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Record Information
Version1.0
Creation Date2016-09-30 23:39:11 UTC
Update Date2020-05-21 16:26:45 UTC
BMDB IDBMDB0007529
Secondary Accession Numbers
  • BMDB07529
Metabolite Identification
Common NameDG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0)
DescriptionDG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0), also known as dg(20:4(5z,8z,11z,14z)/24:1(15z)/0:0) or DG(20:4/24:1), belongs to the class of organic compounds known as 1,2-dg(20:4(5z,8z,11z,14z)/24:1(15z)/0:0)s. These are dg(20:4(5z,8z,11z,14z)/24:1(15z)/0:0)s containing a glycerol acylated at positions 1 and 2. DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) participates in a number of enzymatic reactions, within cattle. In particular, CDP-Ethanolamine and DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) can be converted into cytidine monophosphate and PE(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)) through the action of the enzyme choline/ethanolaminephosphotransferase. In addition, DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) can be biosynthesized from PA(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)); which is mediated by the enzyme phosphatidate phosphatase. In cattle, DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) is involved in a couple of metabolic pathways, which include phosphatidylethanolamine biosynthesis pe(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)) pathway and de novo triacylglycerol biosynthesis TG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/24:1(15Z)) pathway.
Structure
Thumb
Synonyms
ValueSource
Diacylglycerol(20:4/24:1)HMDB
DG(20:4/24:1)HMDB
DAG(20:4/24:1)HMDB
DiglycerideHMDB
DG(44:5)HMDB
DiacylglycerolHMDB
Diacylglycerol(44:5)HMDB
1-Arachidonoyl-2-nervonoyl-sn-glycerolHMDB
1-(5Z,8Z,11Z,14Z-Eicosatetraenoyl)-2-(15Z-tetracosanoyl)-sn-glycerolHMDB
DAG(44:5)HMDB
DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0)Lipid Annotator
Chemical FormulaC47H82O5
Average Molecular Weight727.151
Monoisotopic Molecular Weight726.616225734
IUPAC Name(2S)-1-hydroxy-3-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyloxy]propan-2-yl (15Z)-tetracos-15-enoate
Traditional Namediacylglycerol
CAS Registry NumberNot Available
SMILES
[H][C@](CO)(COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)OC(=O)CCCCCCCCCCCCC\C=C/CCCCCCCC
InChI Identifier
InChI=1S/C47H82O5/c1-3-5-7-9-11-13-15-17-19-21-22-23-24-26-28-30-32-34-36-38-40-42-47(50)52-45(43-48)44-51-46(49)41-39-37-35-33-31-29-27-25-20-18-16-14-12-10-8-6-4-2/h12,14,17-20,27,29,33,35,45,48H,3-11,13,15-16,21-26,28,30-32,34,36-44H2,1-2H3/b14-12-,19-17-,20-18-,29-27-,35-33-/t45-/m0/s1
InChI KeyYFAFVULQEQGYAK-OXGRNNGBSA-N
Chemical Taxonomy
Description belongs to the class of organic compounds known as 1,2-diacylglycerols. These are diacylglycerols containing a glycerol acylated at positions 1 and 2.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassGlycerolipids
Sub ClassDiradylglycerols
Direct Parent1,2-diacylglycerols
Alternative Parents
Substituents
  • 1,2-acyl-sn-glycerol
  • Fatty acid ester
  • Fatty acyl
  • Dicarboxylic acid or derivatives
  • Carboxylic acid ester
  • Carboxylic acid derivative
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Primary alcohol
  • Organooxygen compound
  • Carbonyl group
  • Alcohol
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External DescriptorsNot Available
Ontology
StatusExpected but not Quantified
Origin
  • Endogenous
  • Exogenous
BiofunctionNot Available
ApplicationNot Available
Cellular locations
  • Cell membrane
  • Membrane
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP15.53ChemAxon
pKa (Strongest Acidic)14.58ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area72.83 ŲChemAxon
Rotatable Bond Count41ChemAxon
Refractivity228.49 m³·mol⁻¹ChemAxon
Polarizability93.62 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
Spectra
Spectrum TypeDescriptionSplash Key
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0006-0000000900-aa684ea5cc6c399a8aa0View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-08t9-0009900900-892a5657a08ffee6c340View in MoNA
Predicted LC-MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-03r3-0009900900-644b2cf0ceaa8176c9aaView in MoNA
Biological Properties
Cellular Locations
  • Cell membrane
  • Membrane
Biospecimen Locations
  • All Tissues
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
All TissuesExpected but not QuantifiedNot QuantifiedNot SpecifiedNot SpecifiedNormal
  • Not Applicable
details
Abnormal Concentrations
Not Available
HMDB IDHMDB0007529
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDNot Available
KNApSAcK IDNot Available
Chemspider IDNot Available
KEGG Compound IDNot Available
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkNot Available
METLIN IDNot Available
PubChem Compound53478307
PDB IDNot Available
ChEBI IDNot Available
References
Synthesis ReferenceNot Available
Material Safety Data Sheet (MSDS)Not Available
General ReferencesNot Available

Enzymes

General function:
Involved in ethanolaminephosphotransferase activity
Specific function:
Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the foramtion of phosphatidylethanolamine via 'Kennedy' pathway (By similarity).
Gene Name:
SELENOI
Uniprot ID:
Q17QM4
Molecular weight:
45214.0
Reactions
CDP-Ethanolamine + DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0) → Cytidine monophosphate + PE(20:4(5Z,8Z,11Z,14Z)/24:1(15Z))details