Identification
BMDB Protein ID BMDBP02813
Secondary Accession Numbers None
Name Calmegin
Synonyms Not Available
Gene Name CLGN
Protein Type Enzyme
Biological Properties
General Function Involved in calcium ion binding
Specific Function Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 17
Locus Not Available
SNPs CLGN
Gene Sequence
>1821 bp
ATGCGTTTCCAAGGCTTTTGGCTATGTTTGGGTCTTCTTTTCATCTCAGTTAATGCAGAA
TTTATGGATGATAGTGTTGAGATGGAAGACTTTGATGAAAATTCAGAAGAGACTGATGAA
CTCTCCTCAGAGATTAAATATAAGACACCTCAACCTGTAGGAGAAGTGTATTTTACAGAA
ACTTTTGATAGTGGAAGGCTGGCTGGGTGGGTATTATCAAAAGCAAAGAAAGATGATATA
GATGCGGAGATTTCTATATATGATGGAAGATGGGAAATAGAAGAATTGAAAGAAAATCGA
ATACCTGGTGATCGAGGACTGGTGTTGAAATCTAGAGCAAAGCATCATGCAATATCTGCT
GTGTTAGCAAAACCCTTCATCTTTGCTGATAAACCTCTGGTAGTTCAATATGAAGTAAAT
TTTCAAGATGGTATTGATTGTGGAGGTGCATACATTAAACTCCTAGCAGACACTGATGGT
TTGAATCTGGAAAATTTCTATGATAAAACATCCTATACCATTATGTTTGGGCCAGATAAA
TGTGGAGAAGATTATAAACTTCATTTTATCTTCAGACATAAACATCCCAAAACTGGAGTT
TTTGAAGAAAAACATGCCAAACCTCCAGATGTAGACCTTAAAAGGTTCTTCACAGACAGG
AAGACTCATCTTTATACCCTTGTGATGAATCCAGATGACACATTTGAAGTATTAATTGAT
CAGATAGTTGTAAACAAAGGAAGCCTACTAGAGGATGTGGTTCCTCCTATCAATCCTCCC
AAAGAAATTGAAGATCCCACTGATGAAAAACCTGATGATTGGGATGAAAGAGCAAAAATC
CCTGATGCTTCTGCTGTCAAACCAGAAGACTGGGATGAAAGTGAACCTCCCCAAATAGTA
GATTCAAGTGCTGTTAAACCTGATGGCTGGCTTGATAATGAACCGGAATTTATTCCTGAT
CCTAATGCTGAGAAACCCTTTGACTGGAATGAAGACATGGATGGAGAATGGGAGGCACCT
CATATTTCTAACCCAGCATGTCGGATTGGGTGTGGTGAATGGAGCCCTCCCATGATAGAT
AACCCGAAATACAAAGGAATATGGAGACCGCCAATGATAGATAACCCTAACTACCAGGGT
ATCTGGAGTCCTCGAAAAATTCCTAATCCAGATTATTTTGAAGACAATCACCCATTTCTT
CTGACTTCTTTCCGTGCTCTTGGTTTAGAGCTTTGGTCCATGACCTCTGATATCTACTTT
GATAATTTTATTATCTGTTCAGAAAAGGAAGTAGCAGACCGCTGGGCTGCAGATGGTTGG
GGAATGAAGATACTGATAGAAAATGCTAATGAGCCTAGTATATTCAAACAATTGATGTCA
GCTACTGAACAGCGCCCGTGGCTTTGGTTCATTTACCTCTTGACAGCAGCACTTCCAATA
GCATTAATTGGTTCATTTTGTTGGCCAAGAAAAGTAAAGAAAAAATATGAAGATGTGGCT
TTCGAAAAACTGGACATATGTAAACCACAAACAAAGGGAGCACTGGAGCAGGAAGTGAAG
GAAGAGAAGGCAGCCCTGGAGAAGCCAGTTGACTTGGAAGAGGAAAAAAAGCAAAGTGAT
GGTGAAATTGTTGAAAAAGAAGAGGAAGGTGAACCTGAGGAAAAGAGTGAAGAAGAAATT
GAAATTATAGAAGGACAAGAAGAAGGCAATAAATCCAATAAGTCTGGATCAGAGGATGAG
ATGAAAGAGGCAGATGAGAGCACAGGATCTGGAGATGGGCCAATAAAGTCAGTACGCAAA
AGAAGAGTACGGAAGGAGTAA
Protein Properties
Number of Residues 606
Molecular Weight 69515.0
Theoretical pI 4.27
Pfam Domain Function Not Available
Signals
  • 1-19
Transmembrane Regions
  • 467-487
Protein Sequence
>Calmegin
MRFQGFWLCLGLLFISVNAEFMDDSVEMEDFDENSEETDELSSEIKYKTPQPVGEVYFTE
TFDSGRLAGWVLSKAKKDDIDAEISIYDGRWEIEELKENRIPGDRGLVLKSRAKHHAISA
VLAKPFIFADKPLVVQYEVNFQDGIDCGGAYIKLLADTDGLNLENFYDKTSYTIMFGPDK
CGEDYKLHFIFRHKHPKTGVFEEKHAKPPDVDLKRFFTDRKTHLYTLVMNPDDTFEVLID
QIVVNKGSLLEDVVPPINPPKEIEDPTDEKPDDWDERAKIPDASAVKPEDWDESEPPQIV
DSSAVKPDGWLDNEPEFIPDPNAEKPFDWNEDMDGEWEAPHISNPACRIGCGEWSPPMID
NPKYKGIWRPPMIDNPNYQGIWSPRKIPNPDYFEDNHPFLLTSFRALGLELWSMTSDIYF
DNFIICSEKEVADRWAADGWGMKILIENANEPSIFKQLMSATEQRPWLWFIYLLTAALPI
ALIGSFCWPRKVKKKYEDVAFEKLDICKPQTKGALEQEVKEEKAALEKPVDLEEEKKQSD
GEIVEKEEEGEPEEKSEEEIEIIEGQEEGNKSNKSGSEDEMKEADESTGSGDGPIKSVRK
RRVRKE
GenBank ID Protein AAI03402.1
UniProtKB/Swiss-Prot ID Q3SYT6
UniProtKB/Swiss-Prot Entry Name CLGN_BOVIN
PDB IDs Not Available
GenBank Gene ID BC103401
GeneCard ID CLGN
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available