| Identification |
|---|
| BMDB Protein ID
| BMDBP02799 |
| Secondary Accession Numbers
| None |
| Name
| Calsyntenin-3 |
| Synonyms
|
Not Available
|
| Gene Name
| CLSTN3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| CLSTN3 |
| Gene Sequence
|
>2586 bp
ATGACCCCCTTGCTGTTTCCCCTCTTGCTGGCCTCCCTGCTCCCCTCCAGCTCCTGTAAC
AAAGCCAACAAGCACAAGCCATGGATTGAGGCAGAATACCAAGGCATCGTCATGGAGAAT
GACAACACGGTCCTGCTGAACCCACCGCTCTTTGCCTTGGACAAGGATGCTCCCTTGCGC
TATGCAGGTGAGATCTGTGGCTTCCGGCTCCATGGGTCCGGGGTGCCCTTTGAGGCTGTG
ATCCTGGACAAAGCGACAGGAGAAGGGCTGATCCGGGCCAAGGAGCCGGTGGACTGCGAG
GCCCAGAAGGAGCACACCTTCACCATCCAGGCCTACGACTGCGGCGAGGGCCCGGATGGG
GCCAACACCAAGAAGTCCCACAAGGCCACCGTACATGTGCGGGTCAACGACGTGAACGAG
TTTGCCCCGGTGTTTGTGGAGCGGCTGTATCGCGCGGCAGTGACCGAGGGGAAGCTGTAT
GACCGCATCCTTCGGGTGGAGGCCATTGATGGCGACTGCTCCCCCCAGTACAGCCAGATC
TGCTATTACGAGATCCTCACACCCAATACCCCCTTCCTCATCGACAATGACGGGAACATT
GAGAACACGGAGAAGCTACAGTACAGTGGTGAGAAGCTCTACAAGTTCACAGTGACGGCT
TATGACTGCGGGAAGAAGCGGGCGGCGGACGATGCTGAGGTGGAGATCCAGGTGAAGCCC
ACCTGTAAACCCAGCTGGCAAGGCTGGAACAAAAGGATTGAATATGCACCAGGCGCCGGG
AGCTTGGCTCTGTTCCCTGGTATCCGCCTGGAGACCTGTGATGAACCTCTCTGGAACATT
CAGGCCACCATAGAGCTGCAGACCAGCCATGTGGCCAAGGGCTGTGACCGTGACAACTAC
TCAGAGCGTGCACTGCGGAAACTCTGCGGCGCAGCCCCCGGGGAGGTGGATCTACTGCCC
ATGCCTGGCCCCAATGCCAACTGGACGGCGGGCCTCTCGGTGCACTACAGCCAGGACAGC
AGCCTCATCTACTGGTTCAATGGCACCCAGGCGGTGCAGGTGCCCCTGGGGGGCGCTGCG
GGGCTGGGCTCCGGGCCCCCGGACAGCCTCAGTGACCACTTTACCCTGTCCTTCTGGATG
AAGCACGGTGTCACTCCCAACAAGGGCAAGAAGGAAGAGGAAACCATCGTGTGTAACACC
GTCCAGAACGAGGACGGCTTCTCTCACTACTCACTGACTGTCCACGGCTGCAGAATTGCC
TTCCTCTACTGGCCTCTGCTTGAGAGTGCCCGGCCAGTCAAATTCCTCTGGAAGCTGGAG
CAGGTCTGCGATGACGAGTGGCACCACTATGCTTTGAATCTCGAGTTCCCCACGGTCACA
CTCTATGCAGATGGCATCTCCTTCGACCCCGCCCTCATCCACGACAATGGTCTCATCCAC
CCGCCTCGAAGGGAGCCTGCGCTCATGATTGGGGCCTGCTGGGCTGAGGAGAAGAACAAA
GAGAAGGAAAAGGGAGGTGACAACAGTACGGACGCCACAGCAGGAGACCCCTTGCCGATC
CACCACTACTTCCACGGCTACCTGGCTGGTTTCAGCGTGCGCTCAGGCCGCCTGGAGAGC
CGTGAGGTCATCGAGTGCCTCTATGCATGTCGGGAGGGGCTGGACTATAGGGATTTCGAG
AGCCTGGGCAAAGGCATGAAGGTCCACGTGAACCCCTCGCAGTCCCTGCTCACCCTGGAG
GGGGATGATGTGGAGACCTTCAACCATGCCCTGCAGCATGTGGCTTACATGAACACTCTG
CGCTTTGCCACGCCTGGCGTCAGGCCCCTGCGCCTCACCACTGCCGTCAAGTGCTTCAGT
GAAGAGTCCTGTGTCTCCATCCCTGAAGTGGAGGGCTATGTGGTGGTGCTACAGCCGGAT
