| Identification |
|---|
| BMDB Protein ID
| BMDBP00390 |
| Secondary Accession Numbers
| None |
| Name
| Cholinephosphotransferase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| CHPT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity). |
| Pathways
|
- Phosphatidylcholine Biosynthesis
- Phosphatidylcholine from phosphocholine: step 2/2
- Phospholipid Biosynthesis
- Phospholipid metabolism
- Plasmalogen Synthesis
|
| Reactions
|
| Citicoline → PC(16:0/16:0) + DG(16:0/16:0/0:0) |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| Not Available |
| SNPs
| CHPT1 |
| Gene Sequence
|
>1221 bp
ATGGCGGCGGGCGCCGGGGCCAGGCCGGCGCCGCGCTGGCTGAAGGCGCTGACCGAGCCG
CTGAGCGCGGCGCAGCTGCGGCGGCTGGAGGAGCACCGCTACACCGCGGCGGGCGTCTCG
CTGCTCGAGCCGCCGCTGCAGCTCTACTGGACCTGGCTGCTCCAGTGGATCCCGCTGTGG
ATGGCCCCCAACTCCATCACCCTCCTGGGCCTCGCCATCAACATGCTCACCACGCTCGTG
CTCATCTCCTATTGCCCCACGGTCACCGAGGAGGCACCATACTGGACATACCTTTTATGT
GCATTAGGACTCTTCATCTACCAGTCACTGGATGCTATTGATGGGAAACAAGCCAGAAGG
ACAAATTCTTGTTCTCCTTTAGGGGAACTTTTTGACCATGGTTGCGACTCTCTTTCCACA
GTTTTTATGGCAGTTGGAGCTTCAATTGCTGTTCGCTTAGGAACTCACCCCGACTGGTTG
TTTTTCTGCTCTTTTATTGGGATGTTCATGTTTTATTGTGCTCACTGGCAGACTTATGTT
TCAGGCGTGTTGAGGTTTGGAAAAGTGGATGTAACTGAAATTCAGATAGCTTTAGTGATC
GTCTTCGTGTTATCTACATTTGGAGGAGCAACAATGTGGGACTACACGATACCCATCCTA
GAAATAAAATTGAAGATCTTACCAGTTCTTGGAGTAGTAGGTGGAGCAATATTTTCCTGT
TCAAATTATTTCCATGTTATCCTCCATGGTGGTGTTGGCAAGAATGGATCCACTATAGCA
GGTACCAGTGTCTTATCACCTGGACTCCACATAGGAATAATTATTATACTGGCAATAATG
ATTTATAAAAAGTCAGCAACTAATTTGTTTGAAAAGCATCCTTGTCTTTATACCCTAATG
TTTGGATGTGTCTTTGCTAAAGTCTCACAGAAATTGGTGATAGCTCACATGACCAAAAGT
GAACTGTATCTTCAAGACACTGTCTTTATTGGCCCAGGTCTTTTATTTTTAGACCAGTAC
TTTAATAATTTTGTAGACGAATATATTGTTCTATGGATAGCAATGGTCATTTCTTCACTT
GATATGATGAGGTACTTTAGTGCTTTGTGCCTGCAAATTTCAAGACACCTTCATCTAAGT
ATCTTCAAGACTTCATGTCATCAAGCACCTGAACAGGTTCAAGTTCTTCCTCCAAAGAGT
CATCAGAATAACATGGATTGA
|
| Protein Properties |
|---|
| Number of Residues
| 406 |
| Molecular Weight
| 45249.0 |
| Theoretical pI
| 7.51 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 66-86
- 93-113
- 160-180
- 193-213
- 226-248
- 261-281
- 295-315
- 349-369
|
| Protein Sequence
|
>Cholinephosphotransferase 1
MAAGAGARPAPRWLKALTEPLSAAQLRRLEEHRYTAAGVSLLEPPLQLYWTWLLQWIPLW
MAPNSITLLGLAINMLTTLVLISYCPTVTEEAPYWTYLLCALGLFIYQSLDAIDGKQARR
TNSCSPLGELFDHGCDSLSTVFMAVGASIAVRLGTHPDWLFFCSFIGMFMFYCAHWQTYV
SGVLRFGKVDVTEIQIALVIVFVLSTFGGATMWDYTIPILEIKLKILPVLGVVGGAIFSC
SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGIIIILAIMIYKKSATNLFEKHPCLYTLM
FGCVFAKVSQKLVIAHMTKSELYLQDTVFIGPGLLFLDQYFNNFVDEYIVLWIAMVISSL
DMMRYFSALCLQISRHLHLSIFKTSCHQAPEQVQVLPPKSHQNNMD
|
| External Links |
|---|
| GenBank ID Protein
| AAI16047.1 |
| UniProtKB/Swiss-Prot ID
| Q1LZE6 |
| UniProtKB/Swiss-Prot Entry Name
| CHPT1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC116046 |
| GeneCard ID
| CHPT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
