Identification
BMDB Protein ID BMDBP02700
Secondary Accession Numbers None
Name EF-hand domain-containing protein D2
Synonyms Not Available
Gene Name EFHD2
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 16
Locus Not Available
SNPs EFHD2
Gene Sequence
>729 bp
ATGGCCACGGACGAGCTGGCCAGCAAGCTAAGCCGGCGGCTGCAGATGGAGGGCGAGGGC
GGCGGCGAGGCCCCGGAGCAGCCCGGGCTGAACGGGGCGGCGGCGGCGGCGGCGGCGGCG
GGAGCGCCCGACGAGACGGCCGAGGCGCTGGGCAGCGCGGACGAAGAGCTGAGCGCCAAG
CTGCTGCGGCGCGCCGACCTCAACCAGGGTATCGGCGAGCCCCAGTCACCCAGCCGCCGC
GTCTTCAACCCTTACACTGAGTTCAAGGAGTTCTCCAGGAAGCAGATCAAGGACATGGAG
AAGATGTTCAAGGAGTACGATGCCGGCCGGGATGGATTCATTGACCTGATGGAGCTAAAG
CTCATGATGGAGAAACTTGGAGCCCCCCAGACCCACCTGGGCCTGAAAAATATGATCAAG
GAGGTGGATGAGGATTTTGACAGCAAGCTCAGCTTCCGGGAGTTCCTCCTGATTTTCCGC
AAGGCAGCAGCCGGGGAGCTGCAGGAGGACAGCGGGCTGCACGTGCTGGCCCGCCTCTCT
GAGATCGACGTGTCCACCGAGGGTGTCAAGGGGGCCAAGAGCTTCTTTGAGGCCAAGGTC
CAGGCCATGAACGTGTCCAGCCGCTTCGAGGAGGAGATCAAGGCAGAGCAGGAGGAGAGG
AAGAAGCAGGCGGAGGAGATGAAGCAGCGGAAAGCGGCCTTCAAGGAGCTGCAGTCCACC
TTCAAGTAG
Protein Properties
Number of Residues 242
Molecular Weight 26918.0
Theoretical pI 4.8
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 165-188
  • 222-243
  • 328-349
  • 389-410
Protein Sequence
>EF-hand domain-containing protein D2
MATDELASKLSRRLQMEGEGGGEAPEQPGLNGAAAAAAAAGAPDETAEALGSADEELSAK
LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKEYDAGRDGFIDLMELK
LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLS
EIDVSTEGVKGAKSFFEAKVQAMNVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
FK
GenBank ID Protein AAI40481.1
UniProtKB/Swiss-Prot ID A5D7A0
UniProtKB/Swiss-Prot Entry Name EFHD2_BOVIN
PDB IDs Not Available
GenBank Gene ID BC140480
GeneCard ID EFHD2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available