GCCCCCCAGATCCTGCTGAGCGGCACTGCTCACTTTGCCCGCCCAGCTGTGGACTTCGAG
GGACCCGAGGGGGTTCCTTTGTTCCCTGACCTCCAGATCACTTGCTCCATTTCTCACCAG
GTGGAGGCCAAAAAGGACGAGAGTTGGCAAGGCACGGTGACAGACACTCGCATGTCAGAC
GAGATCGTGCACAACCTGGACGGCTGTGAGATCTCCCTGGTGGGGGATGACCTGGATCCC
GAGCGGGAAAGTCTGCTCCTGGACATGGCATCCTTGCAGCAGCGAGGCCTGGAGCTCACC
AACACATCTGCCTACCTCACCATTGCCGGGGTGGAGAGCATCACCGTGTACGAAGAGATC
CTGAGGCAGGCGCGTTATCGCCTGCGACATGGAGCAGCCCTCTACGCCAGGAAGTTCCGG
CTCTCCTGCTCAGAAATGAATGGGCGTTACTCCAGCAATGAATTCATCGTGGAGTGGTTC
CCAGTGCGGCGACCCTCATCATCGTGGTGTGCGTGGGCTTCCTGGTGCTCATGGTCGTCC
TGGGTCTCGTGCGCATTCACTCACTGCACCGCCGCGTCTCGGGGGCCAGTGGGCCTCCCG
GGGCCTCCAGCGACCCCAAGGATCCCGATCTCTTCTGGGATGACTCAGCTCTCACCATTA
TCGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 957 |
| Molecular Weight
| 105795.0 |
| Theoretical pI
| 5.08 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Calsyntenin-3
MTPLLFPLLLASLLPSSSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLR
YAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDG
ANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQI
CYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKP
TCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNY
SERALRKLCGAAPGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGAA
GLGSGPPDSLSDHFTLSFWMKHGVTPNKGKKEEETIVCNTVQNEDGFSHYSLTVHGCRIA
FLYWPLLESARPVKFLWKLEQVCDDEWHHYALNLEFPTVTLYADGISFDPALIHDNGLIH
PPRREPALMIGACWAEEKNKEKEKGGDNSTDATAGDPLPIHHYFHGYLAGFSVRSGRLES
REVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTL
RFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQILLSGTAHFARPAVDFE
GPEGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDP
ERESLLLDMASLQQRGLELTNTSAYLTIAGVESITVYEEILRQARYRLRHGAALYARKFR
LSCSEMNGRYSSNEFIVEVSVLHSVNRVAHPSHMLSSQQFLHRGHQPPPEMAGHSLASSH
RNSMVPSAATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGASGPPGASSDPKDPDLFWDD
SALTIIVNPMESYQSRQVCVAGAAGGQQDDEDSSDSEAADSPSSDERRIIETPPHRY
|
| External Links |
|---|
| GenBank ID Protein
| AAI20083.1 |
| UniProtKB/Swiss-Prot ID
| Q0VCN6 |
| UniProtKB/Swiss-Prot Entry Name
| CSTN3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC120082 |
| GeneCard ID
| CLSTN3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
