Showing Protein Phosphatidylserine synthase 1 (BMDBP02841)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 138 metabolites
Identification
BMDB Protein ID BMDBP02841
Secondary Accession Numbers
  • BMDBP03100
Name Phosphatidylserine synthase 1
Synonyms Not Available
Gene Name PTDSS1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (By similarity).
Pathways Not Available
Reactions
Phosphatidylcholine + L-Serine → an L-1-Phosphatidylserine + Choline details
PC(14:0/14:0) + L-Serine → Choline + PS(14:0/14:0) details
PC(14:0/14:1(9Z)) + L-Serine → Choline + PS(14:0/14:1(9Z)) details
PC(14:0/16:0) + L-Serine → Choline + PS(14:0/16:0) details
PC(14:0/16:1(9Z)) + L-Serine → Choline + PS(14:0/16:1(9Z)) details
PC(14:0/18:0) + L-Serine → Choline + PS(14:0/18:0) details
PC(14:0/18:1(9Z)) + L-Serine → Choline + PS(14:0/18:1(9Z)) details
PC(14:0/18:2(9Z,12Z)) + L-Serine → Choline + PS(14:0/18:2(9Z,12Z)) details
PC(14:0/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(14:0/18:3(9Z,12Z,15Z)) details
PC(14:0/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(14:0/20:3(8Z,11Z,14Z)) details
PC(14:0/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(14:0/20:4(5Z,8Z,11Z,14Z)) details
PC(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(14:1(9Z)/14:1(9Z)) + L-Serine → Choline + PS(14:1(9Z)/14:1(9Z)) details
PC(14:1(9Z)/16:0) + L-Serine → Choline + PS(14:1(9Z)/16:0) details
PC(14:1(9Z)/16:1(9Z)) + L-Serine → Choline + PS(14:1(9Z)/16:1(9Z)) details
PC(14:1(9Z)/18:0) + L-Serine → Choline + PS(14:1(9Z)/18:0) details
PC(14:1(9Z)/18:1(9Z)) + L-Serine → Choline + PS(14:1(9Z)/18:1(9Z)) details
PC(14:1(9Z)/18:2(9Z,12Z)) + L-Serine → Choline + PS(14:1(9Z)/18:2(9Z,12Z)) details
PC(14:1(9Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(14:1(9Z)/18:3(9Z,12Z,15Z)) details
PC(14:1(9Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(14:1(9Z)/20:3(8Z,11Z,14Z)) details
PC(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(16:0/16:1(9Z)) + L-Serine → Choline + PS(16:0/16:1(9Z)) details
PC(16:0/18:0) + L-Serine → Choline + PS(16:0/18:0) details
PC(16:0/18:1(11Z)) + L-Serine → Choline + PS(16:0/18:1(11Z)) details
PC(16:0/18:1(9Z)) + L-Serine → Choline + PS(16:0/18:1(9Z)) details
PC(16:0/18:2(9Z,12Z)) + L-Serine → Choline + PS(16:0/18:2(9Z,12Z)) details
PC(16:0/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(16:0/18:3(6Z,9Z,12Z)) details
PC(16:0/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(16:0/18:3(9Z,12Z,15Z)) details
PC(16:0/20:0) + L-Serine → Choline + PS(16:0/20:0) details
PC(16:0/20:1(11Z)) + L-Serine → Choline + PS(16:0/20:1(11Z)) details
PC(16:0/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(16:0/20:3(8Z,11Z,14Z)) details
PC(16:0/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(16:0/20:4(5Z,8Z,11Z,14Z)) details
PC(16:0/22:0) + L-Serine → Choline + PS(16:0/22:0) details
PC(16:0/22:1(13Z)) + L-Serine → Choline + PS(16:0/22:1(13Z)) details
PC(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(16:1(9Z)/16:1(9Z)) + L-Serine → Choline + PS(16:1(9Z)/16:1(9Z)) details
PC(16:1(9Z)/18:0) + L-Serine → Choline + PS(16:1(9Z)/18:0) details
PC(16:1(9Z)/18:1(9Z)) + L-Serine → Choline + PS(16:1(9Z)/18:1(9Z)) details
PC(16:1(9Z)/18:2(9Z,12Z)) + L-Serine → Choline + PS(16:1(9Z)/18:2(9Z,12Z)) details
PC(16:1(9Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(16:1(9Z)/18:3(9Z,12Z,15Z)) details
PC(16:1(9Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(16:1(9Z)/20:3(8Z,11Z,14Z)) details
PC(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(18:0/18:0) + L-Serine → Choline + PS(18:0/18:0) details
PC(18:0/18:1(11Z)) + L-Serine → Choline + PS(18:0/18:1(11Z)) details
PC(18:0/18:1(9Z)) + L-Serine → Choline + PS(18:0/18:1(9Z)) details
PC(18:0/18:2(9Z,12Z)) + L-Serine → Choline + PS(18:0/18:2(9Z,12Z)) details
PC(18:0/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(18:0/18:3(6Z,9Z,12Z)) details
PC(18:0/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:0/18:3(9Z,12Z,15Z)) details
PC(18:0/20:0) + L-Serine → Choline + PS(18:0/20:0) details
PC(18:0/20:1(11Z)) + L-Serine → Choline + PS(18:0/20:1(11Z)) details
PC(18:0/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(18:0/20:3(8Z,11Z,14Z)) details
PC(18:0/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(18:0/20:4(5Z,8Z,11Z,14Z)) details
PC(18:0/20:4(8Z,11Z,14Z,17Z)) + L-Serine → Choline + PS(18:0/20:4(8Z,11Z,14Z,17Z)) details
PC(18:0/22:0) + L-Serine → Choline + PS(18:0/22:0) details
PC(18:0/22:1(13Z)) + L-Serine → Choline + PS(18:0/22:1(13Z)) details
PC(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(18:0/22:5(7Z,10Z,13Z,16Z,19Z)) details
PC(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(18:1(11Z)/18:1(11Z)) + L-Serine → Choline + PS(18:1(11Z)/18:1(11Z)) details
PC(18:1(11Z)/18:2(9Z,12Z)) + L-Serine → Choline + PS(18:1(11Z)/18:2(9Z,12Z)) details
PC(18:1(11Z)/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(18:1(11Z)/18:3(6Z,9Z,12Z)) details
PC(18:1(11Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:1(11Z)/18:3(9Z,12Z,15Z)) details
PC(18:1(11Z)/20:0) + L-Serine → Choline + PS(18:1(11Z)/20:0) details
PC(18:1(11Z)/20:1(11Z)) + L-Serine → Choline + PS(18:1(11Z)/20:1(11Z)) details
PC(18:1(11Z)/22:0) + L-Serine → Choline + PS(18:1(11Z)/22:0) details
PC(18:1(11Z)/22:1(13Z)) + L-Serine → Choline + PS(18:1(11Z)/22:1(13Z)) details
PC(18:1(9Z)/18:1(9Z)) + L-Serine → Choline + PS(18:1(9Z)/18:1(9Z)) details
PC(18:1(9Z)/18:2(9Z,12Z)) + L-Serine → Choline + PS(18:1(9Z)/18:2(9Z,12Z)) details
PC(18:1(9Z)/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(18:1(9Z)/18:3(6Z,9Z,12Z)) details
PC(18:1(9Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:1(9Z)/18:3(9Z,12Z,15Z)) details
PC(18:1(9Z)/20:0) + L-Serine → Choline + PS(18:1(9Z)/20:0) details
PC(18:1(9Z)/20:1(11Z)) + L-Serine → Choline + PS(18:1(9Z)/20:1(11Z)) details
PC(18:1(9Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(18:1(9Z)/20:3(8Z,11Z,14Z)) details
PC(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(18:1(9Z)/22:0) + L-Serine → Choline + PS(18:1(9Z)/22:0) details
PC(18:1(9Z)/22:1(13Z)) + L-Serine → Choline + PS(18:1(9Z)/22:1(13Z)) details
PC(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(18:2(9Z,12Z)/18:2(9Z,12Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/18:2(9Z,12Z)) details
PC(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) details
PC(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)) details
PC(18:2(9Z,12Z)/20:0) + L-Serine → Choline + PS(18:2(9Z,12Z)/20:0) details
PC(18:2(9Z,12Z)/20:1(11Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/20:1(11Z)) details
PC(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)) details
PC(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(18:2(9Z,12Z)/22:0) + L-Serine → Choline + PS(18:2(9Z,12Z)/22:0) details
PC(18:2(9Z,12Z)/22:1(13Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/22:1(13Z)) details
PC(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) details
PC(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)) details
PC(18:3(6Z,9Z,12Z)/20:0) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/20:0) details
PC(18:3(6Z,9Z,12Z)/20:1(11Z)) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/20:1(11Z)) details
PC(18:3(6Z,9Z,12Z)/22:0) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/22:0) details
PC(18:3(6Z,9Z,12Z)/22:1(13Z)) + L-Serine → Choline + PS(18:3(6Z,9Z,12Z)/22:1(13Z)) details
PC(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) details
PC(18:3(9Z,12Z,15Z)/20:0) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/20:0) details
PC(18:3(9Z,12Z,15Z)/20:1(11Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/20:1(11Z)) details
PC(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)) details
PC(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(18:3(9Z,12Z,15Z)/22:0) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/22:0) details
PC(18:3(9Z,12Z,15Z)/22:1(13Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/22:1(13Z)) details
PC(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(20:0/20:0) + L-Serine → Choline + PS(20:0/20:0) details
PC(20:0/20:1(11Z)) + L-Serine → Choline + PS(20:0/20:1(11Z)) details
PC(20:0/22:0) + L-Serine → Choline + PS(20:0/22:0) details
PC(20:0/22:1(13Z)) + L-Serine → Choline + PS(20:0/22:1(13Z)) details
PC(20:1(11Z)/20:1(11Z)) + L-Serine → Choline + PS(20:1(11Z)/20:1(11Z)) details
PC(20:1(11Z)/22:0) + L-Serine → Choline + PS(20:1(11Z)/22:0) details
PC(20:1(11Z)/22:1(13Z)) + L-Serine → Choline + PS(20:1(11Z)/22:1(13Z)) details
PC(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) + L-Serine → Choline + PS(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)) details
PC(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) + L-Serine → Choline + PS(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)) details
PC(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
PC(22:0/22:0) + L-Serine → Choline + PS(22:0/22:0) details
PC(22:0/22:1(13Z)) + L-Serine → Choline + PS(22:0/22:1(13Z)) details
PC(22:1(13Z)/22:1(13Z)) + L-Serine → Choline + PS(22:1(13Z)/22:1(13Z)) details
PC(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) + L-Serine → Choline + PS(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 14
Locus Not Available
SNPs PTDSS1
Gene Sequence Not Available
Protein Properties
Number of Residues 473
Molecular Weight 55416.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 36-56
  • 73-93
  • 103-123
  • 187-207
  • 217-237
  • 287-307
  • 320-342
  • 356-376
  • 384-404
Protein Sequence Not Available
GenBank ID Protein AAI12834.1
UniProtKB/Swiss-Prot ID Q2KHY9
UniProtKB/Swiss-Prot Entry Name PTSS1_BOVIN
PDB IDs Not Available
GenBank Gene ID DAAA02039445
GeneCard ID PTDSS1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available