You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on Bovine Metabolome Database.
Showing metabocard for PE-NMe(16:0/16:0) (BMDB0010567)
Record Information | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Version | 1.0 | |||||||||||||||
Creation Date | 2016-10-03 18:09:24 UTC | |||||||||||||||
Update Date | 2020-05-21 16:26:16 UTC | |||||||||||||||
BMDB ID | BMDB0010567 | |||||||||||||||
Secondary Accession Numbers |
| |||||||||||||||
Metabolite Identification | ||||||||||||||||
Common Name | PE-NMe(16:0/16:0) | |||||||||||||||
Description | PE-NMe(16:0/16:0) is a monomethylphosphatidylethanolamine. It is a glycerophospholipid, and is formed by sequential methylation of phosphatidylethanolamine as part of a mechanism for biosynthesis of phosphatidylcholine. Monomethylphosphatidylethanolamines are usually found at trace levels in animal or plant tissues. They can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. PE-NMe(16:0/16:0), in particular, consists of two hexadecanoyl chain at positions C-1 and C2. Fatty acids containing 16, 18 and 20 carbons are the most common. Phospholipids, are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. | |||||||||||||||
Structure | ||||||||||||||||
Synonyms |
| |||||||||||||||
Chemical Formula | C38H76NO8P | |||||||||||||||
Average Molecular Weight | 705.9857 | |||||||||||||||
Monoisotopic Molecular Weight | 705.530854925 | |||||||||||||||
IUPAC Name | Not Available | |||||||||||||||
Traditional Name | Not Available | |||||||||||||||
CAS Registry Number | Not Available | |||||||||||||||
SMILES | Not Available | |||||||||||||||
InChI Identifier | InChI=1S/C38H76NO8P/c1-4-6-8-10-12-14-16-18-20-22-24-26-28-30-37(40)44-34-36(35-46-48(42,43)45-33-32-39-3)47-38(41)31-29-27-25-23-21-19-17-15-13-11-9-7-5-2/h36,39H,4-35H2,1-3H3,(H,42,43)/t36-/m1/s1 | |||||||||||||||
InChI Key | QSBINWBNXWAVAK-PSXMRANNSA-N | |||||||||||||||
Chemical Taxonomy | ||||||||||||||||
Description | belongs to the class of organic compounds known as monomethylphosphatidylethanolamines. These are lipids with a structure containing a glycerol moiety linked at its terminal C3 atom to a N-methylphosphoethanolamine group, and at its C1 and C2 terminal atoms by an acyl group. | |||||||||||||||
Kingdom | Organic compounds | |||||||||||||||
Super Class | Lipids and lipid-like molecules | |||||||||||||||
Class | Glycerophospholipids | |||||||||||||||
Sub Class | Glycerophosphoethanolamines | |||||||||||||||
Direct Parent | Monomethylphosphatidylethanolamines | |||||||||||||||
Alternative Parents | ||||||||||||||||
Substituents |
| |||||||||||||||
Molecular Framework | Aliphatic acyclic compounds | |||||||||||||||
External Descriptors |
| |||||||||||||||
Ontology | ||||||||||||||||
Status | Expected but not Quantified | |||||||||||||||
Origin |
| |||||||||||||||
Biofunction | Not Available | |||||||||||||||
Application | Not Available | |||||||||||||||
Cellular locations |
| |||||||||||||||
Physical Properties | ||||||||||||||||
State | Solid | |||||||||||||||
Experimental Properties |
| |||||||||||||||
Predicted Properties | Not Available | |||||||||||||||
Spectra | ||||||||||||||||
Spectra |
| |||||||||||||||
Biological Properties | ||||||||||||||||
Cellular Locations |
| |||||||||||||||
Biospecimen Locations | Not Available | |||||||||||||||
Pathways |
| |||||||||||||||
Normal Concentrations | ||||||||||||||||
Not Available | ||||||||||||||||
Abnormal Concentrations | ||||||||||||||||
Not Available | ||||||||||||||||
External Links | ||||||||||||||||
HMDB ID | HMDB0010567 | |||||||||||||||
DrugBank ID | Not Available | |||||||||||||||
Phenol Explorer Compound ID | Not Available | |||||||||||||||
FooDB ID | FDB027717 | |||||||||||||||
KNApSAcK ID | Not Available | |||||||||||||||
Chemspider ID | 7825981 | |||||||||||||||
KEGG Compound ID | Not Available | |||||||||||||||
BioCyc ID | Not Available | |||||||||||||||
BiGG ID | Not Available | |||||||||||||||
Wikipedia Link | Not Available | |||||||||||||||
METLIN ID | Not Available | |||||||||||||||
PubChem Compound | 9547031 | |||||||||||||||
PDB ID | Not Available | |||||||||||||||
ChEBI ID | Not Available | |||||||||||||||
References | ||||||||||||||||
Synthesis Reference | Not Available | |||||||||||||||
Material Safety Data Sheet (MSDS) | Not Available | |||||||||||||||
General References | Not Available |
Enzymes
- General function:
- Involved in phosphatidylethanolamine N-methyltransferas
- Specific function:
- Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC).
- Gene Name:
- PEMT
- Uniprot ID:
- Q7YRH6
- Molecular weight:
- 22018.0
Reactions
S-Adenosylmethionine + PE(16:0/16:0) → S-Adenosylhomocysteine + PE-NMe(16:0/16:0) | details |
PE-NMe(16:0/16:0) + S-Adenosylmethionine → PE-NMe2(16:0/16:0) + S-Adenosylhomocysteine | details |