You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Bovine Metabolome Database.
Showing metabocard for Chitobiose (BMDB0003556)
| Record Information | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Version | 1.0 | ||||||||||||||||
| Creation Date | 2016-09-30 23:05:18 UTC | ||||||||||||||||
| Update Date | 2020-05-21 16:28:28 UTC | ||||||||||||||||
| BMDB ID | BMDB0003556 | ||||||||||||||||
| Secondary Accession Numbers |
| ||||||||||||||||
| Metabolite Identification | |||||||||||||||||
| Common Name | Chitobiose | ||||||||||||||||
| Description | Chitobiose, also known as CBS or chitobiose, belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group. Chitobiose is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Chitobiose can be converted into N-acetyl-D-glucosamine; which is mediated by the enzyme Beta-hexosaminidase subunit alpha. In cattle, chitobiose is involved in the metabolic pathway called the amino sugar metabolism pathway. Chitobiose is a potentially toxic compound. | ||||||||||||||||
| Structure |  | ||||||||||||||||
| Synonyms |
| ||||||||||||||||
| Chemical Formula | C15H26N2O12 | ||||||||||||||||
| Average Molecular Weight | 426.3731 | ||||||||||||||||
| Monoisotopic Molecular Weight | 426.148574306 | ||||||||||||||||
| IUPAC Name | Not Available | ||||||||||||||||
| Traditional Name | Not Available | ||||||||||||||||
| CAS Registry Number | 577-76-4 | ||||||||||||||||
| SMILES | Not Available | ||||||||||||||||
| InChI Identifier | InChI=1S/C15H26N2O12/c1-4(20)16-7-11(23)12(6(3-19)27-13(7)24)29-14-8(17-15(25)26)10(22)9(21)5(2-18)28-14/h5-14,17-19,21-24H,2-3H2,1H3,(H,16,20)(H,25,26)/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14+/m1/s1 | ||||||||||||||||
| InChI Key | HSRZMOSQMYFZBL-CGKOVJDHSA-N | ||||||||||||||||
| Chemical Taxonomy | |||||||||||||||||
| Description | belongs to the class of organic compounds known as acylaminosugars. These are organic compounds containing a sugar linked to a chain through N-acyl group. | ||||||||||||||||
| Kingdom | Organic compounds | ||||||||||||||||
| Super Class | Organic oxygen compounds | ||||||||||||||||
| Class | Organooxygen compounds | ||||||||||||||||
| Sub Class | Carbohydrates and carbohydrate conjugates | ||||||||||||||||
| Direct Parent | Acylaminosugars | ||||||||||||||||
| Alternative Parents |
| ||||||||||||||||
| Substituents |
| ||||||||||||||||
| Molecular Framework | Aliphatic heteromonocyclic compounds | ||||||||||||||||
| External Descriptors | Not Available | ||||||||||||||||
| Ontology | |||||||||||||||||
| Status | Expected but not Quantified | ||||||||||||||||
| Origin |
| ||||||||||||||||
| Biofunction | Not Available | ||||||||||||||||
| Application | Not Available | ||||||||||||||||
| Cellular locations |
| ||||||||||||||||
| Physical Properties | |||||||||||||||||
| State | Solid | ||||||||||||||||
| Experimental Properties |
| ||||||||||||||||
| Predicted Properties | Not Available | ||||||||||||||||
| Spectra | |||||||||||||||||
| Spectra |
| ||||||||||||||||
| Biological Properties | |||||||||||||||||
| Cellular Locations |
| ||||||||||||||||
| Biospecimen Locations |
| ||||||||||||||||
| Pathways |
| ||||||||||||||||
| Normal Concentrations | |||||||||||||||||
| |||||||||||||||||
| Abnormal Concentrations | |||||||||||||||||
| Not Available | |||||||||||||||||
| External Links | |||||||||||||||||
| HMDB ID | HMDB0003556 | ||||||||||||||||
| DrugBank ID | Not Available | ||||||||||||||||
| Phenol Explorer Compound ID | Not Available | ||||||||||||||||
| FooDB ID | FDB023196 | ||||||||||||||||
| KNApSAcK ID | Not Available | ||||||||||||||||
| Chemspider ID | 17216232 | ||||||||||||||||
| KEGG Compound ID | C01674 | ||||||||||||||||
| BioCyc ID | CHITOBIOSE | ||||||||||||||||
| BiGG ID | Not Available | ||||||||||||||||
| Wikipedia Link | Chitobiose | ||||||||||||||||
| METLIN ID | 6953 | ||||||||||||||||
| PubChem Compound | 22833609 | ||||||||||||||||
| PDB ID | Not Available | ||||||||||||||||
| ChEBI ID | Not Available | ||||||||||||||||
| References | |||||||||||||||||
| Synthesis Reference | Cottaz, Sylvain; Samain, Eric. Genetic engineering of Escherichia coli for the production of NI,NII-diacetylchitobiose (chitinbiose) and its utilization as a primer for the synthesis of complex carbohydrates. Metabolic Engineering (2005), 7(4), 311-317. | ||||||||||||||||
| Material Safety Data Sheet (MSDS) | Not Available | ||||||||||||||||
| General References | Not Available | ||||||||||||||||
Enzymes
- General function:
- Involved in cation binding
- Specific function:
- Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding (By similarity).
- Gene Name:
- CHIA
- Uniprot ID:
- Q95M17
- Molecular weight:
- 52129.0
Reactions
| Chitin → Chitobiose | details |