Bovine Metabolome Database: Showing Protein Hepatic triacylglycerol lipase (BMDBP00235)

Identification Biological properties Gene properties Protein properties External links References XML Show 7 metabolites

Identification

BMDB Protein ID

BMDBP00235

Secondary Accession Numbers

None

Name

Hepatic triacylglycerol lipase

Synonyms

Not Available

Gene Name

LIPC

Protein Type

Enzyme

Biological Properties

General Function

Involved in heparin binding

Specific Function

Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin (By similarity).

Pathways

Glycerolipid Metabolism

Reactions

TG(16:0/16:0/16:0)[iso] + Water → DG(16:0/16:0/0:0) + Palmitic acid	details
DG(16:0/16:0/0:0) + Water → Palmitic acid + MG(0:0/16:0/0:0)	details
MG(0:0/16:0/0:0) + Water → Glycerol + Palmitic acid	details

GO Classification

Not Available

Cellular Location

Not Available

Gene Properties

Chromosome Location

Locus

Not Available

SNPs

LIPC

Gene Sequence

>1503 bp
ATGGAAAATCCCCTGTGTGTCTCTATCTTCTTGTTTTACTGCATCTTGATCCAATCAAGT
GCCCATGGACAAAGCCTGGGACCAGAGTCATTTGGAAGGAGATCTCGAGCTGCTGAAACA
AACAAAACACCGCAGGAGACAAGAACCAAATTTCTGCTCTTTAGAGGAGAAACCGATAAG
GGCTGTCAGATTCTGCTCAATCACTCAGACACGTTACAGCAATGTGGCTTCAACTCCTCG
CTGCCGCTGGTGATGATAGTCCACGGGTGGTTGGTGGACGACATACTGGAAGACTGGGTC
TGGGAGATGGTAGCTGCACTGAAGTCTCAGCTGGCCCAGTCAGTGAATGTGGGGCTGGCA
GAATGGGTCACCCTGGCTCACAACCACTACACCACTGCCGTCCGCAACACTCGCCTCGTC
GGCCAGGAGATCGCAGCTCTTCTCCAGTGGCTGCAGGAATCTGTTCAATTTTCTCCAAGC
CATGTTCATCTAATTGGGTACAGCCTGGGTGCACATGTCTCAGGATTCGCTGGCAGTTAC
ATGAGCAGAAAGCACAAGATTGGAAGAATTACAGGGCTGGACGCCGCAGGCCCTTTGTTT
GAAAAAGCCTCCCTCAGTGACCGGCTTTCACCAGATGATGCCAATTTTGTGGACGCCATT
CACACCTTTACCTGGGAGCACATGGGCCTGAGTGTGGGCATGAAACAGCCCATAGCACAC
TATGACTTCTACCCCAATGGGGGTTCCTACCAGCCTGGATGCCACTTCCTAGAGCTCTAC
AAACATTTCGCCAAGCATGGCTTAAATGCCATCACCCGGACTGTCAAATGTGCCCATGAG
CGGTCAGTGCACCTCTTCATTGACTCCTTGCTGCACGCTGACATGCAGAGCATGGCCTAC
CTGTGCAGAGACATGGACCGCTTCAGCCAAGGCCTGTGTCTGAGCTGCAAGAAGGGTCGT
TGCAACACACTAGGCTACCACACCCGCCAGGAGCGGCAAAGCAAGAAGAGCAAGAGCCTC
TTCCTGGTGACTCGAGCCCAGTCCCCATTCAAAGTTTATCATTACCAGTTCAAGATTCGG
TTCATCAACCAAACTGAGAACCCTGTAGAACCAACTTTCACCGTGTCATTCCTCGGAACA
AGAGGGGAGAGGCAGAAGATCCCCATCACTCTGAGCAAAGGAATTACTAGTAATGAAACC
TATTCCTTTCTAATAACATTGGATGTGGATATTGGGGAACTGATCATGATCAAGTTCAAG
TGGGAAAACCGCATGGTGTGGTCCAATGTCTGGAATACGGTCCAAACCATCATCCCCTGG
GGAAGAGGGTCCCTTCACTCAGGCCTTGCTCTGAAGAGCATCAGAGTCAAAGTGGGAGAA
ACACAGCAAAGAATGACATTTTGCTCAGAAAACATGAATGATCTACTACTTCACCCAGCC
CGGGAGAAAACCTTTGTGAGATGTGAAGCAAACTCTGAAACACTGAAACGAAAGATCAGA
TGA

Protein Properties

Number of Residues

500

Molecular Weight

56826.0

Theoretical pI

9.1

Pfam Domain Function

Not Available

Signals

1-23

Transmembrane Regions

Not Available

Protein Sequence

>Hepatic triacylglycerol lipase
MENPLCVSIFLFYCILIQSSAHGQSLGPESFGRRSRAAETNKTPQETRTKFLLFRGETDK
GCQILLNHSDTLQQCGFNSSLPLVMIVHGWLVDDILEDWVWEMVAALKSQLAQSVNVGLA
EWVTLAHNHYTTAVRNTRLVGQEIAALLQWLQESVQFSPSHVHLIGYSLGAHVSGFAGSY
MSRKHKIGRITGLDAAGPLFEKASLSDRLSPDDANFVDAIHTFTWEHMGLSVGMKQPIAH
YDFYPNGGSYQPGCHFLELYKHFAKHGLNAITRTVKCAHERSVHLFIDSLLHADMQSMAY
LCRDMDRFSQGLCLSCKKGRCNTLGYHTRQERQSKKSKSLFLVTRAQSPFKVYHYQFKIR
FINQTENPVEPTFTVSFLGTRGERQKIPITLSKGITSNETYSFLITLDVDIGELIMIKFK
WENRMVWSNVWNTVQTIIPWGRGSLHSGLALKSIRVKVGETQQRMTFCSENMNDLLLHPA
REKTFVRCEANSETLKRKIR

External Links

GenBank ID Protein

AAI03073.1

UniProtKB/Swiss-Prot ID

Q3SZ79

UniProtKB/Swiss-Prot Entry Name

LIPC_BOVIN

PDB IDs

Not Available

GenBank Gene ID

BC103072

GeneCard ID