Showing Protein Desmocollin-3 (BMDBP02713)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02713 |
| Secondary Accession Numbers | None |
| Name | Desmocollin-3 |
| Synonyms | Not Available |
| Gene Name | DSC3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 24 |
| Locus | 24q21-q22 |
| SNPs | DSC3 |
| Gene Sequence |
>2209 bp ACAGAAAGAGATTCTTGTGCTCCTGGAATATCAGAAGAAGGTATTGAAGAAAAGACACAC TAAAGAAACTGTTCTCAGGCGTTCCAAAAGGAGATGGGCGCCGATACCCTGCTCGATGCA GGAGAATTCCCTGGGACCTTTCCCCTTGTTCCTTCAACAGGTTCAATCTGATGCTGCACA GAACTATACCATCTTCTATTCAATAAGTGGGCGTGGAGTTGACAAGGAACCTTTAAATTT GTTTTTCATAGAAAGAGACACTGGAAATCTGTATTGTACCCAGCCTGTGGATCGTGAAGA ATATGACGTTTTTGATCTGATTGCCTACGCGTCAACTGCAGACGGATATTCAGCAGACTT CCCTCTCCCACTGCCCATCAGAGTGGAGGACGAAAATGACAACCATCCTATTTTCACAGA AGCAGTTTATAATTTTGAAGTTCCGGAAAGCAGTAGAGTTGGTACTACAGTGGGAGTGGT TTGTGCCACGGACAGAGATGAACCAGACACGATGCACACACGCCTGAAGTACAGCATTTT GGAGCAGACACCACGATCACCTGGGCTGTTTTCTGTGCATCCCAGCACGGGTGTGATCAC CACCGTCTCTCATTATTTGGACAGAGAGGTTGCAGACAAATACTCATTGATAATGAAAGT ACAAGATATGGATGGCCAGTTTTTTGGATTGATGAGTACAGCGACTTGCATCATAACAGT AAAAGATTCAAATGACAATTTGCCCACTTTCAGACAGAATGCCTATGAAGCATCAGTCGA GGAAAACACGGTCAATGTGGAAATTCTAAGAATACCCGTAGAAGATAAGGATTTGATTAA CACTGCCAATTGGAGAGCCAATTTTACTATTTTAAAGGGCAATGAAAATGGACATTTCAA AATCACTACAGACAAAGCAACTAATGAAGGTGTTTTGTCTGTTGTAAAGCCACTGGATTA TGAAGAAAGCCATCAAGTGGTCCTGGAAATTGGAGTGGCCAATGAAGCTCCATTTACTAG AGATGTTGCACTCAGGATGACAACCATGAACAGAGCTGTGGTCACAGTTCATGTGAAGGA TCAGGATGAAGGGCCTGAATGCAGCCCTGAAGTCCAGTATATACGGATTAAAGAAAACTC CGCAGTGGGTTCAAAGATCAGTGGCTATAAGGCATATGACCCTGAAACTAAAAGTTCCAG TGGTTTAAGGTACAAAATATTGCATGATCCTAAAGAGTGGATCACCGTTAATGAAGGTTC GGGCTCATTAGAGACTTACAAAACTTTGGACAGGGAGGTTATAACTCCCAAAAATGATTT GTATAATATTACAGTCCTGGCAATAGATCAAGATGGTAGATCATGTACTGGAACCCTCGC AGTTAGCATTGAAGATGTGAATGATAACCCACCAGAAATACTTCAAGATTATCTAGTTAT TTGCAAAGGAAACATGGACTATGTTGACATTTCGGCTATTGATCATGACAGTTCCATCAA CGGTGCTCCATTTTACTTCAGCTTGGCAAACACTTCTCCAGAAATCAACAGACTATGGAC GATCACCAGAGTTAATGATACAGCTGCCCGTCTTGCATATCAGAAAAATGCCCAATTTCA AGAATATTTCATTCCTGTTGCTGTAAAAGACAGAGCAGGGCTATCTGCAACAAAAACCTT GAGAGTGAACCTCTGTGATTGTACTAACCCCGTTCAATGCCGGGCTGCTCGACGGAGTGC GGACGTGATACTTGGCAAATGGGCGATCCTTGCCATACTTCTGGGCATAGCACTACTTTT CTCTATATTGCTAACTTTAGTATGTGGAATTGTTAGTGCCAGAAATAAAAAAGCTTTTCC AGATGATTTGGCCCAGCAAAATCTAATTATATCAAACACAGAAGCACCTGGAGATGATAA GGTGTGTTCTGCCAATGGGTTTATGACCCAGACAGTCAACAACGCTAACCAGGGCTTTTG TGGCACTATGGGATCTGGAGTCAAAAACGGAGGGCAGGAAAGCATTGAAATGGTGAAAGG AGGACAGCAGACGCTGGAGTCGTGCCGCGGGGCTGGGCATCATCACACCCTGGACTCCTG CAGAGGAGGCACTATTGAGGTGGAGAATTCCAGATACACTTACTCCGAGTGGCAAAATTT CACTCAACCCCGTCTTGGTGAAGAATCCATTAGAGGACACACTGGTTAA |
| Protein Properties | |
| Number of Residues | 896 |
| Molecular Weight | 99687.0 |
| Theoretical pI | 4.92 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Desmocollin-3 MAAPGSGAPCAELCRQLLLTLVVFSFACEACKKEIFNIPSKLEADKMIGRVNLKECLGSV DRIQSSDPDFRVLEDGSVYTAHAVVLSDEKRSFTIWLSDTEKRTQKEILVLLEYQKKVLK KRHTKETVLRRSKRRWAPIPCSMQENSLGPFPLFLQQVQSDAAQNYTIFYSISGRGVDKE PLNLFFIERDTGNLYCTQPVDREEYDVFDLIAYASTADGYSADFPLPLPIRVEDENDNHP IFTEAVYNFEVPESSRVGTTVGVVCATDRDEPDTMHTRLKYSILEQTPRSPGLFSVHPST GVITTVSHYLDREVADKYSLIMKVQDMDGQFFGLMSTATCIITVKDSNDNLPTFRQNAYE ASVEENTVNVEILRIPVEDKDLINTANWRANFTILKGNENGHFKITTDKATNEGVLSVVK PLDYEESHQVVLEIGVANEAPFTRDVALRMTTMNRAVVTVHVKDQDEGPECSPEVQYIRI KENSAVGSKISGYKAYDPETKSSSGLRYKILHDPKEWITVNEGSGSLETYKTLDREVITP KNDLYNITVLAIDQDGRSCTGTLAVSIEDVNDNPPEILQDYLVICKGNMDYVDISAIDHD SSINGAPFYFSLANTSPEINRLWTITRVNDTAARLAYQKNAQFQEYFIPVAVKDRAGLSA TKTLRVNLCDCTNPVQCRAARRSADVILGKWAILAILLGIALLFSILLTLVCGIVSARNK KAFPDDLAQQNLIISNTEAPGDDKVCSANGFMTQTVNNANQGFCGTMGSGVKNGGQESIE MVKGGQQTLESCRGAGHHHTLDSCRGGTIEVENSRYTYSEWQNFTQPRLGEKLHLCNQDE EHMPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEAKFAALAKTCTKR |
| External Links | |
| GenBank ID Protein | AAC41625.1 |
| UniProtKB/Swiss-Prot ID | Q28060 |
| UniProtKB/Swiss-Prot Entry Name | DSC3_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | L33774 |
| GeneCard ID | DSC3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |