Showing Protein Proto-oncogene vav (BMDBP02600)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02600 |
| Secondary Accession Numbers | None |
| Name | Proto-oncogene vav |
| Synonyms | Not Available |
| Gene Name | VAV1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in diacylglycerol binding |
| Specific Function | Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 7 |
| Locus | Not Available |
| SNPs | VAV1 |
| Gene Sequence |
>2535 bp ATGGAGCTGTGGCGCCAGTGCACCCACTGGCTCATCCAGTGCCGGGTGCTACCGCCCAGC CACCGTGTGACCTGGGATGGAGCCCAAGTGTGCGAGCTGGCGCAGGCCCTCCGGGATGGC GTCCTTCTGTGCCAGCTGCTCAACAACCTGCTGCCCCATGCCATCAACCTGCGGGAAGTC AACCTGCGTCCCCAGATGTCCCAGTTCCTCTGCCTTAAGAATATCCGCACCTTTCTGTCT ACCTGCTACGAGAAGTTTGGCCTCAAGCGGAGTGAACTCTTTGAGGCCTTCGACCTCTTC GATGTGCAGGATTTTGGCAAGGTCATCTACACCCTGTCCGCTCTGTCCTGGACCCCGATT GCCCAGAACAAGGGGATCATGCCCTTCCCCACTGAGGAGAGTGTGGGTGATGAAGACATC TACAGTGGCCTGTCCGACCAGATCGACGACACGGTGGAGGAGGATGAGGACCTGTACGAC TGCGTGGAGAACGAGGAGGCAGAGGGCGACGAGGTCTACGAGGACCTCATGCGCTCGGAG CCGGTGCCCATGCCGCCCAAGATGACAGAGTATGACAAGCGGTGCTGCTGTCTGCGGGAG ATCCAGCAGACGGAGGAGAAGTATACGGACACGCTGGGCTCCATCCAACAGCATTTTATG AAGCCCTTGCAGCGGTTCCTTAAACCCCAAGACGTCGAGATTATCTTCATCAACATTGAG GACCTGCTTCGTGTACACACCCATTTCCTAAAGGAGATGAAGGAAGCCCTGGCCAACCCT GGTGCATCCACCCTCTACCAGGTCTTCATCAAATACAAGGAGAGGTTCCTCATCTATGGC CGCTACTGTAGCCAGGTGGAGTCTGCCAGCAAGCACCTGGACCGTGTGGCCACAGCCCGG GAGGATGTACAAATGAAGCTGGAAGAATGTAGTCAGCGCGCCAACAACGGGAGGTTCACC TTAAGGGACCTGTTGATGGTGCCCATGCAGCGAGTGCTCAAATATCACCTCCTGCTCCAG GAGCTGGTGAAACACACACAGGATGCAATGGAGAAGGACAACTTGCGGCTGGCCCTAGAT GCCATGAGGGACCTGGCACAGTGCGTAAACGAGGTCAAGCGGGACAATGAGACGCTGCGG CAGATTACCAACTTCCAGCTGTCCATCGAGAACCTGGACCAGTCTCTAGCCCACTACGGC CGACCCAAGATCGATGGTGAGCTGAAGATAACTTCGGTGGAGAGGCGCTCCAAGATGGAC AGGTATGCCTTCCTGCTTGACAAAGCTCTGCTCATCTGTAAGCGCCGAGGGGACACCTAC GACCTCAAGGACTTTGTGAACCTGCACAGCTTCCAGGTTCGAGATGACTCCTCCGGAGAG AGGGACAACAAGAAGTGGACTCACATGTTCCTCCTGATTGAGGACCAAGGTGCCCAGGGC TATGAGCTGTTCTTCAAGACACGAGAACTAAAGAAGAAGTGGATGGAGCAGTTCGAGATG GCCATCTCCAACATCTACCCCGAGAACGCCACTGCCAATGGTCATGACTTTCAGATGTTT TCCTTTGAGGAGACCACATCCTGCAAGGCTTGCCAGATGCTGCTGAGAGGCACTTTCTAT CAGGGGTACCGCTGTCAACGGTGCCGAGCACCTGCACACAAGGAGTGTCTTGGGAGGGTC CCTCCGTGTGGTCGACATGGACAAGATTATTCAGGAACTATGAAGAAGGATAAGCCACAT CGGCGGGCTCAAGACAAAAAGAGGAATGAGCTAGGCCTGCCCAAGATGGAGGTGTGCCAG GAATACTACGGGCTGCCCCCACCCCCTGGAGCCATTGGACCTTTTTTGCGCCTCAACCCG GGAGACATTGTGGAGCTCACTAAGGCTGAAGCCGAACAGAACTGGTGGGAGGGAAGGAAT ATATCTACCAATGAAGTCGGCTGGTTTCCCTGCAATAGGGTCAAGCCCTACGTGCATGGT CCCCCTCAGGACCTGTCCGTTCATCTCTGGTACGCTGGCCCCATGGAGCGAGCCGGGGCG GAAAGCATTCTTACCAACCGCTCGGATGGGACGTTCTTGGTGCGGCAGAGGGTGAAGGAT GCCGCGGAATTTGCCATCAGTATTAAGTATAATGTTGAAGTCAAGCATATTAAAATCATG ACAGCAGAAGGACTGTACCGGATTACAGAAAAGAAAGCTTTCAGGGGACTTACGGAGCTG GTGGAATTCTACCAACAGAACTCTCTGAAGGATTGCTTCAAGTCGCTGGACACCACCCTG CAGTTCCCCTTCAAGGAGCCTGAGAGGAGAGCCATCAACAAACCATCAGCCGGGAGCATC AAGATCTTTGGCACTGCTAAAGCCCGCTATGACTTCTGCGCCCGGGACCGGTCAGAGCTG TCCCTCAAAGAGGGCGACATCGTCAAGATCCTTAACAAGAAGGGGCAGCAGGGCTGGTGG CGAGGGGAGATCTATGGCCGGATTGGCTGGTTCCCCTCCAACTATGTGGAAGAGGACTAT TCTGAGTACTGCTGA |
| Protein Properties | |
| Number of Residues | 844 |
| Molecular Weight | 98243.0 |
| Theoretical pI | 6.63 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Proto-oncogene vav MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREV NLRPQMSQFLCLKNIRTFLSTCYEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPI AQNKGIMPFPTEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEVYEDLMRSE PVPMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDVEIIFINIE DLLRVHTHFLKEMKEALANPGASTLYQVFIKYKERFLIYGRYCSQVESASKHLDRVATAR EDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDAMEKDNLRLALD AMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMD RYAFLLDKALLICKRRGDTYDLKDFVNLHSFQVRDDSSGERDNKKWTHMFLLIEDQGAQG YELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFY QGYRCQRCRAPAHKECLGRVPPCGRHGQDYSGTMKKDKPHRRAQDKKRNELGLPKMEVCQ EYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNISTNEVGWFPCNRVKPYVHG PPQDLSVHLWYAGPMERAGAESILTNRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIM TAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPERRAINKPSAGSI KIFGTAKARYDFCARDRSELSLKEGDIVKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDY SEYC |
| External Links | |
| GenBank ID Protein | AAI23647.1 |
| UniProtKB/Swiss-Prot ID | Q08DN7 |
| UniProtKB/Swiss-Prot Entry Name | VAV_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC123646 |
| GeneCard ID | VAV1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |