Showing Protein Beta-1 adrenergic receptor (BMDBP02579)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 metabolites
Identification
BMDB Protein ID BMDBP02579
Secondary Accession Numbers None
Name Beta-1 adrenergic receptor
Synonyms Not Available
Gene Name ADRB1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 26
Locus Not Available
SNPs ADRB1
Gene Sequence Not Available
Protein Properties
Number of Residues 467
Molecular Weight 50137.0
Theoretical pI 7.96
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 56-84
  • 94-120
  • 133-154
  • 173-196
  • 223-248
  • 307-336
  • 342-364
Protein Sequence 
>Beta-1 adrenergic receptor
MGAGVLALGASEPCNLSSAAPVPDGAATAARLLVPASPPASLLTSASEGPPLPSQQWTAG
MGLLMAFIVLLIVVGNVLVLVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVC
TVWAISALVSFLPIFMQWWGDKDAKASRCYNDPECCDFIINEGYAITSSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLSGPARLPSPAPSPGPPLPAATVANGRANKRRPPR
LVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFN
PIIYCRSPDFRKAFQRLLCCARRAACGSHAAAGDPPRALGCLAVARPSPSPGAASDDDDD
DDEDDVGAAPPVRLLEPWAGYNGGAAANSDSSPDEPSRAGCASESKV
GenBank ID Protein AAF21435.1
UniProtKB/Swiss-Prot ID Q9TT96
UniProtKB/Swiss-Prot Entry Name ADRB1_BOVIN
PDB IDs Not Available
GenBank Gene ID AF188187
GeneCard ID ADRB1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available