Showing Protein UDP-glucose 4-epimerase (BMDBP03192)
| Identification | |||||
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| BMDB Protein ID | BMDBP03192 | ||||
| Secondary Accession Numbers |
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| Name | UDP-glucose 4-epimerase | ||||
| Synonyms | Not Available | ||||
| Gene Name | GALE | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Not Available | ||||
| Specific Function | Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids. | ||||
| Pathways | Not Available | ||||
| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | Not Available | ||||
| Locus | Not Available | ||||
| SNPs | GALE | ||||
| Gene Sequence | Not Available | ||||
| Protein Properties | |||||
| Number of Residues | 348 | ||||
| Molecular Weight | 38254.0 | ||||
| Theoretical pI | Not Available | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence | Not Available | ||||
| External Links | |||||
| GenBank ID Protein | AAI02186.2 | ||||
| UniProtKB/Swiss-Prot ID | Q3T105 | ||||
| UniProtKB/Swiss-Prot Entry Name | GALE_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | DAAA02006426 | ||||
| GeneCard ID | GALE | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||