCAGAC
GGCAGCATCTTGCAGACCATCCCTCTCAACAAACCCCTGTTCCAGGTGCTCCTGGAAGGA
CAGAAGGAAGGCTTCTACCTCTACCCAGATGGGAAGAACCACAACCCGGACCTGACCGAA
CTCTGCCACATGGAACCGCATCAGCACATCCACGTGTCGGAGGAGCAGCTGCAGCTCTAC
TGGGCCATGGACTCTACGTTTGAGCTCTGCAAGATCTGTGCCGAGAGCAACAAGGACGTG
AAGATAGAGCCCTGCGGGCACCTGCTCTGTAGCCGCTGCCTGGCTGCCTGGCTGTGCTCA
GACAGCCAGACCTGCCCCTTCTGCCGCTGCGAGATCAAGGGCCAAGAGGCTGTGAGTATC
CATCAGTTCCACGTCAGTGCCACTGTGGAGGACCCAGAGCACAGCAGTGATGAGGAGGAG
CTGGAGCAGATGGCCCCTTCAGGTCCTCCCCTGCCCCCTCGGCTGGATCTGTGTCCCAAG
AGCCCCAGCAGCAAAGGCCACCTGAACGTGGCACCTCCGACCCTTCCCAGACTTCGAGCT
CCTCTTCCCTTGCCAAGATTCTGGACTGCGGCTTCAGCCCCGTGGGAAGTCACCTCCAGT
CCCCAGGCCAGGGAGGGAGCCCGAGGAAACTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 491 |
| Molecular Weight
| 54955.0 |
| Theoretical pI
| 7.46 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>CBLC protein
MAAAALRGRQWGESRAFGRAVRLLQRLEEQCGDPRLSSSPPSLRDLLPRTAQLLRQVAQA
RREAGGGVPEGPGGPWDFLMVYLANLEAKSRQVAALLPPHGRKIANDELFREGSRLRRQL
AKLALIFSYMHAELDALFPGGRYCGHTYQLTKVSAHTFWRERCGARCVLPWAEFEAVLCI
CHPVEPGSTALALRSTIDLTCSGHVSIFEFDIFTRLFQPWPTLLKNWQLLAVNHPGYMAF
LTYDEVQARLQTFRDKPGSYIFRPSCTRLGKWAIGYVSSDGSILQTIPLNKPLFQVLLEG
QKEGFYLYPDGKNHNPDLTELCHMEPHQHIHVSEEQLQLYWAMDSTFELCKICAESNKDV
KIEPCGHLLCSRCLAAWLCSDSQTCPFCRCEIKGQEAVSIHQFHVSATVEDPEHSSDEEE
LEQMAPSGPPLPPRLDLCPKSPSSKGHLNVAPPTLPRLRAPLPLPRFWTAASAPWEVTSS
PQAREGARGNS
|
| External Links |
|---|
| GenBank ID Protein
| AAI49568.1 |
| UniProtKB/Swiss-Prot ID
| A6QPZ5 |
| UniProtKB/Swiss-Prot Entry Name
| A6QPZ5_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC149567 |
| GeneCard ID
| CBLC |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
