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| Identification |
|---|
| BMDB Protein ID
| BMDBP00360 |
| Secondary Accession Numbers
| None |
| Name
| Arylamine N-acetyltransferase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| NAT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Participates in the detoxification of a plethora of hydrazine and arylamine drugs. |
| Pathways
|
Not Available
|
| Reactions
|
| Paraxanthine + Acetyl-CoA → 5-Acetylamino-6-formylamino-3-methyluracil + Coenzyme A |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 27 |
| Locus
| Not Available |
| SNPs
| NAT1 |
| Gene Sequence
|
>873 bp
ATGGACATTGACGCATATTTTGAAAGAATTGGTTATAAGAACTCGAGGGACAAATTGGAC
TTGGAAACATTAACTGACATTCTTCAGCATCAGATCCGAGCCATTCCCTTTGAGAACCTT
AACATCCACTGTGGGGAAGCCATGGAATTGGACTTAGAGGTCATTTTTGATCAAATTGTG
AGGAGGAAACGGGGTGGGTGGTGTCTCCAAGTCAACCACCTTCTGTACTGGGCCCTGACC
ATGATCGGTTTTGAGACCACCATACTGGGAGGGTATGTGTACAACACATTCAACGACAAA
TACAGCAGCGCCATGATCCACCTCCTGCTGAAGGTGACCATCGACGGCAGGGACTACATA
GCTGATGCTGGGTTTGGGCGCTCTTACCAGATGTGGCAGCCTCTCGAGTTAATTTCTGGG
AAGTACCAGCCCCAGACGCCTTGCATCTTCCGCTTGACTGAAGACAGAGGAACCTGGTAC
CTGGACCAAATCAGAAGAGAGCAGTACATCCCAAACCAAGACTTTCTGGATTCTGACCTC
TTGGAAAAGAATGAGTATCGGAAAATCTACTCTTTTACTCTTGAACCTCGAACAATTAAA
GACTTTGAGTCTGTGAATACATACCTTCAAGAGTCTCCAGCATCTGTGTTTACAAGCAAG
TCATTTTGCTCCTTGCAGACCCCAGAAGGTGTTCATTGCTTAGTGGGTTTCACCCTCACC
TACAGGAGATTCAATTATAAGGACAATACAGATTTGGTAGAGTTTAAGACACTGAATGAG
AAAGAAATAGAAGAAAATCTAAAAAACATATTTAATATTTCCTTGGAGAAAAAGCTTACC
CCCAAACATGGTGATAAATTTTTTACCATTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 290 |
| Molecular Weight
| 34199.0 |
| Theoretical pI
| 5.25 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 6-22
- 27-45
- 51-76
- 88-108
- 146-169
|
| Protein Sequence
|
>Arylamine N-acetyltransferase 1
MDIDAYFERIGYKNSRDKLDLETLTDILQHQIRAIPFENLNIHCGEAMELDLEVIFDQIV
RRKRGGWCLQVNHLLYWALTMIGFETTILGGYVYNTFNDKYSSAMIHLLLKVTIDGRDYI
ADAGFGRSYQMWQPLELISGKYQPQTPCIFRLTEDRGTWYLDQIRREQYIPNQDFLDSDL
LEKNEYRKIYSFTLEPRTIKDFESVNTYLQESPASVFTSKSFCSLQTPEGVHCLVGFTLT
YRRFNYKDNTDLVEFKTLNEKEIEENLKNIFNISLEKKLTPKHGDKFFTI
|
| External Links |
|---|
| GenBank ID Protein
| ABF57403.1 |
| UniProtKB/Swiss-Prot ID
| Q1JPA6 |
| UniProtKB/Swiss-Prot Entry Name
| ARY1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT025447 |
| GeneCard ID
| NAT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
