Identification
BMDB Protein ID BMDBP00360
Secondary Accession Numbers None
Name Arylamine N-acetyltransferase 1
Synonyms Not Available
Gene Name NAT1
Protein Type Enzyme
Biological Properties
General Function Secondary metabolites biosynthesis, transport and catabolism
Specific Function Participates in the detoxification of a plethora of hydrazine and arylamine drugs.
Pathways Not Available
Reactions
Paraxanthine + Acetyl-CoA → 5-Acetylamino-6-formylamino-3-methyluracil + Coenzyme A details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 27
Locus Not Available
SNPs NAT1
Gene Sequence
>873 bp
ATGGACATTGACGCATATTTTGAAAGAATTGGTTATAAGAACTCGAGGGACAAATTGGAC
TTGGAAACATTAACTGACATTCTTCAGCATCAGATCCGAGCCATTCCCTTTGAGAACCTT
AACATCCACTGTGGGGAAGCCATGGAATTGGACTTAGAGGTCATTTTTGATCAAATTGTG
AGGAGGAAACGGGGTGGGTGGTGTCTCCAAGTCAACCACCTTCTGTACTGGGCCCTGACC
ATGATCGGTTTTGAGACCACCATACTGGGAGGGTATGTGTACAACACATTCAACGACAAA
TACAGCAGCGCCATGATCCACCTCCTGCTGAAGGTGACCATCGACGGCAGGGACTACATA
GCTGATGCTGGGTTTGGGCGCTCTTACCAGATGTGGCAGCCTCTCGAGTTAATTTCTGGG
AAGTACCAGCCCCAGACGCCTTGCATCTTCCGCTTGACTGAAGACAGAGGAACCTGGTAC
CTGGACCAAATCAGAAGAGAGCAGTACATCCCAAACCAAGACTTTCTGGATTCTGACCTC
TTGGAAAAGAATGAGTATCGGAAAATCTACTCTTTTACTCTTGAACCTCGAACAATTAAA
GACTTTGAGTCTGTGAATACATACCTTCAAGAGTCTCCAGCATCTGTGTTTACAAGCAAG
TCATTTTGCTCCTTGCAGACCCCAGAAGGTGTTCATTGCTTAGTGGGTTTCACCCTCACC
TACAGGAGATTCAATTATAAGGACAATACAGATTTGGTAGAGTTTAAGACACTGAATGAG
AAAGAAATAGAAGAAAATCTAAAAAACATATTTAATATTTCCTTGGAGAAAAAGCTTACC
CCCAAACATGGTGATAAATTTTTTACCATTTAG
Protein Properties
Number of Residues 290
Molecular Weight 34199.0
Theoretical pI 5.25
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 6-22
  • 27-45
  • 51-76
  • 88-108
  • 146-169
Protein Sequence
>Arylamine N-acetyltransferase 1
MDIDAYFERIGYKNSRDKLDLETLTDILQHQIRAIPFENLNIHCGEAMELDLEVIFDQIV
RRKRGGWCLQVNHLLYWALTMIGFETTILGGYVYNTFNDKYSSAMIHLLLKVTIDGRDYI
ADAGFGRSYQMWQPLELISGKYQPQTPCIFRLTEDRGTWYLDQIRREQYIPNQDFLDSDL
LEKNEYRKIYSFTLEPRTIKDFESVNTYLQESPASVFTSKSFCSLQTPEGVHCLVGFTLT
YRRFNYKDNTDLVEFKTLNEKEIEENLKNIFNISLEKKLTPKHGDKFFTI
GenBank ID Protein ABF57403.1
UniProtKB/Swiss-Prot ID Q1JPA6
UniProtKB/Swiss-Prot Entry Name ARY1_BOVIN
PDB IDs Not Available
GenBank Gene ID BT025447
GeneCard ID NAT1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available