Showing Protein Angiopoietin-1 (BMDBP02593)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02593 |
| Secondary Accession Numbers | None |
| Name | Angiopoietin-1 |
| Synonyms | Not Available |
| Gene Name | ANGPT1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in receptor binding |
| Specific Function | Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 14 |
| Locus | Not Available |
| SNPs | ANGPT1 |
| Gene Sequence |
>1494 bp ATGACAGTTTTCCTTTCCTTTGCTTTCCTCGCTGCTATTCTGACTCACATAGGGTGCAGC AACCAGCGCCGAAGTCCAGAAAACGGTGGGAGAAGATATAACCGGATTCAACATGGGCAA TGTGCCTACACTTTCATTCTTCCAGAACACGACGGTAACTGTCGTGAGAGTACGACAGAC CAGTACAACACAAACGCTCTGCAGAGAGATGCTCCACACGTGGAACAGGATTTCTCTTCC CAGAAACTTCAACATCTGGAGCATGTGATGGAAAATTATACTCAGTGGCTGCAAAAAATT GAGAATTACATTGTGGAAAATATGAAGTCGGAGATGGCTCAGATACAGCAGAATGCAGTT CAGAACCACACGGCCACCATGCTCGAGATAGGGACCAGCCTCCTCTCTCAGACCGCAGAG CAGACCAGAAAGCTGACAGATGTAGAGACCCAGGTACTAAATCAAACATCTCGACTTGAA ATACAACTGCTGGAGAATTCATTATCAACCTACAAGCTAGAGAAACAACTTCTTCAACAG ACAAATGAAATCTTAAAGATTCATGAGAAAAACAGTTTATTAGAACACAAAATCTTTGAA ATGGAGGGAAAGCACAAGGAAGAATTGGACACCTTAAAGGAAGAGAAAGAGAATCTTCAA GGCTTGGTTACTCGTCAGACGTACATAATCCAGGAACTGGAGAAACAGTTGAACAGAGCC ACCACCAATAACAGTGTCCTTCAGAAGCAGCAGCTGGAGCTCATGGACACAGTGCACAAC CTCGTCAACCTCTGCACTAAAGAAGTTTTACTAAAGGGAGGAAAAAAAGAGGAAGAAAAG CCATTTAGAGACTGTGCAGATGTATATCAAGCTGGTTTTAATAAAAGTGGAATCTACACT ATTTATATTAATAATATGCCAGAACCCAAAAAGGTATTTTGCAATATGGATCTCAACGGG GGAGGTTGGACTGTAATACAGCATCGTGAAGACGGAAGTCTAGATTTCCAAAGAGGTTGG AAAGAATATAAAATGGGTTTTGGAAATCCCTCTGGTGAATATTGGTTGGGGAACGAGTTT ATTTTTGCCATAACCAGTCAGAGGCAGTACACTCTAAGAATTGAGTTATTGGACTGGGAA GGAAACCGAGCCTATTCACAGTATGACAGATTCCACATAGGAAATGAAAAGCAGAACTAC AGGTTGTATTTGAAGGGTCACACTGGGACAGCAGGAAAACAGAGCAGCCTGATCTTGCAT GGTGCTGATTTCAGCACTAAAGATGCTGATAACGACAACTGCATGTGCAAATGTGCCCTC ATGCTAACAGGAGGCTGGTGGTTTGATGCCTGTGGCCCATCCAATCTAAATGGAATGTTT TATACAGCGGGACAGAACCATGGAAAACTGAATGGAATAAAATGGCATTATTTCAAAGGG CCCAGTTACTCCTTACGTTCCACAACTATGATGATTCGACCTTTGGACTTTTGA |
| Protein Properties | |
| Number of Residues | 497 |
| Molecular Weight | 57429.0 |
| Theoretical pI | 6.75 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Angiopoietin-1 MTVFLSFAFLAAILTHIGCSNQRRSPENGGRRYNRIQHGQCAYTFILPEHDGNCRESTTD QYNTNALQRDAPHVEQDFSSQKLQHLEHVMENYTQWLQKIENYIVENMKSEMAQIQQNAV QNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQ TNEILKIHEKNSLLEHKIFEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRA TTNNSVLQKQQLELMDTVHNLVNLCTKEVLLKGGKKEEEKPFRDCADVYQAGFNKSGIYT IYINNMPEPKKVFCNMDLNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEF IFAITSQRQYTLRIELLDWEGNRAYSQYDRFHIGNEKQNYRLYLKGHTGTAGKQSSLILH GADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKG PSYSLRSTTMMIRPLDF |
| External Links | |
| GenBank ID Protein | AAI23629.1 |
| UniProtKB/Swiss-Prot ID | O18920 |
| UniProtKB/Swiss-Prot Entry Name | ANGP1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC123628 |
| GeneCard ID | ANGPT1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |