Identification |
BMDB Protein ID
| BMDBP00360 |
Secondary Accession Numbers
| None |
Name
| Arylamine N-acetyltransferase 1 |
Synonyms
|
Not Available
|
Gene Name
| NAT1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Secondary metabolites biosynthesis, transport and catabolism |
Specific Function
| Participates in the detoxification of a plethora of hydrazine and arylamine drugs. |
Pathways
|
Not Available
|
Reactions
|
Paraxanthine + Acetyl-CoA → 5-Acetylamino-6-formylamino-3-methyluracil + Coenzyme A |
details
|
|
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 27 |
Locus
| Not Available |
SNPs
| NAT1 |
Gene Sequence
|
>873 bp
ATGGACATTGACGCATATTTTGAAAGAATTGGTTATAAGAACTCGAGGGACAAATTGGAC
TTGGAAACATTAACTGACATTCTTCAGCATCAGATCCGAGCCATTCCCTTTGAGAACCTT
AACATCCACTGTGGGGAAGCCATGGAATTGGACTTAGAGGTCATTTTTGATCAAATTGTG
AGGAGGAAACGGGGTGGGTGGTGTCTCCAAGTCAACCACCTTCTGTACTGGGCCCTGACC
ATGATCGGTTTTGAGACCACCATACTGGGAGGGTATGTGTACAACACATTCAACGACAAA
TACAGCAGCGCCATGATCCACCTCCTGCTGAAGGTGACCATCGACGGCAGGGACTACATA
GCTGATGCTGGGTTTGGGCGCTCTTACCAGATGTGGCAGCCTCTCGAGTTAATTTCTGGG
AAGTACCAGCCCCAGACGCCTTGCATCTTCCGCTTGACTGAAGACAGAGGAACCTGGTAC
CTGGACCAAATCAGAAGAGAGCAGTACATCCCAAACCAAGACTTTCTGGATTCTGACCTC
TTGGAAAAGAATGAGTATCGGAAAATCTACTCTTTTACTCTTGAACCTCGAACAATTAAA
GACTTTGAGTCTGTGAATACATACCTTCAAGAGTCTCCAGCATCTGTGTTTACAAGCAAG
TCATTTTGCTCCTTGCAGACCCCAGAAGGTGTTCATTGCTTAGTGGGTTTCACCCTCACC
TACAGGAGATTCAATTATAAGGACAATACAGATTTGGTAGAGTTTAAGACACTGAATGAG
AAAGAAATAGAAGAAAATCTAAAAAACATATTTAATATTTCCTTGGAGAAAAAGCTTACC
CCCAAACATGGTGATAAATTTTTTACCATTTAG
|
Protein Properties |
Number of Residues
| 290 |
Molecular Weight
| 34199.0 |
Theoretical pI
| 5.25 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
- 6-22
- 27-45
- 51-76
- 88-108
- 146-169
|
Protein Sequence
|
>Arylamine N-acetyltransferase 1
MDIDAYFERIGYKNSRDKLDLETLTDILQHQIRAIPFENLNIHCGEAMELDLEVIFDQIV
RRKRGGWCLQVNHLLYWALTMIGFETTILGGYVYNTFNDKYSSAMIHLLLKVTIDGRDYI
ADAGFGRSYQMWQPLELISGKYQPQTPCIFRLTEDRGTWYLDQIRREQYIPNQDFLDSDL
LEKNEYRKIYSFTLEPRTIKDFESVNTYLQESPASVFTSKSFCSLQTPEGVHCLVGFTLT
YRRFNYKDNTDLVEFKTLNEKEIEENLKNIFNISLEKKLTPKHGDKFFTI
|
External Links |
GenBank ID Protein
| ABF57403.1 |
UniProtKB/Swiss-Prot ID
| Q1JPA6 |
UniProtKB/Swiss-Prot Entry Name
| ARY1_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BT025447 |
GeneCard ID
| NAT1 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |