Identification
BMDB Protein ID BMDBP02739
Secondary Accession Numbers None
Name Alpha-actinin-3
Synonyms Not Available
Gene Name ACTN3
Protein Type Enzyme
Biological Properties
General Function Involved in actin binding
Specific Function F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 29
Locus Not Available
SNPs ACTN3
Gene Sequence
>2706 bp
ATGATGATGGTTCTGCAGCCCGAGGGTCTGGGGACCGGGGAGGGGCCCTTCGCGGGCGGC
CGTGGGGGCGGCGAATACATGGAACAGGAGGAGGACTGGGACCGCGACCTGCTGTTGGAC
CCGGCCTGGGAGAAGCAGCAGCGGAAAACCTTCACTGCCTGGTGCAACTCACACCTGCGC
AAGGCTGGCACCCAGATCGAGAACATCGAGGAGGATTTCCGCAATGGCCTCAAACTCATG
TTGCTCCTGGAGGTTATTTCAGGAGAGAGGCTGCCCAGACCAGACAAAGGCAAGATGCGC
TTCCACAAGATTGCCAATGTCAACAAGGCCCTGGATTTCATTGCCAGCAAGGGGGTGAAG
CTGGTGTCCATCGGTGCTGAAGAGATTGTTGACGGGAACCTGAAGATGACCCTGGGCATG
ATCTGGACCATCATCCTTCGCTTTGCCATCCAGGACATCTCCGTGGAAGAAACCTCGGCC
AAGGAAGGCTTGCTCCTGTGGTGTCAGCGGAAGACGGCGCCGTACCGCAACGTCAACGTG
CAGAACTTCCACACCAGCTGGAAGGATGGGCTGGCCCTCTGTGCTCTCATCCACCGACAC
CGCCCCGACCTCATTGACTATGCCAAACTGCGCAAGGACGACCCCATCGGCAACTTGAAC
ACCGCCTTTGAGGTGGCCGAGAAGTACCTGGACATCCCTAAGATGCTGGATGCAGAAGAC
ATTGTGAACACCCCAAAGCCTGATGAGAAGGCCATCATGACCTATGTCTCCTGCTTCTAC
CACGCCTTTGCCGGGGCGGAGCAGGCAGAGACAGCTGCCAACAGGATCTGCAAAGTGCTG
GCCGTGAACCAGGAGAACGAGAAGCTGATGGAGGAATATGAAAAGCTGGCCAGTGAGCTA
CTGGAATGGATCCGCCGGACCGTGCCGTGGCTGGAGAACCGCGTGGGCGAGCCCAGCATG
AGCGCCATGCAACGCAAGCTGGAAGACTTCCGGGACTACCGGCGCCTGCACAAGCCGCCC
CGCGTGCAGGAGAAGTGCCAGCTGGAGATTAACTTCAACACACTGCAGACCAAGCTGCGG
CTGAGCCACCGGCCGGCCTTCATGCCATCTGAGGGCAAGCTGGTCTCGGACATCGCCAAC
GCATGGCGGGGCCTGGAGCAGGCAGAGAAGGGCTATGAGGATTGGCTGCTCTCCGAGATC
CGGCGCCTACAGCGGCTGCAGCACCTGGCGGAGAAGTTCCAGCAGAAGGCCTCCCTGCAT
GAAGCCTGGACCCGGGGAAAGGAGGACATGCTGAGCCAGAGGGACTACGAGACGGCTTCG
CTGCAGGAGGTGCGGGCCTTGCTGCGGCGCCACGAGGCCTTCGAGAGCGACCTGGCGGCG
CACCAGGACCGCGTGGAGCACATCGCTGCGCTGGCCCAGGAGCTCAATGAGCTGGACTAC
CACGAGGCAGCCTCGGTGAACAGCCGCTGCCAGGCCATCTGTGACCAGTGGGACAACCTG
GGCACGCTGACCCAGAAGAGGCGGGATGCACTGGAGCGGATGGAGAAGCTCCTAGAGACC
ATCGATCAGCTACAGCTGGAGTTTGCCCGGCGGGCAGCGCCCTTCAACAACTGGCTGGAC
GGCGCCGTGGAGGACCTGCAGGACGTGTGGCTGGTGCACTCGGTGGAGGAGACCCAGAGC
TTGGTGACAGCACACGACCAGTTCAAGGCAACACTGCCCGAGGCCGACCGAGAGAGGGGT
GCCATCCTGGGCATCCAGGGTGAGATCCAGAAGATCTGCCAAACGTACGGACTGCGGCCC
AGCTCCACCAACCCCTACATCACCCTCACCCCGCAGGACATCAACACCAAGTGGGACACG
GTCCGAAAGCTGGTACCCAGCCGTGACCAGATGCTGCAGGAGGAGCTGACGCGGCAGCAG
GTGAACGAGAGGCTCCGGCGGCAGTTTGCAGCCCAGGCCAACGCCATCGGGCCCTGGATC
CAGGGGAAGGTGGAGGAAGTGGGGCGCCTAGCCGCGGGGATGGCCGGCTCTCTGGAGGAG
CAGATGGCGGGCCTGCGGCAGCAGGAGCAGAATATCATCAACTACAAGAGCAACATCGAC
CGGCTGGAGGGAGACCACCAGCTGCTGCAGGAGAGTCTGGTGTTTGACAACAAGCACACG
GTCTACAGCATGGAGCACATCCGCGTGGGCTGGGAGCAGCTGCTCACCTCCATCGCACGC
ACCATCAACGAGGTGGAGAACCAGGTACTGACCCGAGACGCCAAGGGCCTGAGTCAGGAG
CAGCTCAACGAGTTCCGGGCATCTTTCAACCACTTTGACCGGAAGCGGAATGGCATGATG
GAGCCTGATGACTTCCGGGCCTGCCTCATCTCCATGGGCTATGACCTGGGGGAGGTGGAG
TTCGCTCGCATCATGACCATGGTGGACCCCAACGCAGCTGGGGTTGTGACCTTCCAAGCC
TTCATCGACTTTATGACCCGAGAGACAGCCGAGACAGACACGGCTGAGCAGGTTGTGGCC
TCGTTCAAGATCCTGGCGGGAGACAAGAACTACATCACCGCCGAGGAGCTGCGGCGGGAA
CTCCCGGCGGAGCAGGCCGAGTACTGCATCCGCCGCATGGCGCCCTACAAGGGGGCTGGG
GCTCCAGCTGGAGCCCTGGACTACGTGGCCTTCTCCAGTGCCCTCTACGGGGAGAGTGAC
CTCTGA
Protein Properties
Number of Residues 901
Molecular Weight 103151.0
Theoretical pI 5.12
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Alpha-actinin-3
MMMVLQPEGLGTGEGPFAGGRGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLR
KAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVK
LVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNV
QNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAED
IVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASEL
LEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLR
LSHRPAFMPSEGKLVSDIANAWRGLEQAEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLH
EAWTRGKEDMLSQRDYETASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDY
HEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLD
GAVEDLQDVWLVHSVEETQSLVTAHDQFKATLPEADRERGAILGIQGEIQKICQTYGLRP
SSTNPYITLTPQDINTKWDTVRKLVPSRDQMLQEELTRQQVNERLRRQFAAQANAIGPWI
QGKVEEVGRLAAGMAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQESLVFDNKHT
VYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMM
EPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVA
SFKILAGDKNYITAEELRRELPAEQAEYCIRRMAPYKGAGAPAGALDYVAFSSALYGESD
L
GenBank ID Protein AAI22619.1
UniProtKB/Swiss-Prot ID Q0III9
UniProtKB/Swiss-Prot Entry Name ACTN3_BOVIN
PDB IDs Not Available
GenBank Gene ID BC122618
GeneCard ID ACTN3
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available