Showing Protein Cadherin-1 (BMDBP02736)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP02736 |
| Secondary Accession Numbers | None |
| Name | Cadherin-1 |
| Synonyms | Not Available |
| Gene Name | CDH1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 18 |
| Locus | Not Available |
| SNPs | CDH1 |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 882 |
| Molecular Weight | 97938.0 |
| Theoretical pI | 4.51 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
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| Protein Sequence |
>Cadherin-1 MGPWSRSLSALCCCCRCNPWLCREPEPCIPGFGAESYTFTVPRRNLERGRVLGRVSFEGC AGLPRTVYVSDDTRFKVHTDGVLTVRRPVHLHRPELSFLVHAWDSTHRKLSTKVTLEVSA HHHHHHSHHDSPSGTQTEVLTFPGPHHGLRRQKRDWVIPPISCPENEKGPFPKSLVQIKS NKEKETQVFYSITGQRADTPPVGVFIIERETGWLKVTQPLDREQIAKYILFSHAVSSNGQ AIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAI GYTIPAQDPMLPHNKMFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNGEGLSTTAT AVITVLDTNDNAPRFNPTTYVGSVPENEANVAITTLTVTDADDPNTPAWEAVYTVLNDNE KQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILYVAVTNVAPFEVTLPTSTATVTVDVIDV NEAPIFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRIWRDTANWLEINPETG AISTRAELDREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPVPEPRTM DFCQRNPEPHIININDPDLPPNTSPFTAELTHGASVNWTIEYNDQERESLILKPKKTLEL GDHKINLKLIDNQNKDQVTTLDVHVCDCDGIVSNCRKARPAEAGLQVPAILGILGGILAF LILILLLLLLVRRRRVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARP EVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGS EAATLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD |
| External Links | |
| GenBank ID Protein | AAR91598.1 |
| UniProtKB/Swiss-Prot ID | Q6R8F2 |
| UniProtKB/Swiss-Prot Entry Name | CADH1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AY508164 |
| GeneCard ID | CDH1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |