Identification
BMDB Protein ID BMDBP02566
Secondary Accession Numbers None
Name Malic enzyme
Synonyms Not Available
Gene Name ME1
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Not Available
Pathways
  • LPS and Citrate Signaling and Inflammation
  • Pyruvate Metabolism
  • Transfer of Acetyl Groups into Mitochondria
Reactions
NADP + L-Malic acid → NADPH + Hydrogen + Carbon dioxide + Pyruvic acid details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 9
Locus Not Available
SNPs ME1
Gene Sequence
>1707 bp
ATGGGCACCAGCTGTGTGGATAGCACGTGGAGCAAAGCCAGGCGTGGTCATGGTAGGGCC
AGACCCAGAGACTTGGCTTTTACCCTGGAAGAGAGGCAGCAACTGAACATTCATGGCCTG
TTGCCACCCTCCTTCATCAGTCAGGATGTCCAGGTCCTTCGAGTACTTAAGAATTTTGAG
CGTCTGAACTCTGATTTTGACAGGTATCTTCTCTTAATGGATCTTCAAGATAGAAACGAA
AAGCTCTTCTATAAAGTGCTGATGTCTGACATTGAGAAATTCATGCCTATCGTTTATACT
CCCACTGTGGGTCTAGCTTGCCAACAATATAGTTTAGCATTTCGGAAGCCAAGAGGTCTC
TTTATTAGTATCCATGATCGAGGACATATTTCTTCTGTTCTTAATGCATGGCCAGAAGAT
GTCATCAAGGCTATTGTGGTGACTGATGGAGAACGTATTCTTGGCTTGGGAGACCTTGGC
TGTAATGGGATGGGCATCCCCGTGGGTAAACTGGCTCTGTATACAGCTTGTGGAGGGATG
AACCCTCAACAGTGTTTGCCTGTCATGCTGGATGTGGGAACTGAAAATGAGGAGTTACTT
AAAGATCCATTGTACATTGGACTACGGCAGAGAAGAGTAAGAGGTCCTGAATATGATGAT
TTTTTGGATGAATTCATGGAGGCAGTTTCTCTCAAGTATGGCATGAACTGCCTTATTCAG
TTTGAAGATTTTGCCAATATAAATGCATTTCGGCTCCTGAGAAAGTATCAAAACCAGTAT
TGCACATTCAATGATGATATCCAAGGAACAGCATCTGTTGCAGTTGCCGGCATCCTTGCA
GCCCTTCGAATAACCAAGAACAAGCTGTCTGAGCAAACAGTTCTATTCCAAGGAGCTGGA
GAGGCTGCCTTAGGGATTGCACACCTGATTGTCATGGCCATGGAGAAAGAAGGTTTATCA
AAGGAGCAAGCCATAGAGAAGATATGGTTGGTTGACTCGAAAGGATTAATAGTTAAGGGA
CGTGCTGCCTTAACACAAGAGATAGAGGAATTTGCCCATGAACATAAAGAAATGAAGAAC
CTTGAAGCCATCGTTCAAGATATAAAACCAACTGCCCTCATTGGAGTTGCTGCGATTGGT
GGTGCGTTCTCAGAACAAATTATCAAAGACATGGCAGCCTTCAATGAACGGCCTATTATT
TTTGCCTTGAGTAATCCAACTAGTAAAGCAGAATGTACTGCAGAGCAGTGCTATAAACTG
ACCAAGGGTCGCGCCATTTTTGCCAGCGGCAGTCCTTTTGATCCCGTTACCCTTCCGAGT
GGAAAGTCTCTTTATCCTGGCCAAGGCAACAATTCCTACGTGTTCCCTGGAGTTGCTCTT
GGTGTTGTGGCGTGTGGACTGAGGCATATCACGGATAAGATTTTTCTCACCACTGCTGAG
GTCATAGCTCAGCAAGTATCAGATAAACACTTGGAGGAGGGCCGGCTTTATCCTCCTTTG
GACACCATTAGAGATGTTTCTCTGAAAATTGCAGAAAAGATTGTGAAAGATGCATACCAA
GAAAAGACAGCCACAGTTTATCCTGAACCCCCAAACAAGGAAGCATTTGTCCGCTCTCAG
ATGTATAGCACTGACTATGACCAGATTCTACCTGATTGTTATCCTTGGCCTAAAGAGGCC
CAGAAAATACAGACCAAACTTGACTAG
Protein Properties
Number of Residues 568
Molecular Weight 63372.0
Theoretical pI 6.1
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Malic enzyme
MGTSCVDSTWSKARRGHGRARPRDLAFTLEERQQLNIHGLLPPSFISQDVQVLRVLKNFE
RLNSDFDRYLLLMDLQDRNEKLFYKVLMSDIEKFMPIVYTPTVGLACQQYSLAFRKPRGL
FISIHDRGHISSVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGM
NPQQCLPVMLDVGTENEELLKDPLYIGLRQRRVRGPEYDDFLDEFMEAVSLKYGMNCLIQ
FEDFANINAFRLLRKYQNQYCTFNDDIQGTASVAVAGILAALRITKNKLSEQTVLFQGAG
EAALGIAHLIVMAMEKEGLSKEQAIEKIWLVDSKGLIVKGRAALTQEIEEFAHEHKEMKN
LEAIVQDIKPTALIGVAAIGGAFSEQIIKDMAAFNERPIIFALSNPTSKAECTAEQCYKL
TKGRAIFASGSPFDPVTLPSGKSLYPGQGNNSYVFPGVALGVVACGLRHITDKIFLTTAE
VIAQQVSDKHLEEGRLYPPLDTIRDVSLKIAEKIVKDAYQEKTATVYPEPPNKEAFVRSQ
MYSTDYDQILPDCYPWPKEAQKIQTKLD
GenBank ID Protein ACL37012.1
UniProtKB/Swiss-Prot ID B8YB77
UniProtKB/Swiss-Prot Entry Name B8YB77_BOVIN
PDB IDs Not Available
GenBank Gene ID FJ515745
GeneCard ID ME1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available