| Identification |
|---|
| BMDB Protein ID
| BMDBP00432 |
| Secondary Accession Numbers
| None |
| Name
| GMP reductase 2 |
| Synonyms
|
Not Available
|
| Gene Name
| GMPR2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (Probable). Plays a role in modulating cellular differentiation (By similarity). |
| Pathways
|
|
| Reactions
|
| Inosinic acid + Ammonia + NADP → Guanosine monophosphate + NADPH |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| Not Available |
| SNPs
| GMPR2 |
| Gene Sequence
|
>1047 bp
ATGCCTCACATCGACAACGACGTCAAACTGGATTTCAAGGATGTCCTGTTGAGGCCCAAA
CGCAGTACCCTTAAGTCTCGAAGTGAGGTGGATCTCACAAGATCCTTTGCCTTTCGGAAC
TCAAAGCAGATGTACACTGGGATCCCCATTATTGCTGCCAATATGGATACTGTGGGCACC
TTTGAGATGGCCAAGGTCCTCTGTAAGTTCTCCCTCTTCACTGCTGTCCATAAACACTAC
AGCCTCGAGCAGTGGAAAGAGTTTGCCAGCCAGAATCCTGACTGTCTTGAGCATCTGGCT
GCCAGCTCAGGCACAGGCTCTTCGGACTTTGAGCAGCTGGAACAGATCCTGAACGCTATT
CCCCAGGTGAAGTATGTATGCCTGGACGTGGCCAATGGCTACTCTGAACACTTTGTGGAA
TTTGTGAAGGATGTGCGGAAGCGCTTCCCTGAACACACCATCATGGCAGGGAATGTGGTA
ACAGGAGAAATGGTGGAAGAGCTGATCCTCTCTGGGGCTGACATCATCAAAGTGGGAATT
GGACCAGGCTCCGTGTGTACCACCCGGAAGAAAACTGGAGTGGGGTATCCACAGCTAAGT
GCAGTGATGGAGTGTGCAGATGCTGCTCACGGCCTCAAAGGCCACATCATTTCAGATGGA
GGCTGCAGCTGTCCTGGGGATGTGGCCAAGGCTTTCGGGGCAGGGGCTGACTTCGTGATG
CTGGGCGGCATGCTGGCTGGGCACAGTGAGTCAGGTGGTGAGCTCATCGAGAGGAATGGC
AGGAAGTACAAGCTCTTCTACGGCATGAGTTCCGAAATGGCCATGAAGAAGTATGCCGGG
GGTGTGGCTGAGTACAGGGCCTCAGAAGGAAAGACAGTGGAGGTGCCCTTTAAAGGGGAT
GTGGAACATACCATCCGAGACATTATTGGAGGCATCCGCTCCACCTGCACTTACGTGGGA
GCAGCTAAGCAGAAGGAGCTGAGCCGGAGAACTACCTTCATCCGTGTCACCCAGCAGGTG
AAACCGATCTTCAGTGACGAGAGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 348 |
| Molecular Weight
| 38033.0 |
| Theoretical pI
| 7.52 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>GMP reductase 2
MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFAFRNSKQMYTGIPIIAANMDTVGT
FEMAKVLCKFSLFTAVHKHYSLEQWKEFASQNPDCLEHLAASSGTGSSDFEQLEQILNAI
PQVKYVCLDVANGYSEHFVEFVKDVRKRFPEHTIMAGNVVTGEMVEELILSGADIIKVGI
GPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM
LGGMLAGHSESGGELIERNGRKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGD
VEHTIRDIIGGIRSTCTYVGAAKQKELSRRTTFIRVTQQVKPIFSDES
|
| External Links |
|---|
| GenBank ID Protein
| AAI09696.1 |
| UniProtKB/Swiss-Prot ID
| Q32L93 |
| UniProtKB/Swiss-Prot Entry Name
| GMPR2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109695 |
| GeneCard ID
| GMPR2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
