Showing Protein GDNF family receptor alpha-2 (BMDBP02587)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02587 |
| Secondary Accession Numbers | None |
| Name | GDNF family receptor alpha-2 |
| Synonyms | Not Available |
| Gene Name | GFRA2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in receptor activity |
| Specific Function | Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 8 |
| Locus | Not Available |
| SNPs | GFRA2 |
| Gene Sequence |
>1395 bp ATGATCTTGGCAAACGCCTTCTGCCTCTTCTTCTTTTTAGACGAGACCCTCCGCTCTTTG GCCAGCCCTTCCTCCCCGCAGGGCCCCGAGCTCCACGGCTGGCGCCCCCCAGTGGACTGT GTCCGGGCCAATGAGCTGTGCGCGGCCGAATCCAACTGCAGCTCCCGCTACCGCACGCTG CGCCAGTGCCTGGCCGGCCGGGACCGCAACACTATGCTGGCCAACAAGGAGTGCCAGGCA GCCCTGGAGGTGCTGCAGGAGAGCCCGCTCTACGACTGCCGCTGCAAGCGGGGCATGAAG AAGGAGCTGCAGTGCTTGCAGATCTACTGGAGCATCCACCTGGGGCTGACCGAGGGCGAG GAGTTTTATGAAGCCTCACCTTATGAGCCAGTGACCGCCCGCCTCTCGGACATCTTCAGG CTTGCTTCAATCTTCTCAGGGACAGGGGCAGACCCGGCGGTCAGCACCAAGAGCAACCAC TGCCTGGATGCCGCCAAGGCCTGTAACCTGAACGATAACTGCAAGAAGCTGCGCTCCTCC TACATCTCCATCTGCAACCGTGAGATCTCGCCCACGGAGCGCTGCAATCGCCGCAAGTGC CACAAGGCCCTGCGCCAGTTCTTTGACCGCGTACCCAGCGAGTACACCTACCGCATGCTC TTCTGCTCCTGTCAGGACCAGGCGTGCGCCGAGCGCCGCCGCCAGACCATCCTGCCCAGC TGCTCCTACGAGGACAAGGAGAAGCCCAACTGCCTGGACCTCCGCAGCCTGTGCCGGACA GACCACCTGTGCAGGTCCCGCCTGGCGGACTTCCATGCCAACTGCCGTGCCTCCTACCAG ACGCTCACCAGCTGCCCCACCGACAATTACCAAGCGTGTCTGGGCTCCTACGCTGGCATG ATCGGGTTTGATATAACACCCAACTACGTGGACTCCAGCCCCACGGGCATCGTGGTGTCC CCCTGGTGCAGCTGTCGTGGGAGTGGAAACATGGAGGAAGAGTGTGAGAAGTTTCTGAAG GATTTCACAGAGAACCCATGCCTCCGGAATGCCATCCAGGCCTTTGGCAATGGTACAGAT GTGAACCTGTCCCCTAAAAGCCCCCCATTCCAGGCCACACAGGCCCCTCGGGTAGACAAA ACGCCTTCGTTGCCAGATGACCTCAGTGATAGCACCAGCCTGGGGACCAGTGTCATCAGT ACCTGCACATCTGTCCAGGATCAGGGGCTGAAGGCCAATAACTCCAAAGAGTTAAGCATG TGCTTCACAGAGCTCACAACCAATATCATCCCAGGGAGTAAAAGGGTGATCAAACCTAAC TCAGGCCCCCGCAGAACCAGACCGTCGGCTGCCTTGACTGCTGCATCCTTCCTGATGCTG AAGCTGGCCTTGTAG |
| Protein Properties | |
| Number of Residues | 464 |
| Molecular Weight | 51659.0 |
| Theoretical pI | 7.88 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>GDNF family receptor alpha-2 MILANAFCLFFFLDETLRSLASPSSPQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE EFYEASPYEPVTARLSDIFRLASIFSGTGADPAVSTKSNHCLDAAKACNLNDNCKKLRSS YISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPS CSYEDKEKPNCLDLRSLCRTDHLCRSRLADFHANCRASYQTLTSCPTDNYQACLGSYAGM IGFDITPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLKDFTENPCLRNAIQAFGNGTD VNLSPKSPPFQATQAPRVDKTPSLPDDLSDSTSLGTSVISTCTSVQDQGLKANNSKELSM CFTELTTNIIPGSKRVIKPNSGPRRTRPSAALTAASFLMLKLAL |
| External Links | |
| GenBank ID Protein | AAX08817.1 |
| UniProtKB/Swiss-Prot ID | Q5E9X0 |
| UniProtKB/Swiss-Prot Entry Name | GFRA2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BT020800 |
| GeneCard ID | GFRA2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |