Identification
BMDB Protein ID BMDBP02688
Secondary Accession Numbers None
Name Sodium-dependent dopamine transporter
Synonyms Not Available
Gene Name SLC6A3
Protein Type Enzyme
Biological Properties
General Function Involved in dopamine:sodium symporter activity
Specific Function Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs SLC6A3
Gene Sequence Not Available
Protein Properties
Number of Residues 693
Molecular Weight 75691.0
Theoretical pI 8.42
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 69-89
  • 97-116
  • 140-160
  • 235-253
  • 262-279
  • 315-332
  • 344-365
  • 398-417
  • 444-462
  • 478-498
  • 519-538
  • 557-575
Protein Sequence
>Sodium-dependent dopamine transporter
MSEGRCSVAHMSSVVAPAKEANAMGPKAVELVLVKEQNGVQLTNSTLLNPPQSPTEAQDR
ETWSKKADFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLFFMVVAGVPLFYMELAL
GQFNREGAAGVWKICPILRGVGYTAILISLYIGFFYNVIIAWALHYLLSSFTTELPWTHC
NHSWNSPRCSDARAPNASSGPNGTSRTTPAAEYFERGVLHLHESQGIDDLGPPRWQLTSC
LVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLFALLLRGITLPGAVDAIRAYLSVDFH
RLCEASVWIDAAIQICFSLGVGLGVLIAFSSYNKFTNNCYRDAIITTSVNSLTSFSSGFV
VFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEALATLPLSSVWAVVFFVMLLTLGIDSA
MGGMESVITGLADEFQLLHRHRELFTLLVVLATFLLSLFCVTNGGIYVFTLLDHFAAGTS
ILFGVLMEVIGVAWFYGVWQFSDDIKQMTGRRPSLYWRLCWKFVSPCFLLFVVVVSIATF
RPPHYGAYVFPEWATALGWAIAASSMSVVPIYAAYKLCSLPGSSREKLAYAITPETEHGR
VDSGGGAPVHAPPLARGVGRWRKRKSCWVPSRGPGRGGPPTPSPRLAGHTRAFPWTGAPP
VPRELTPPSTCRCVPPLVCAHPAVESTGLCSVY
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P27922
UniProtKB/Swiss-Prot Entry Name SC6A3_BOVIN
PDB IDs Not Available
GenBank Gene ID M80234
GeneCard ID SLC6A3
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available