Identification
BMDB Protein ID BMDBP02765
Secondary Accession Numbers None
Name Fibrillin-1
Synonyms Not Available
Gene Name FBN1
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus where they provide tensile strength and have anchoring roles. Fibrillin-1 also plays a key role in tissue homeostasis through specific interactions with growth factors, such as the bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs) and latent transforming growth factor-beta-binding proteins (LTBPs), cell-surface integrins and other extracellular matrix protein and proteoglycan components. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Negatively regulates osteoclastogenesis by binding and sequestering an osteoclast differentiation and activation factor TNFSF11. This leads to disruption of TNFSF11-induced Ca(2+) signaling and impairment of TNFSF11-mediated nuclear translocation and activation of transcription factor NFATC1 which regulates genes important for osteoclast differentiation and function. Mediates cell adhesion via its binding to cell surface receptors integrins ITGAV:ITGB3 and ITGA5:ITGB1. Binds heparin and this interaction plays an important role in the assembly of microfibrils.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 10
Locus Not Available
SNPs FBN1
Gene Sequence
>8616 bp
ATGCGGCGAGGGGGGCTGCTGGAGGTCGCCTTGGGATTTACCGTGCTCTTAGCGTCCTAC
ACGAGCCATGGGGCGGATACCAATTTGGAGGCTGGGAACGTGAAGGAAACCAGAGCCAAC
CGGGCCAAGAGAAGAGGTGGCGGAGGACACAACGCGCTTAAAGGACCCAATGTCTGTGGA
TCACGTTATAATGCTTACTGTTGCCCTGGATGGAAGACTTTACCTGGTGGAAATCAGTGT
ATTGTCCCCATTTGCCGGCATTCCTGTGGGGATGGATTTTGTTCGAGGCCAAATATGTGC
ACTTGCCCATCTGGTCAGATAGCTCCTTCCTGTGGCTCCAGATCCATCCAACATTGTAAC
ATTCGCTGCATGAATGGAGGTAGCTGCAGTGATGATCATTGTCTGTGCCAGAAAGGATAC
ATAGGGACTCACTGTGGACAACCCGTCTGTGAAAGTGGCTGTCTTAACGGAGGCAGGTGC
GTGGCCCCGAATCGATGTGCGTGCACTTACGGCTTTACTGGACCCCAGTGTGAAAGAGAT
TACAGGACAGGTCCATGTTTTACTGTGATCAGCAACCAGATGTGCCAGGGACAGCTCAGC
GGGATTGTCTGCACGAAAACGCTCTGCTGTGCCACGGTCGGCCGTGCCTGGGGCCACCCC
TGTGAGATGTGTCCCGCCCAGCCCCACCCCTGTCGCCGCGGCTTCATTCCAAATATCCGC
ACAGGAGCTTGTCAAGATGTGGACGAATGCCAGGCCATCCCTGGGCTCTGTCAAGGAGGA
AATTGCATTAATACTGTTGGGTCTTTTGAGTGCAAATGCCCTGCTGGACACAAATTTAAT
GAAGTGTCACAAAAATGTGAAGATATTGACGAATGTAGCACTATTCCTGGAATCTGTGAT
GGGGGCGAATGTACGAACACAGTCAGCAGTTACTTTTGCAAATGTCCCCCTGGTTTTTAC
ACCTCTCCAGACGGTACCAGATGCATAGATGTCCGCCCAGGATACTGTTACACGGCTCTG
GCAAATGGGCGCTGTTCTAACCAGCTGCCACAGTCCATCACCAAGATGCAGTGCTGCTGT
GATGCCGGCCGGTGCTGGTCTCCGGGGGTCACGGTCGCCCCCGAGATGTGTCCCATCAGA
GCAACTGAGGATTTCAACAAGCTGTGCTCCGTCCCTATGGTAATTCCCGAGAGGCCAGGA
TATCCTCCTCCACCCCTTGGCCCCGTTCCTCCCGTTCAGCCTGTCCCTCCTGGCTTTCCT
CCTGGGCCTCAAATCATGATCCCTCGACCACCAGTGGAATATCCGTATCCATCGCGGGAA
CCACCAAGGGTGCTGCCAGTCAACGTCACTGATTACTGCCAGCTCTTTCGCTATCTCTGT
CAAAATGGACGCTGCATCCCAACCCCCGGGAGCTACCGGTGTGAGTGCAACAAAGGATTC
CAGCTGGACCTCCGTGGGGAGTGCATTGATGTTGATGAATGTGAGAAGAACCCTTGTGCT
GGTGGCGAGTGTATTAACACGCAGGGCTCTTACACCTGTCAGTGCCGACCTGGTTATCAG
AGCACACTCACGCGGACAGAGTGCCGAGACATTGATGAATGTTTACAGAATGGCCGTATC
TGTAATAATGGACGTTGTATCAACACGGATGGCAGTTTCCATTGTGTGTGTAATGCAGGA
TTTCACGTCACACGAGATGGGAAGAACTGTGAAGATATGGATGAATGCAGCATAAGGAAT
ATGTGCCTTAATGGAATGTGTATCAACGAAGATGGCAGTTTCAAATGTATTTGCAAACCT
GGATTTCAGCTGGCATCAGATGGGCGTTATTGTAAAGATATTAATGAGTGTGAAACCCTT
GGGATCTGCATGAACGGGCGTTGCGTCAACACTGATGGCTCCTACAGATGTGAATGCTTT
CCTGGACTGGCCGTGGGTCTGGACGGACGTGTGTGTGTTGACACACACATGCGGAGCACA
TGCTATGGTGGATACAAAAGAGGCCAGTGTGTCAAACCCTTGTTTGGTGCTGTTACCAAG
TCTGAATGCTGTTGTGCCAGCACTGAGTATGCTTTCGGGGAACCTTGCCAACCATGTCCT
TCACAGAATTCAGCGGAGTATCAGGCGCTCTGCAGCAGTGGGCCAGGAATAACGTCAGCA
GGCAGCGATATAAATGAATGTGCATTAGATCCTGATATTTGCCCAAATGGAATTTGTGAA
AATCTTCGTGGGACCTACAAATGTATATGCAATTCAGGATATGAAGTGGATTCAACTGGG
AAAAACTGTGTTGATATTAATGAATGTGTATTGAATAGTCTGCTTTGTGACAATGGACAA
TGTAGAAATACTCCTGGAAGTTTTGTCTGTACCTGCCCCAAGGGATTTATATACAAACCT
GAACTGAAAACCTGTGAAGACATCGATGAATGTGAATCAAGTCCTTGCATTAATGGAGTC
TGCAAGAACAGTCCGGGCTCTTTCATTTGTGAATGTTCTTCTGAAAGTACTTTGGATCCA
ACAAAAACCATCTGCATAGAAACCATTAAGGGCACTTGTTGGCAGACTGTCATCGATGGG
CGGTGTGAGATCAACATCAATGGAGCCACATTGAAGTCCCAGTGCTGTTCATCCCTTGGT
GCTGCCTGGGGGAGCCCATGCACCCCATGCCAAGTCGATCCCATATGTGGGAAAGGCTAT
TCAAGAATTAAAGGAACACAGTGTGAAGATATAGATGAATGTGAAGTGTTCCCAGGAGTC
TGCAAGAATGGCTTGTGTGTTAACTCCAAGGGATCATTTAAATGTCAGTGTCCCAGTGGG
ATGACTTTGGATGCCACAGGGAGGATTTGCCTAGATATCCGCCTGGAAACCTGCTTCCTG
AGGTACGAGGACGAGGAGTGCACCCTGCCCGTGGCTGGGCGCCACCGCATGGACGCCTGC
TGCTGCTCAGTCGGGGCAGCCTGGGGCACCGAGGAGTGTGAGGAGTGTCCCGTGAGAAAC
ACACCTGAGTACGAGGAGCTCTGTCCCAGAGGACCCGGATTCGCCACAAAAGAAATTACA
AATGGCAAACGTTTTTTCAAAGACATCAACGAGTGTAAGATGATTCCCAACCTGTGCACC
CACGGCAAGTGCAGGAACACCATTGGCAGCTTCAAGTGCAGGTGTGACAGCGGCTTTGCT
CTGGATTCTGAAGAAAGGAACTGCACAGACATCGACGAATGCCGCATATCCCCTGACCTC
