| Identification |
|---|
| BMDB Protein ID
| BMDBP02949 |
| Secondary Accession Numbers
| None |
| Name
| Synaptojanin-1 |
| Synonyms
|
Not Available
|
| Gene Name
| SYNJ1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis (By similarity). Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (PubMed:9199318). |
| Pathways
|
Not Available
|
| Reactions
|
| Inositol 1,3,4,5-tetraphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Hydrogen phosphate |
details
|
| Inositol 1,3,4,5-tetraphosphate + Water → Inositol 1,3,4-trisphosphate + Hydrogen phosphate |
details
|
| Inositol 1,4,5-trisphosphate + Water → 1D-Myo-inositol 1,4-bisphosphate + Hydrogen phosphate |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| SYNJ1 |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 1324 |
| Molecular Weight
| 146584.0 |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| BAA21652.1 |
| UniProtKB/Swiss-Prot ID
| O18964 |
| UniProtKB/Swiss-Prot Entry Name
| SYNJ1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| D85682 |
| GeneCard ID
| SYNJ1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
