Showing Protein Glypican-1 (BMDBP03178)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP03178 |
| Secondary Accession Numbers |
|
| Name | Glypican-1 |
| Synonyms | Not Available |
| Gene Name | GPC1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Not Available |
| Specific Function | Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN (C) to PRNP (Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | Not Available |
| Locus | Not Available |
| SNPs | GPC1 |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 559 |
| Molecular Weight | 61007.0 |
| Theoretical pI | Not Available |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence | Not Available |
| External Links | |
| GenBank ID Protein | AAI05497.1 |
| UniProtKB/Swiss-Prot ID | G3X745 |
| UniProtKB/Swiss-Prot Entry Name | GPC1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | DAAA02009500 |
| GeneCard ID | GPC1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |