Showing Protein Steroid 21-hydroxylase (BMDBP00060)
| Identification | |||||||||
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| BMDB Protein ID | BMDBP00060 | ||||||||
| Secondary Accession Numbers | None | ||||||||
| Name | Steroid 21-hydroxylase | ||||||||
| Synonyms | Not Available | ||||||||
| Gene Name | CYP21 | ||||||||
| Protein Type | Enzyme | ||||||||
| Biological Properties | |||||||||
| General Function | Secondary metabolites biosynthesis, transport and catabolism | ||||||||
| Specific Function | Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. | ||||||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||||||
| Cellular Location | Not Available | ||||||||
| Gene Properties | |||||||||
| Chromosome Location | 23 | ||||||||
| Locus | Not Available | ||||||||
| SNPs | CYP21 | ||||||||
| Gene Sequence |
>1491 bp CCTCTGCCTGGGTCTCCAGCCATGGTCCTCGCAGGGCTGCTGCTGCTGCTGACCCTGCTC AGTGGCGCTCACCTGCTATGGGGCCGGTGGAAGCTCAGAAACCTCCACCTCCCACCTCTG GTCCCCGGCTTCCTGCACCTGCTGCAGCCCAACCTCCCCATCCATCTGCTGAGCCTGACT CAGAAACTCGGGCCTGTCTACAGGCTTCGCCTTGGGCTGCAAGAGGTGGTGGTGCTGAAC TCCAAGAGGACCATTGAGGAGGCTATGATCAGGAAGTGGGTGGACTTTGCCGGCAGACCC CAGATACCATCCTACAAGTTGGTGTCTCAGCGCTGCCAGGACATCTCTCTGGGGGACTAC TCTCTGCTCTGGAAGGCCCACAAGAAACTCACCCGCTCAGCCTTGCTGCTGGGCACCCGC AGCTCCATGGAGCCCTGGGTGGACCAGCTGACCCAGGAGTTCTGCGAGCGCATGAGAGTC CAGGCCGGTGCCCCCGTGACCATCCAGAAGGAATTCTCTCTGCTTACCTGCAGCATCATC TGTTACCTCACTTTTGGAAACAAGGAGGACACCTTAGTACATGCCTTTCACGACTGTGTT CAGGACTTGATGAAGACCTGGGACCACTGGTCCATCCAGATTTTGGACATGGTTCCTTTT CTCAGGTTCTTCCCCAACCCTGGGCTCTGGAGGCTGAAGCAGGCCATAGAGAACAGGGAC CACATGGTGGAGAAGCAGCTGACGCGCCACAAGGAGAGCATGGTGGCCGGCCAGTGGAGG GATATGACGGACTACATGCTCCAGGGGGTAGGGAGGCAAAGAGTAGAAGAGGGCCCCGGA CAGCTCCTGGAAGGACACGTGCACATGTCTGTGGTGGACCTTTTCATCGGGGGCACTGAA ACCACGGCGAGCACCCTCTCCTGGGCTGTGGCGTTCCTACTTCACCACCCCGAGATTCAG CGCCGCCTTCAGGAGGAGTTGGATCGCGAGCTGGGCCCCGGAGCCTCATGCTCCCGAGTC ACTTACAAGGACCGCGCTCGGCTGCCTCTGCTCAACGCCACCATCGCGGAGGTGCTGCGC CTGCGGCCGGTCGTGCCCCTGGCCTTGCCTCACCGCACCACGCGGCCTAGCAGCATCTTC GGCTACGACATCCCTGAGGGCATGGTCGTTATCCCCAACCTCCAAGGTGCCCACCTGGAC GAGACCGTCTGGGAGCAGCCGTACGAGTTCCGGCCGGACCGCTTCCTGGAGCCGGGCGCG AACCCCAGCGCGCTGGCATTTGGCTGCGGGGCGCGCGTGTGCCTGGGCGAGTCGCTGGCG CGCCTGGAGCTGTTCGTGGTGCTCCTGCGACTGCTGCAGGCCTTCACGCTGCTGCCGCCG CCCGTGGGCGCCCTGCCGTCGCTGCAGCCGGATCCCTACTGCGGTGTCAACCTCAAGGTC CAGCCTTTCCAGGTGCGGCTGCAGCCCCGGGGGGTGGAGGCCGGGGCCTGG |
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| Protein Properties | |||||||||
| Number of Residues | 496 | ||||||||
| Molecular Weight | 56077.0 | ||||||||
| Theoretical pI | 8.34 | ||||||||
| Pfam Domain Function | Not Available | ||||||||
| Signals |
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| Transmembrane Regions | Not Available | ||||||||
| Protein Sequence |
>Steroid 21-hydroxylase MVLAGLLLLLTLLAGAHLLWGRWKLRNLHLPPLVPGFLHLLQPNLPIHLLSLTQKLGPVY RLRLGLQEVVVLNSKRTIEEAMIRKWVDFAGRPQIPSYKLVSQRCQDISLGDYSLLWKAH KKLTRSALLLGTRSSMEPWVDQLTQEFCERMRVQAGAPVTIQKEFSLLTCSIICYLTFGN KEDTLVHAFHDCVQDLMKTWDHWSIQILDMVPFLRFFPNPGLWRLKQAIENRDHMVEKQL TRHKESMVAGQWRDMTDYMLQGVGRQRVEEGPGQLLEGHVHMSVVDLFIGGTETTASTLS WAVAFLLHHPEIQRRLQEELDRELGPGASCSRVTYKDRARLPLLNATIAEVLRLRPVVPL ALPHRTTRPSSIFGYDIPEGMVVIPNLQGAHLDETVWEQPHEFRPDRFLEPGANPSALAF GCGARVCLGESLARLELFVVLLRLLQAFTLLPPPVGALPSLQPDPYCGVNLKVQPFQVRL QPRGVEAGAWESASAQ |
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| External Links | |||||||||
| GenBank ID Protein | AAA83247.1 | ||||||||
| UniProtKB/Swiss-Prot ID | P00191 | ||||||||
| UniProtKB/Swiss-Prot Entry Name | CP21A_BOVIN | ||||||||
| PDB IDs | |||||||||
| GenBank Gene ID | M11267 | ||||||||
| GeneCard ID | CYP21 | ||||||||
| GenAtlas ID | Not Available | ||||||||
| HGNC ID | Not Available | ||||||||
| References | |||||||||
| General References | Not Available | ||||||||