TGTGGCCGAGGCCAGTGTGTGAACACCCCCGGGGACTTTGAGTGCAAGTGCGATGAAGGC
TATGAAAGCGGATTCATGATGATGAAGAACTGCATGGATATCGATGAGTGTCAGAGAGAT
CCGCTGTTGTGCCGAGGAGGCGTGTGCCTGAACACTGAGGGAAGTTACCGCTGTGAATGT
CCCCCTGGCCATCAGCTGGCCCCCAACATCTCGGCGTGTATAGACATCAACGAGTGTGAA
CTAAGTGCACACCTCTGCCCCCATGGCCGCTGCGTGAACCTCATAGGAAAGTACCAGTGT
GCCTGCAACCCTGGCTACCACTCTACCCCTGACAGGCTGTTTTGTGTTGACATTGATGAA
TGCAGCATAATGAACGGTGGCTGTGAGACCTTCTGCACAAACTCTGAAGGTAGCTACGAA
TGTAGCTGTCAGCCAGGATTTGCACTGATGCCTGACCAGAGGTCCTGCACAGACATTGAT
GAGTGTGAAGATAACCCCAATATCTGTGATGGTGGTCAGTGTACAAACATACCTGGAGAG
TACAGGTGCTTGTGTTATGATGGATTCATGGCATCTGAAGACATGAAGACTTGCGTAGAT
GTCAATGAATGTGACCTGAATCCAAATATCTGCCTAAGTGGAACCTGTGAAAACACCAAA
GGCTCATTTATCTGCCACTGTGATATGGGCTATTCAGGCAAAAAAGGAAAAACAGGCTGT
ACAGACATCAATGAATGTGAAATTGGAGCACACAACTGCGACAGACATGCTGTATGTACC
AACACAGCAGGAAGCTTCAAATGCAGCTGTAGCCCCGGGTGGATTGGAGATGGCATTAAG
TGCACTGACCTGGACGAATGCTCCAATGGAACCCACATGTGCAGCCAACATGCAGACTGC
AAGAACACCATGGGCTCCTACCGCTGCCTCTGCAAAGAGGGGTACACGGGCGATGGCTTC
ACTTGTACAGATCTTGATGAGTGCTCTGAGAATCTAAACCTGTGTGGCAACGGCCAGTGC
CTTAACGCCCCAGGAGGATACCGCTGTGAATGTGACATGGGCTTTGTGCCCAGTGCTGAT
GGGAAAGCCTGTGAAGATATCGATGAGTGCTCTCTTCCGAACATCTGTGTTTTTGGAACT
TGCCACAACCTCCCTGGCCTCTTCCGCTGTGAATGTGAGATCGGCTATGAACTGGACAGA
AGTGGTGGGAACTGCACAGACGTTAATGAATGCCTGGATCCAACCACGTGCATCAGTGGG
AACTGTGTCAATACTCCAGGCAGCTATACCTGTGACTGTCCACCCGATTTTGAGCTGAAT
CCAACTCGAGTTGGCTGTGTCGATACCCGCTCTGGAAACTGCTATTTGGATATCCGTCCT
CGGGGAGACAATGGAGATACAGCCTGCAGCAATGAAATTGGGGTTGGAGTGTCCAAGGCT
TCTTGCTGCTGCTCTCTGGGTAAAGCCTGGGGCACTCCTTGTGAGCTGTGCCCGCCTGTG
AACACATCTGAGTACAAAATTCTTTGTCCTGGAGGAGAAGGTTTTCGACCCAACCCTATC
ACCGTTATATTGGAAGATATTGATGAGTGCCAGGAGCTTCCAGGGTTGTGCCAAGGCGGG
AAATGTATCAATACCTTCGGCAGCTTCCAGTGCCGCTGTCCAACGGGCTACTACCTGAAT
GAAGATACCCGAGTGTGTGATGATGTGAATGAATGTGAAACTCCCGGAATCTGTGGTCCA
GGGACATGTTACAACACTGTTGGCAACTACACCTGTATCTGCCCTCCAGACTACATGCAA
GTGAATGGGGGGAATAATTGCATGGATATGAGGAGGAGTCTGTGCTACAGGAACTATTAT
GCTGACAACCAGACCTGCGATGGAGAACTGTTGTTCAACATGACCAAGAAGATGTGCTGT
TGTTCCTACAACATTGGCCGGGCCTGGAACAAGCCCTGTGAACAGTGCCCCATTCCAAGC
ACAGATGAATTTGCTACACTCTGTGGAAGTCAACGGCCAGGCTTTGTCATCGACATCTAT
ACCGGTTTACCTGTCGATATCGACGAGTGTCGGGAGATCCCAGGGGTCTGTGAAAACGGT
GTGTGTATCAACATGGTCGGCAGCTTCCGTTGTGAATGTCCAGTGGGCTTCTTCTATAAT
GACAAGTTGCTGGTTTGTGAAGACATTGACGAGTGTCAGAACGGCCCAGTGTGCCAGCGA
AACGCAGAGTGCATCAACACCGCGGGCAGCTACCGCTGTGATTGCAAACCCGGCTACCGA
TTCACCTCCACGGGGCAGTGCAATGATCGCAATGAATGTCAAGAAATCCCCAATATATGC
AGCCATGGACAGTGTATTGACACAGTTGGAAGCTTTTATTGCCTTTGCCACACTGGTTTT
AAAACAAACGCTGATCAAACCATGTGTTTGGACATAAATGAGTGTGAAAGAGATGCCTGT
GGGAATGGCACTTGCCGGAACACGATTGGTTCCTTCAACTGCCGCTGCAATCACGGTTTC
ATCCTTTCCCACAACAATGACTGCATAGATGTTGATGAATGTGCAACTGGAAATGGGAAC
CTTTGCAGAAATGGCCAGTGTATCAATACAGTGGGGTCCTTCCAGTGTCAGTGCAATGAA
GGCTATGAGGTGGCTCCAGATGGGAGAACCTGTGTGGATATCAATGAATGTCTCCTAGAT
CCCAGAAAATGTGCCCCAGGTACCTGTCAAAACTTGGATGGGTCCTACAGATGTATCTGT
CCACCTGGATACAGTCTCCAGAATGACAAGTGTGAAGATATTGATGAATGTGTTGAAGAG
CCAGAAATCTGTGCCTTGGGCACATGCAGTAACACTGAAGGCAGCTTCAAATGTCTGTGT
CCAGACGGGTTCTCCTTGTCCTCCACTGGAAGAAGGTGCCAAGATTTACGAATGAGCTAC
TGTTACGCGAAGTTTGAAGGAGGAAAGTGTTCATCACCCAAATCCAGAAATCACTCCAAA
CAGGAATGCTGCTGTGCCTTGAAGGGAGAAGGTTGGGGAGATCCCTGCGAGCTGTGCCCC
ACTGAACCCGATGAGGCCTTCCGCCAGATCTGTCCCTATGGAAGTGGCATCATCGTGGGA
CCTGATGATTCAGCAGTTGACATGGATGAGTGCAAAGAACCCGATGTCTGTAAACACGGG
CAGTGCATCAACACCGATGGGTCCTATCGCTGCGAATGTCCCTTTGGCTACATTCTGCAA
GGGAATGAATGTGTGGACACTGATGAATGTTCGGTAGGCAATCCTTGTGGAAATGGAACC
TGCAAGAATGTGATTGGAGGTTTCGAATGCACCTGTGAGGAGGGATTTGAGCCTGGGCCA
ATGATGACTTGTGAAGACATAAATGAGTGTGCCCAGAATCCTCTGCTCTGTGCCTTCCGC
TGTGTAAATACTTATGGGTCATATGAATGCAAGTGTCCTGCTGGATATGTTCTGAGAGAA
GACAGAAGGATGTGCAAAGATGAGGATGAGTGTGAAGAGGGAAAACACGACTGTGCTGAA
AAACAAATGGAGTGCAAGAACCTCATTGGCACATACCTCTGCATCTGTGGACCTGGGTAT
CAGCGAAGACCTGACGGAGAAGGCTGCGTAGATGAAAATGAATGTCAGACCAAGCCTGGG
ATCTGTGAGAACGGGCGCTGCCTCAACACCAGGGGGAGCTATACCTGCGAGTGCAATGAC
GGCTTTACAGCCAGCCCCAACCAGGATGAGTGCCTCGACAACCGAGAAGGGTACTGCTTC
ACGGAGGTGCTCCAGAACATGTGTCAGATCGGCTCAAGCAACAGGAACCCCGTCACTAAG
TCTGAATGCTGCTGCGATGGAGGGAGAGGCTGGGGGCCCCACTGTGAGATCTGCCCTTTC
CAGGGGACTGTGGCTTTCAAAAAACTCTGTCCCCATGGCCGAGGGTTTATGACCAATGGA
GCAGATATTGATGAATGCAAGGTTATTCATGATGTTTGCCGAAATGGGGAATGTGTCAAT
GACAGAGGATCATATCATTGCATTTGTAAAACTGGCTACACTCCAGATATAACTGGAACT
GCCTGTGTAGATCTAAATGAGTGCAACCAGGCTCCCAAACCCTGCAATTTCATCTGTAAG
AACACAGAAGGGAGTTACCAGTGTTCATGCCCGAAAGGCTACATTCTGCAGGAGGACGGA
AGGAGCTGCAAAGATCTTGATGAGTGTGCAACTAAGCAGCACAACTGCCAGTTCCTGTGT
GTTAACACCATTGGCAGCTTCACATGTAAATGTCCTCCTGGATTTACCCAACACCATACT
GCCTGCATTGATAACAATGAATGCACCTCTGACATCAACCTGTGTGGGTCAAAGGGCATT
TGCCAGAACACTCCTGGAAGCTTCACTTGTGAATGCCAGCGGGGATTCTCACTTGATCCG
ACCGGCGCCAGCTGTGAAGATGTGGACGAGTGTGAGGGAAACCATCGCTGCCAGCACGGC
TGCCAGAACATCATCGGCGGCTACAGGTGCAGCTGCCCCCAGGGCTATCTCCAGCACTAC
CAGTGGAACCAGTGTGTTGATGAAAATGAATGCCTCAGTGCTCACATCTGTGGAGGAGCC
TCCTGTCACAACACCCTGGGGAGCTACAAGTGCATGTGCCCTGCCGGCTTCCAATACGAA
CAGTTCAGTGGAGGTTGCCAAGACATCAACGAATGTGGCTCTGCTCAGGCCCCCTGCAGT
TATGGCTGTTCCAATACTGAGGGCGGCTACCTGTGTGCCTGTCCACCTGGCTACTTCCGA
ATAGGCCAAGGGCACTGTGTTTCTGGAATGGGCATGGGCCGGGGAAACCCAGAGCCACCT
GCCAGCGGTGAAATGGATGACAACTCACTCTCCCCAGAGGCTTGTTATGAGTGTAAGATC
AACGGCTACCCCAAACGCGGCAGGAAGCGGAGAAGCGCAAATGAAACAGATGCCTCCAAC
ATTGAGGATCAACCTGAGATAGAAGCCAATGTGAGTCTTGCAAGTTGGGATGTTGAGAAG
ACAGCCGTGTTCGCTTTCAATATTTCCCACATCAGTAACAAGGTCCGAATCCTAGAACTC
CTTCCAGCCCTCACGACTCTGACGAATCACAACAGATACTTGATTGAATCTGGAAATGAA
AACGGCTTCTTTAAAATCAACCAAAAGGAAGGGATCAGCTACCTCCACTTCACAAAGAAG
AAGCCAGTGGCTGGAACCTATTCATTACAAATCAGTAGTACTCCACTTTATAAAAAGAAA
GAACTTAATCAGCTAGAAGATAAATATGACAAAGACTACCTCAGTGGTGAACTGGGTGAT
AATCTGAAGATGAAAATTCAGATTTTGCTTCATTAA
Protein Properties
Number of Residues 2871
Molecular Weight 312249.0
Theoretical pI 4.56
Pfam Domain Function Not Available
Signals
  • 1-24
Transmembrane Regions
  • 214-234
  • 247-267
  • 280-300
  • 313-334
  • 349-369
  • 410-430
Protein Sequence
>Fibrillin-1
MRRGGLLEVALGFTVLLASYTSHGADTNLEAGNVKETRANRAKRRGGGGHNALKGPNVCG
SRYNAYCCPGWKTLPGGNQCIVPICRHSCGDGFCSRPNMCTCPSGQIAPSCGSRSIQHCN
IRCMNGGSCSDDHCLCQKGYIGTHCGQPVCESGCLNGGRCVAPNRCACTYGFTGPQCERD
YRTGPCFTVISNQMCQGQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIR
TGACQDVDECQAIPGLCQGGNCINTVGSFECKCPAGHKFNEVSQKCEDIDECSTIPGICD
GGECTNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALANGRCSNQLPQSITKMQCCC
DAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPERPGYPPPPLGPVPPVQPVPPGFP
PGPQIMIPRPPVEYPYPSREPPRVLPVNVTDYCQLFRYLCQNGRCIPTPGSYRCECNKGF
QLDLRGECIDVDECEKNPCAGGECINTQGSYTCQCRPGYQSTLTRTECRDIDECLQNGRI
CNNGRCINTDGSFHCVCNAGFHVTRDGKNCEDMDECSIRNMCLNGMCINEDGSFKCICKP
GFQLASDGRYCKDINECETLGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRST
CYGGYKRGQCVKPLFGAVTKSECCCASTEYAFGEPCQPCPSQNSAEYQALCSSGPGITSA
GSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLCDNGQ
CRNTPGSFVCTCPKGFIYKPELKTCEDIDECESSPCINGVCKNSPGSFICECSSESTLDP
TKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTPCQVDPICGKGY
SRIKGTQCEDIDECEVFPGVCKNGLCVNSKGSFKCQCPSGMTLDATGRICLDIRLETCFL
RYEDEECTLPVAGRHRMDACCCSVGAAWGTEECEECPVRNTPEYEELCPRGPGFATKEIT
NGKRFFKDINECKMIPNLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDL
CGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCLNTEGSYRCEC
PPGHQLAPNISACIDINECELSAHLCPHGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDE
CSIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCTDIDECEDNPNICDGGQCTNIPGE
YRCLCYDGFMASEDMKTCVDVNECDLNPNICLSGTCENTKGSFICHCDMGYSGKKGKTGC
TDINECEIGAHNCDRHAVCTNTAGSFKCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADC
KNTMGSYRCLCKEGYTGDGFTCTDLDECSENLNLCGNGQCLNAPGGYRCECDMGFVPSAD
GKACEDIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTDVNECLDPTTCISG
NCVNTPGSYTCDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKA
SCCCSLGKAWGTPCELCPPVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGG
KCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDYMQ
VNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPIPS
TDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENGVCINMVGSFRCECPVGFFYN
DKLLVCEDIDECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQCNDRNECQEIPNIC
SHGQCIDTVGSFYCLCHTGFKTNADQTMCLDINECERDACGNGTCRNTIGSFNCRCNHGF
ILSHNNDCIDVDECATGNGNLCRNGQCINTVGSFQCQCNEGYEVAPDGRTCVDINECLLD
PRKCAPGTCQNLDGSYRCICPPGYSLQNDKCEDIDECVEEPEICALGTCSNTEGSFKCLC
PDGFSLSSTGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEGWGDPCELCP
TEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRCECPFGYILQ
GNECVDTDECSVGNPCGNGTCKNVIGGFECTCEEGFEPGPMMTCEDINECAQNPLLCAFR
CVNTYGSYECKCPAGYVLREDRRMCKDEDECEEGKHDCAEKQMECKNLIGTYLCICGPGY
QRRPDGEGCVDENECQTKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDNREGYCF
TEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNG
ADIDECKVIHDVCRNGECVNDRGSYHCICKTGYTPDITGTACVDLNECNQAPKPCNFICK
NTEGSYQCSCPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGSFTCKCPPGFTQHHT
ACIDNNECTSDINLCGSKGICQNTPGSFTCECQRGFSLDPTGASCEDVDECEGNHRCQHG
CQNIIGGYRCSCPQGYLQHYQWNQCVDENECLSAHICGGASCHNTLGSYKCMCPAGFQYE
QFSGGCQDINECGSAQAPCSYGCSNTEGGYLCACPPGYFRIGQGHCVSGMGMGRGNPEPP
ASGEMDDNSLSPEACYECKINGYPKRGRKRRSANETDASNIEDQPEIEANVSLASWDVEK
TAVFAFNISHISNKVRILELLPALTTLTNHNRYLIESGNENGFFKINQKEGISYLHFTKK
KPVAGTYSLQISSTPLYKKKELNQLEDKYDKDYLSGELGDNLKMKIQILLH
GenBank ID Protein AAA74122.1
UniProtKB/Swiss-Prot ID P98133
UniProtKB/Swiss-Prot Entry Name FBN1_BOVIN
PDB IDs
GenBank Gene ID L28748
GeneCard ID FBN1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available