Identification
BMDB Protein ID BMDBP02766
Secondary Accession Numbers None
Name Fibulin-1
Synonyms Not Available
Gene Name FBLN1
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 5
Locus Not Available
SNPs FBLN1
Gene Sequence
>2121 bp
ATGGAGCGCGCCGCCCCGTCGCGCCGGGTCCCGCTGCTGCTGCTGCTGCTCGGCGGCCTC
TCGCTGCTGGCGGCCCCAGCGGGCGCAGACGTCTCCATGGAGGCCTGCTGTGCAGATGGA
CATCGAATGGCCACCGAGCACAGGGCCTGCTCGCTGCCCTACACCTCGGAATCCAAGGAA
TGCAGGATGGTTCAGGAGCAATGTTGCCAGAACCAGCTGGAGGAGCTGCACTGCGCCACG
GGCATCAACCTGGCCAACGAGCAGGACAGCTGCGCCACACCACGCGGCGACAACACCAGC
CTCGAGGCCATGTTCGTGAAGAGGTGCTGCCATTGCTGCCTACTGGGGCGGGCAGCCCAG
GCCCAGGGCCAGAGCTGTGAGTACAGCCTCATGGTTGGCTACCAGTGCGGGCTGGTCTTC
CGGGCGTGCTGCGTCAAGGGCCAGGAGACGGCAGACTTTGCCCCGGGGGACGGCGGGGAC
CTCCAAGAAACAGCTAAGGTTTCTGAGATCGAGGAGGAACAAGAGGACCCCTACCTGAAT
GACCGCTGCCGAGGCGGCGGGCCCTGCAAACAGCAATGCCGGGACACGGGGGAGGAAGTT
GTCTGCTCCTGCTTTGTGGGGTACCAGCTGCTCCCCGACGGCGTCTCCTGTGAAGATGTC
AACGAGTGCATCACGGGCGGCCAGAGCTGCCGGCTCGGGGAAACCTGCGTCAACACAGCG
GGCTCCTTCCGCTGCCAGCGCGACAGCAGCTGCGGAACTGGCTATGAGCTCACAGAGGAC
AATGACTGCAAAGATATTGACGAGTGTGAGAGTGGTATTCATAACTGCCTCCCCGATTTT
ATCTGTCAGAATACTCTGGGATCCTTCCGCTGCAGACCCAAGCTACAGTGCAAGAGTGGC
TTTATACAAGATGCTCTAGGCAACTGTATTGATATCAATGAGTGTTTGAGTATCAGTGCC
CCATGCCCTGTTGGGCAGACGTGCATCAACACAGAGGGCTCCTACACGTGCCAGAAGAAC
GTGCCCAACTGTGGCCGTGGCTACCATCTCAACGAGGAGGGAACCCGCTTCGTTGATGTG
GACGAGTGCTCTCCCCCCTCTGAGCCCTGTGGGCCGGGGCACCTGTGTGTGAACTCCCCT
GGAAGTTTCCGCTGTGAGTGCAAAGCCGGGTACTACTTCGACGGCATCAGCAGGACATGT
GTGGACATCAACGAGTGCCGGCGGTACCCAGGGCGCCTGTGCGGCCACAAGTGCGAGAAC
ACGCCCGGCTCCTACTACTGCAGCTGCACCCTGGGCTTCCGGCTCTCCTCCGACGGCCGC
TCCTGTGAAGACGTGAACGAGTGTAACAGCAACCCCTGCAGCCAGGAGTGTGCCAACGTC
TACGGCTCCTACCAGTGTTACTGCCGGCGAGGCTACCAGCTCAGCGACGTGGACGGGGTC
ACCTGCGAAGACATCGACGAGTGCGCCCTGCCCACGGGGGGCCACATCTGCTCCTACCGC
TGCATCAACATCCCTGGGAGCTTCCAGTGCAGCTGCCCCCCGACCGGCTACCGGCTGGCC
CCCAACGGTCGCAACTGCCAAGACATCGATGAGTGTGTGACCGGCATCCACAACTGCTCC
ATCAACGAGACCTGCTTCAACATCCAGGGCAGCTTCCGCTGCCTGGCCTTCGAGTGTCCC
GAGAACTACCGCCGCTCCACAGACGCGCTCCGCCAAGAGAAGACAGATACTGTCCGCTGC
ATCAAGTCCTGCCGCCCCAACGATGTCGCCTGCGTGCTGGACCCGGTGCACACCATCTCC
CACACCGTCGTCTCACTCCCCACCTTCCGCGAGTTCACCCGCCCCGAAGAGATCATCTTC
CTCCGGGCCATCACGCCTGCGTATCCTGCCAACCACGCGGACATCATCTTCGACATAACG
GATGGGAACCTCCGTGACTCTTTCGACATCATCAAGCGCTACATGGACGGCATGACTGTG
GGCGTCGTGCGCCAGGTGCGGCCCATCGTGGGCCCGTTCCACGCCGTCCTGAAGCTGGAG
ATGAACTACGTGGTTGGGGGTGTGGTATCGCACCGGAATGTCGTCAGCGTCCACATCTTC
GTCTCTGAGTACTGGTTCTGA
Protein Properties
Number of Residues 706
Molecular Weight 77530.0
Theoretical pI 4.69
Pfam Domain Function Not Available
Signals
  • 1-29
Transmembrane Regions
  • 46-69
Protein Sequence
>FBLN1 protein
MERAAPSRRVPLLLLLLGGLSLLAAPAGADVSMEACCADGHRMATEHRACSLPYTSESKE
CRMVQEQCCQNQLEELHCATGINLANEQDSCATPRGDNTSLEAMFVKRCCHCCLLGRAAQ
AQGQSCEYSLMVGYQCGLVFRACCVKGQETADFAPGDGGDLQETAKVSEIEEEQEDPYLN
DRCRGGGPCKQQCRDTGEEVVCSCFVGYQLLPDGVSCEDVNECITGGQSCRLGETCVNTA
GSFRCQRDSSCGTGYELTEDNDCKDIDECESGIHNCLPDFICQNTLGSFRCRPKLQCKSG
FIQDALGNCIDINECLSISAPCPVGQTCINTEGSYTCQKNVPNCGRGYHLNEEGTRFVDV
DECSPPSEPCGPGHLCVNSPGSFRCECKAGYYFDGISRTCVDINECRRYPGRLCGHKCEN
TPGSYYCSCTLGFRLSSDGRSCEDVNECNSNPCSQECANVYGSYQCYCRRGYQLSDVDGV
TCEDIDECALPTGGHICSYRCINIPGSFQCSCPPTGYRLAPNGRNCQDIDECVTGIHNCS
INETCFNIQGSFRCLAFECPENYRRSTDALRQEKTDTVRCIKSCRPNDVACVLDPVHTIS
HTVVSLPTFREFTRPEEIIFLRAITPAYPANHADIIFDITDGNLRDSFDIIKRYMDGMTV
GVVRQVRPIVGPFHAVLKLEMNYVVGGVVSHRNVVSVHIFVSEYWF
GenBank ID Protein AAI40669.1
UniProtKB/Swiss-Prot ID A5D7S8
UniProtKB/Swiss-Prot Entry Name A5D7S8_BOVIN
PDB IDs Not Available
GenBank Gene ID BC140668
GeneCard ID FBLN1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available