| Identification |
|---|
| BMDB Protein ID
| BMDBP02591 |
| Secondary Accession Numbers
| None |
| Name
| Glucocorticoid modulatory element-binding protein 1 |
| Synonyms
|
Not Available
|
| Gene Name
| GMEB1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| Not Available |
| SNPs
| GMEB1 |
| Gene Sequence
|
>1692 bp
ATGGCTAATGCAGAAGTGAGTGTCCCAGTGGGAGATGTGGTTGTGGTACCCACTGAAGGA
AATGAAGGGGAGAACCCTGAAGACACTAAAACCCAAGTGATCTTGCAGTTACAGCCTGTG
CAACAAGGGATTTATGAAGCTGGATCTGAGAACAATACGGCAGTTGTGGCAGTAGAAACT
CACACAATACACAAAATTGAAGAAGGGATTGATGCAAGCACTATAGAAGCAAATGAGGAT
ATGGAAATTGCTTACCCCATAACTTGTGGGGAGAGCAAAGCCATTCTCCTTTGGAAGAAG
TTTGTATGTCCAGGAATAAATGTAAAGTGTGTCAAGTTCAATGATCAGTTGATCAGCCCC
AAGCATTTTGTTCATCTGGCTGGCAAATCCACCTTGAAGGACTGGAAGAGAGCTATTCGT
CTGGGTGGAATCATGCTCAGGAAAATGATGGACTCCGGACAGATTGATTTTTACCAACAT
GACAAGGTTTGCTCCAATACCTGCAGAAGCACCAAATTTGATCTTCTTATCAGCAGTGCG
AGAGCTCCAGTGCCAGGACAGCAGACAAGTGTGGTGCAGACGCCCACATCGGCCGATGGT
AGCATCACACAGATTGCCATCTCAGAAGAGAGCATGGAAGAGGCAGGGCTGGAATGGAAC
TCGGCTCTCACTGCTGCTGTCACCATGGCCACAGAGGAGGGCGTGAAGAAAGACTCAGAG
GAAATTTCACAGGACACTTTGATGTTCTGGAAAGGAATAGCTGATGTTGGACTGATGGAA
GAGGTTGTCTGCAATATACAGAAGGAAATAGAGGAGCTACTTAGGGGAGTTCAGCAGCGG
CTCATCCAGGCTCCCTTCCAGGTCACAGATGCTGCTGTTCTTAACAATGTAGCACATACA
TTTGGCCTAATGGACACAGTTAAGAAGGTTTTGGACAACAGGAAGAACCAAGTAGAACAG
GGAGAAGAGCAGTTTCTCTATACTCTCACAGACTTGGAACGCCAGTTGGAAGAACAGAAG
AAGCAAGCCCAGGATCACAGGCTGAAATCCCAGACAGTTCAAAATGTGGTACTGATGCCT
GTGAGCACTCCTAAGCCTCCCAAAAGGCCCCGGCTCCAGCGGCCAGCCTCCACCACCGTC
CTGAGCCCTTCTCCTCCTGTCCACCAGCCTCAGTTCACGGTCATCTCACCCATCACCATC
ACACCAGTGGGTCAGTCATTTTCCATGGGCAATATTCCAGTGGCCACCCTCAGCCAGGGC
TCCAGTCCTGTGACTGTCCACACACTGCCTTCTGGCCCTCAGCTCTTCCGTTATGCCACA
GTGGTCTCCTCAGCCAAGAGCAGCTCACCAGACACAGTGACCATCCACCCTTCGTCTAGC
TTGGCACTGCTGAGCTCCACCGCCATGCAGGATGGGAGTACCCTGGGCAACATGACCACC
ATGGTGAGCCCTGTGGAGCTGGTGGCCATGGAGTCTGGCCTAACCTCGGCCATCCAGGCA
GTTGAAAGCACCTCAGAGGATGGGCAGACCATCATTGAGATTGACCCAGCCCCAGACCCA
GAGGCCGAGGATACTGAGGGCAAAGCAGTCATTTTGGAGACCGAACTGAGGACTGAGGAG
AAAGTCGTGGCTGAGATGGAAGAACACCAGCATCAAGTCCACAATGTGGAGATTGTGGTC
TTAGAAGATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 563 |
| Molecular Weight
| 61321.0 |
| Theoretical pI
| 4.49 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glucocorticoid modulatory element-binding protein 1
MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENNTAVVAVET
HTIHKIEEGIDASTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISP
KHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSA
RAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSE
EISQDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHT
FGLMDTVKKVLDNRKNQVEQGEEQFLYTLTDLERQLEEQKKQAQDHRLKSQTVQNVVLMP
VSTPKPPKRPRLQRPASTTVLSPSPPVHQPQFTVISPITITPVGQSFSMGNIPVATLSQG
SSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTT
MVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEE
KVVAEMEEHQHQVHNVEIVVLED
|
| External Links |
|---|
| GenBank ID Protein
| AAI13253.1 |
| UniProtKB/Swiss-Prot ID
| Q2HJ87 |
| UniProtKB/Swiss-Prot Entry Name
| GMEB1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC113252 |
| GeneCard ID
| GMEB1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
