Identification |
BMDB Protein ID
| BMDBP02700 |
Secondary Accession Numbers
| None |
Name
| EF-hand domain-containing protein D2 |
Synonyms
|
Not Available
|
Gene Name
| EFHD2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in calcium ion binding |
Specific Function
| May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 16 |
Locus
| Not Available |
SNPs
| EFHD2 |
Gene Sequence
|
>729 bp
ATGGCCACGGACGAGCTGGCCAGCAAGCTAAGCCGGCGGCTGCAGATGGAGGGCGAGGGC
GGCGGCGAGGCCCCGGAGCAGCCCGGGCTGAACGGGGCGGCGGCGGCGGCGGCGGCGGCG
GGAGCGCCCGACGAGACGGCCGAGGCGCTGGGCAGCGCGGACGAAGAGCTGAGCGCCAAG
CTGCTGCGGCGCGCCGACCTCAACCAGGGTATCGGCGAGCCCCAGTCACCCAGCCGCCGC
GTCTTCAACCCTTACACTGAGTTCAAGGAGTTCTCCAGGAAGCAGATCAAGGACATGGAG
AAGATGTTCAAGGAGTACGATGCCGGCCGGGATGGATTCATTGACCTGATGGAGCTAAAG
CTCATGATGGAGAAACTTGGAGCCCCCCAGACCCACCTGGGCCTGAAAAATATGATCAAG
GAGGTGGATGAGGATTTTGACAGCAAGCTCAGCTTCCGGGAGTTCCTCCTGATTTTCCGC
AAGGCAGCAGCCGGGGAGCTGCAGGAGGACAGCGGGCTGCACGTGCTGGCCCGCCTCTCT
GAGATCGACGTGTCCACCGAGGGTGTCAAGGGGGCCAAGAGCTTCTTTGAGGCCAAGGTC
CAGGCCATGAACGTGTCCAGCCGCTTCGAGGAGGAGATCAAGGCAGAGCAGGAGGAGAGG
AAGAAGCAGGCGGAGGAGATGAAGCAGCGGAAAGCGGCCTTCAAGGAGCTGCAGTCCACC
TTCAAGTAG
|
Protein Properties |
Number of Residues
| 242 |
Molecular Weight
| 26918.0 |
Theoretical pI
| 4.8 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
- 165-188
- 222-243
- 328-349
- 389-410
|
Protein Sequence
|
>EF-hand domain-containing protein D2
MATDELASKLSRRLQMEGEGGGEAPEQPGLNGAAAAAAAAGAPDETAEALGSADEELSAK
LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKEYDAGRDGFIDLMELK
LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLS
EIDVSTEGVKGAKSFFEAKVQAMNVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
FK
|
External Links |
GenBank ID Protein
| AAI40481.1 |
UniProtKB/Swiss-Prot ID
| A5D7A0 |
UniProtKB/Swiss-Prot Entry Name
| EFHD2_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC140480 |
GeneCard ID
| EFHD2 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |