Showing Protein Interferon alpha/beta receptor 2 (BMDBP02592)
Identification | |
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BMDB Protein ID | BMDBP02592 |
Secondary Accession Numbers | None |
Name | Interferon alpha/beta receptor 2 |
Synonyms | Not Available |
Gene Name | IFNAR2 |
Protein Type | Enzyme |
Biological Properties | |
General Function | Not Available |
Specific Function | Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Mediates signal transduction via its association with the TYR kinase, JAK1. |
Pathways | Not Available |
Reactions | Not Available |
GO Classification | Not Available |
Cellular Location | Not Available |
Gene Properties | |
Chromosome Location | 1 |
Locus | Not Available |
SNPs | IFNAR2 |
Gene Sequence |
>1593 bp ATGCTTTTGAGCCAGAATGTGTCAGCGATTGGACCACTGAATTTGTATCCCATGGTGCAC ATCAGCCTCGTGTTTGGTATTTCGTATGTTGCGCCTGTTCTTTCAGATGAACATTGCACT TTAAAGATGAGATTCCGAAATTTCCAGTCAGTCTTATCATGGGAATTAAAAAACCATTCA ATTGTACCAACTCACTATACATTATGGTACACAATCATGAGTAAACGAGAAGATATGAAG GTCGTCAAGGACTGTATAAACGTCACAAGATCGTTTTGTGACCTCACAGACGTGTGGGTA AACACGACGGACATGTACATCCCCCAGGTGGTTGGATTCAGAGAGAATGCAAAGCTGGTC ATTTGTATGGGCTCTTTCTTCCTGGTGCCAGACAAGCCTTTGGACCCACCAGAGTTTGAG ATTGTTGGTTTTACAAACCACATCAGTGTGAATGTGAAATTTCAATTCGACAGTCCCGGG ATACTAAGTGAAGAATTACAGTTTTACTTAGCATTTATTGAAGAGCATGCAGGGAACAGT GTTAAGAGGCATCAACCCCAAATAACTGGAAACATCACCAAAAATTTCAATTATGTCATC GACAAGTTAATTCCAAACACAAACTACTGTATATCCGTTTATTTTGAGCCTAAAGATCCA AGAAAAATAAACAGATCTCCCTTAAAATGTACCCTCTTTCGACCCAGACGAGAATCAGAG TCATCAGAATCTGCTACAATAGGAGGAATAATTACTCTGTTTTTAATAACTGCTGTCTTC ATAAGCACTGTAATGATACTGAAACGGATTGGCTATATATGCTTAAGAAATGATTTCCCC AAAGTTTTGAATTTTTATAAACTGTCAGTCTGGGTGTTTGCCGAGCTGCCCCCGTTGGAA AAAGTGGCTACCGTGGAAGTCATTCACGTCAACAGGAAGAAGAAAGTGTGGAATTATAAT TATGACGATGAAAATGACATCGAAAATGAGGCAGCTCCCCACTTAATTTCAGGTGGTTAC ACCAAGCATGGACTAACGGGCAAGCTGTGTCCAACTTCCACCACTTCACCCAGCTTGGAG GACTGCAGCTTGGAGGACTGCAGTGAGCCCAGTGCTGAGGAGCCGTATCTGCCTGAGCCC AAGGGGGACGCCGAGACCCCCATGGCACCAGGGCCCGGCCTCTGGCAGTCGGAAGGCACA AGTGGGGGCTACCAGACGAGAGGGACTCTGTGGCAGGACCCCACTTCCGAGGAGGACAGT GACTCCACGGAGGGGTCTGAGGGCAGAATCGTCTTCAACGTGAATTTGAACTCTGTGTGT GTGAGAGCCCTTGAGGATGACAAGGACTCAGAAGTCACTCTAATGTCCCCATCTTGTCCA GAAGAGACAGTCGAGCTGGAGGACCTCAACGAGACAGAATCAAGCGTTTTGGTGGCCAGT GAAGAAGGGACACAGCTGCCCTTCACCAACCCCTCTACGGAGTGCCCGAGGCCCCAAGAT GCTCCTTCTGATAAAAGTGACACTTCCGATCCAGATGTTGACATGGGGGATGGGTATATA GTAAGACAAGTGAATCTAAAAAAATTTAATTAA |
Protein Properties | |
Number of Residues | 530 |
Molecular Weight | 59584.0 |
Theoretical pI | 4.52 |
Pfam Domain Function | Not Available |
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Interferon-alpha/beta receptor beta chain MLLSQNVSAIGPLNLYPMVHISLVFGISYVAPVLSDEHCTLKMRFRNFQSVLSWELKNHS IVPTHYTLWYTIMSKREDMKVVKDCINVTRSFCDLTDVWVNTTDMYIPQVVGFRENAKLV ICMGSFFLVPDKPLDPPEFEIVGFTNHISVNVKFQFDSPGILSEELQFYLAFIEEHAGNS VKRHQPQITGNITKNFNYVIDKLIPNTNYCISVYFEPKDPRKINRSPLKCTLFRPRRESE SSESATIGGIITLFLITAVFISTVMILKRIGYICLRNDFPKVLNFYKLSVWVFAELPPLE KVATVEVIHVNRKKKVWNYNYDDENDIENEAAPHLISGGYTKHGLTGKLCPTSTTSPSLE DCSLEDCSEPSAEEPYLPEPKGDAETPMAPGPGLWQSEGTSGGYQTRGTLWQDPTSEEDS DSTEGSEGRIVFNVNLNSVCVRALEDDKDSEVTLMSPSCPEETVELEDLNETESSVLVAS EEGTQLPFTNPSTECPRPQDAPSDKSDTSDPDVDMGDGYIVRQVNLKKFN |
External Links | |
GenBank ID Protein | AAB84233.1 |
UniProtKB/Swiss-Prot ID | Q95141 |
UniProtKB/Swiss-Prot Entry Name | INAR2_BOVIN |
PDB IDs | Not Available |
GenBank Gene ID | U75304 |
GeneCard ID | IFNAR2 |
GenAtlas ID | Not Available |
HGNC ID | Not Available |
References | |
General References | Not Available |