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Showing Protein Arachidonate 5-lipoxygenase-activating protein (BMDBP02546)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02546 |
| Secondary Accession Numbers | None |
| Name | Arachidonate 5-lipoxygenase-activating protein |
| Synonyms | Not Available |
| Gene Name | ALOX5AP |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in arachidonic acid binding |
| Specific Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 12 |
| Locus | Not Available |
| SNPs | ALOX5AP |
| Gene Sequence |
>486 bp ATGGACCAAGAAGCCGTGGGCAATATCGTCCTGCTGGCCATTGTTACCCTCATCAGTGTG GTCCAGAATGGGTTCTTTGCCCACAAGGTGGAGCACGAAAGCAAGACCCACAATGGGCGG AGCTTCCAGAGGACTGGGACGCTGGCCTTTGAGCGGGTCTACACTGCCAACCAGAACTGT GTGGATGCCTACCCCACCTTCCTCGTCATGCTCTGGAGCGCCGGGCTTCTCTGCAGCCAA GTTCCTGCTGCCTTTGCTGGGCTGATGTACCTGTTCGTGAGGCAGAAGTACTTTGTCGGC TACCTCGGGGAGAGAACTCAGAGCACGCCTGGTTACATATTTGGGAAACGCATTATCCTG TTCCTATTTGCCATGTCCCTCGCTGGGATACTCAACTATTTCTTCATCGCCCTTTTCGGA AGTGACTTTGAAAACTACATCAAGACCGTCACTACCACCATCTCCCCTCTCCTTCTCATC CCTTGA |
| Protein Properties | |
| Number of Residues | 161 |
| Molecular Weight | 18028.0 |
| Theoretical pI | 8.66 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Arachidonate 5-lipoxygenase-activating protein MDQEAVGNIVLLAIVTLISVVQNGFFAHKVEHESKTHNGRSFQRTGTLAFERVYTANQNC VDAYPTFLVMLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL FLFAMSLAGILNYFFIALFGSDFENYIKTVTTTISPLLLIP |
| External Links | |
| GenBank ID Protein | AAI18390.1 |
| UniProtKB/Swiss-Prot ID | Q148F2 |
| UniProtKB/Swiss-Prot Entry Name | AL5AP_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC118389 |
| GeneCard ID | ALOX5AP |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |