Identification
BMDB Protein ID BMDBP03122
Secondary Accession Numbers None
Name Long-chain fatty acid transport protein 1
Synonyms Not Available
Gene Name SLC27A1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
Pathways Not Available
Reactions
Phytanic acid + Adenosine triphosphate + Coenzyme A → Phytanoyl-CoA + ADP + Pyrophosphate details
3a,7a-Dihydroxycoprostanic acid + Adenosine triphosphate + Coenzyme A → 3a,7a-Dihydroxy-5b-cholestanoyl-CoA + Pyrophosphate + 3'-AMP details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs SLC27A1
Gene Sequence Not Available
Protein Properties
Number of Residues 646
Molecular Weight 71123.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 14-34
Protein Sequence Not Available
GenBank ID Protein AAW68434.1
UniProtKB/Swiss-Prot ID Q3ZKN0
UniProtKB/Swiss-Prot Entry Name S27A1_BOVIN
PDB IDs Not Available
GenBank Gene ID AY738459
GeneCard ID SLC27A1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available