Identification
BMDB Protein ID BMDBP02592
Secondary Accession Numbers None
Name Interferon alpha/beta receptor 2
Synonyms Not Available
Gene Name IFNAR2
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 1
Locus Not Available
SNPs IFNAR2
Gene Sequence
>1593 bp
ATGCTTTTGAGCCAGAATGTGTCAGCGATTGGACCACTGAATTTGTATCCCATGGTGCAC
ATCAGCCTCGTGTTTGGTATTTCGTATGTTGCGCCTGTTCTTTCAGATGAACATTGCACT
TTAAAGATGAGATTCCGAAATTTCCAGTCAGTCTTATCATGGGAATTAAAAAACCATTCA
ATTGTACCAACTCACTATACATTATGGTACACAATCATGAGTAAACGAGAAGATATGAAG
GTCGTCAAGGACTGTATAAACGTCACAAGATCGTTTTGTGACCTCACAGACGTGTGGGTA
AACACGACGGACATGTACATCCCCCAGGTGGTTGGATTCAGAGAGAATGCAAAGCTGGTC
ATTTGTATGGGCTCTTTCTTCCTGGTGCCAGACAAGCCTTTGGACCCACCAGAGTTTGAG
ATTGTTGGTTTTACAAACCACATCAGTGTGAATGTGAAATTTCAATTCGACAGTCCCGGG
ATACTAAGTGAAGAATTACAGTTTTACTTAGCATTTATTGAAGAGCATGCAGGGAACAGT
GTTAAGAGGCATCAACCCCAAATAACTGGAAACATCACCAAAAATTTCAATTATGTCATC
GACAAGTTAATTCCAAACACAAACTACTGTATATCCGTTTATTTTGAGCCTAAAGATCCA
AGAAAAATAAACAGATCTCCCTTAAAATGTACCCTCTTTCGACCCAGACGAGAATCAGAG
TCATCAGAATCTGCTACAATAGGAGGAATAATTACTCTGTTTTTAATAACTGCTGTCTTC
ATAAGCACTGTAATGATACTGAAACGGATTGGCTATATATGCTTAAGAAATGATTTCCCC
AAAGTTTTGAATTTTTATAAACTGTCAGTCTGGGTGTTTGCCGAGCTGCCCCCGTTGGAA
AAAGTGGCTACCGTGGAAGTCATTCACGTCAACAGGAAGAAGAAAGTGTGGAATTATAAT
TATGACGATGAAAATGACATCGAAAATGAGGCAGCTCCCCACTTAATTTCAGGTGGTTAC
ACCAAGCATGGACTAACGGGCAAGCTGTGTCCAACTTCCACCACTTCACCCAGCTTGGAG
GACTGCAGCTTGGAGGACTGCAGTGAGCCCAGTGCTGAGGAGCCGTATCTGCCTGAGCCC
AAGGGGGACGCCGAGACCCCCATGGCACCAGGGCCCGGCCTCTGGCAGTCGGAAGGCACA
AGTGGGGGCTACCAGACGAGAGGGACTCTGTGGCAGGACCCCACTTCCGAGGAGGACAGT
GACTCCACGGAGGGGTCTGAGGGCAGAATCGTCTTCAACGTGAATTTGAACTCTGTGTGT
GTGAGAGCCCTTGAGGATGACAAGGACTCAGAAGTCACTCTAATGTCCCCATCTTGTCCA
GAAGAGACAGTCGAGCTGGAGGACCTCAACGAGACAGAATCAAGCGTTTTGGTGGCCAGT
GAAGAAGGGACACAGCTGCCCTTCACCAACCCCTCTACGGAGTGCCCGAGGCCCCAAGAT
GCTCCTTCTGATAAAAGTGACACTTCCGATCCAGATGTTGACATGGGGGATGGGTATATA
GTAAGACAAGTGAATCTAAAAAAATTTAATTAA
Protein Properties
Number of Residues 530
Molecular Weight 59584.0
Theoretical pI 4.52
Pfam Domain Function Not Available
Signals
  • 1-26
Transmembrane Regions
  • 247-267
Protein Sequence
>Interferon-alpha/beta receptor beta chain
MLLSQNVSAIGPLNLYPMVHISLVFGISYVAPVLSDEHCTLKMRFRNFQSVLSWELKNHS
IVPTHYTLWYTIMSKREDMKVVKDCINVTRSFCDLTDVWVNTTDMYIPQVVGFRENAKLV
ICMGSFFLVPDKPLDPPEFEIVGFTNHISVNVKFQFDSPGILSEELQFYLAFIEEHAGNS
VKRHQPQITGNITKNFNYVIDKLIPNTNYCISVYFEPKDPRKINRSPLKCTLFRPRRESE
SSESATIGGIITLFLITAVFISTVMILKRIGYICLRNDFPKVLNFYKLSVWVFAELPPLE
KVATVEVIHVNRKKKVWNYNYDDENDIENEAAPHLISGGYTKHGLTGKLCPTSTTSPSLE
DCSLEDCSEPSAEEPYLPEPKGDAETPMAPGPGLWQSEGTSGGYQTRGTLWQDPTSEEDS
DSTEGSEGRIVFNVNLNSVCVRALEDDKDSEVTLMSPSCPEETVELEDLNETESSVLVAS
EEGTQLPFTNPSTECPRPQDAPSDKSDTSDPDVDMGDGYIVRQVNLKKFN
GenBank ID Protein AAB84233.1
UniProtKB/Swiss-Prot ID Q95141
UniProtKB/Swiss-Prot Entry Name INAR2_BOVIN
PDB IDs Not Available
GenBank Gene ID U75304
GeneCard ID IFNAR2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available