| Identification |
|---|
| BMDB Protein ID
| BMDBP02700 |
| Secondary Accession Numbers
| None |
| Name
| EF-hand domain-containing protein D2 |
| Synonyms
|
Not Available
|
| Gene Name
| EFHD2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 16 |
| Locus
| Not Available |
| SNPs
| EFHD2 |
| Gene Sequence
|
>729 bp
ATGGCCACGGACGAGCTGGCCAGCAAGCTAAGCCGGCGGCTGCAGATGGAGGGCGAGGGC
GGCGGCGAGGCCCCGGAGCAGCCCGGGCTGAACGGGGCGGCGGCGGCGGCGGCGGCGGCG
GGAGCGCCCGACGAGACGGCCGAGGCGCTGGGCAGCGCGGACGAAGAGCTGAGCGCCAAG
CTGCTGCGGCGCGCCGACCTCAACCAGGGTATCGGCGAGCCCCAGTCACCCAGCCGCCGC
GTCTTCAACCCTTACACTGAGTTCAAGGAGTTCTCCAGGAAGCAGATCAAGGACATGGAG
AAGATGTTCAAGGAGTACGATGCCGGCCGGGATGGATTCATTGACCTGATGGAGCTAAAG
CTCATGATGGAGAAACTTGGAGCCCCCCAGACCCACCTGGGCCTGAAAAATATGATCAAG
GAGGTGGATGAGGATTTTGACAGCAAGCTCAGCTTCCGGGAGTTCCTCCTGATTTTCCGC
AAGGCAGCAGCCGGGGAGCTGCAGGAGGACAGCGGGCTGCACGTGCTGGCCCGCCTCTCT
GAGATCGACGTGTCCACCGAGGGTGTCAAGGGGGCCAAGAGCTTCTTTGAGGCCAAGGTC
CAGGCCATGAACGTGTCCAGCCGCTTCGAGGAGGAGATCAAGGCAGAGCAGGAGGAGAGG
AAGAAGCAGGCGGAGGAGATGAAGCAGCGGAAAGCGGCCTTCAAGGAGCTGCAGTCCACC
TTCAAGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 242 |
| Molecular Weight
| 26918.0 |
| Theoretical pI
| 4.8 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 165-188
- 222-243
- 328-349
- 389-410
|
| Protein Sequence
|
>EF-hand domain-containing protein D2
MATDELASKLSRRLQMEGEGGGEAPEQPGLNGAAAAAAAAGAPDETAEALGSADEELSAK
LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKEYDAGRDGFIDLMELK
LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLS
EIDVSTEGVKGAKSFFEAKVQAMNVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
FK
|
| External Links |
|---|
| GenBank ID Protein
| AAI40481.1 |
| UniProtKB/Swiss-Prot ID
| A5D7A0 |
| UniProtKB/Swiss-Prot Entry Name
| EFHD2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC140480 |
| GeneCard ID
| EFHD2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
