Identification
BMDB Protein ID BMDBP03008
Secondary Accession Numbers None
Name DnaJ homolog subfamily B member 11
Synonyms Not Available
Gene Name DNAJB11
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 1
Locus Not Available
SNPs DNAJB11
Gene Sequence Not Available
Protein Properties
Number of Residues 358
Molecular Weight 40504.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • 1-22
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein AAI03471.1
UniProtKB/Swiss-Prot ID Q3ZBA6
UniProtKB/Swiss-Prot Entry Name DJB11_BOVIN
PDB IDs Not Available
GenBank Gene ID BC103470
GeneCard ID DNAJB11
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available