Showing Protein Alkaline phosphatase, tissue-nonspecific isozyme (BMDBP00463)
| Identification | |||
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| BMDB Protein ID | BMDBP00463 | ||
| Secondary Accession Numbers |
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| Name | Alkaline phosphatase, tissue-nonspecific isozyme | ||
| Synonyms | Not Available | ||
| Gene Name | ALPL | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Inorganic ion transport and metabolism | ||
| Specific Function | This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi). | ||
| Pathways | Not Available | ||
| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 2 | ||
| Locus | Not Available | ||
| SNPs | ALPL | ||
| Gene Sequence |
>1575 bp ATGATTTCACCATTCTTACTGCTGGCTATCGGTACCTGTTTTGCCAGCTCCTTAGTGCCA GAGAAAGAGAAAGATCCCAAGTACTGGCGAGACCAAGCTCAGCAGACCCTGAAAAATGCC CTGAGGCTTCAGACTCTCAACACCAACGTGGCTAAGAACGTCATCATGTTCCTGGGAGAC GGTATGGGCGTGTCCACCGTGACAGCTGCCCGCATCCTCAAGGGGCAGCTCCACCACAGC CCTGGGGAGGAGACCAAGCTGGAGATGGACAAGTTTCCCTACGTGGCCCTCTCCAAGACG TACAACACCAACGCCCAGGTCCCTGATAGCGCAGGCACCGCCACCGCCTACTTGTGTGGG GTGAAGGCCAATGAGGGCACCGTGGGGGTGAGCGCAGCAACCCAGCGCTCCCAGTGTAAC ACCACTCAGGGCAACGAGGTGACCTCCATCCTGCGCTGGGCCAAGGACGCAGGGAAATCC GTGGGCATCGTGACCACCACGCGCGTGAACCACGCCACCCCCAGCGCCTCCTACGCCCAC TCTGCTGACCGGGACTGGTACTCGGACAACGAGATGCCCCCGGAGGCCCTGAGCCAGGGC TGCAAGGACATCGCCTACCAGCTCATGTACAACATTAAGGACATCGAGGTGATCATGGGC GGCGGCCGGAAGTACATGTTCCCCAAGAACAGAACCGATGTGGAGTATGAGCTGGATGAG AAGGCCAGAGGCACGAGGCTGGACGGCCTGAACCTCATCGACATCTGGAAGAGCTTCAAA CCGAAACACAAGCACTCTCACTATGTCTGGAACCGCACTGATCTCCTGGCCCTTGACCCC CACAGCGTGGACTACCTCTTGGGTCTCTTTGAGCCGGGGGACATGCAGTACGAACTCAAC AGGAACAATGCGACTGACCCTTCACTCTCTGAGATGGTAGAGATGGCCATCAGGATCCTG AACAAGAACCCCAAAGGCTTCTTCCTGCTGGTGGAAGGGGGCAGGATTGACCACGGGCAC CACGAGGGCAAAGCCAAGCAGGCACTGCACGAGGCGGTGGAGATGGACCAGGCCATCGGG CAGGCAGGTGCTATGACCTCCGTAGAAGACACACTGACCGTTGTCACCGCTGACCACTCC CACGTCTTTACCTTTGGCGGGTACACCCCCCGTGGCAACTCGATCTTTGGTCTGGCCCCC ATGGTGAGTGACACAGACAAGAAGCCGTTCACCGCCATCCTGTACGGCAACGGGCCTGGC TACAAGGTGGTGGGTGGTGAGCGAGAGAATGTCTCCATGGTGGACTACGCTCACAATAAC TACCAGGCGCAGTCCGCGGTGCCCCTGCGCCACGAGACCCACGGCGGCGAGGACGTGGCC GTCTTTGCCAAGGGCCCCATGGCGCACCTGCTGCACGGCGTCCAAGAGCAGAACTACATC CCCCACGTGATGGCCTACGCAGCCTGCATTGGTGCCAACCGCGACCACTGTGCCTCAGCC AGCTCGTCCGGCAGCCCCTCCCCCGGCCCCCTGCTGCTCCTCCTGGCCCTGCTGCCCCTG GGCAGCCTGTTCTGA |
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| Protein Properties | |||
| Number of Residues | 524 | ||
| Molecular Weight | 57193.0 | ||
| Theoretical pI | 6.77 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>Alkaline phosphatase, tissue-nonspecific isozyme MISPFLLLAIGTCFASSLVPEKEKDPKYWRDQAQQTLKNALRLQTLNTNVAKNVIMFLGD GMGVSTVTAARILKGQLHHSPGEETKLEMDKFPYVALSKTYNTNAQVPDSAGTATAYLCG VKANEGTVGVSAATQRSQCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSASYAH SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIEVIMGGGRKYMFPKNRTDVEYELDE KARGTRLDGLNLIDIWKSFKPKHKHSHYVWNRTDLLALDPHSVDYLLGLFEPGDMQYELN RNNATDPSLSEMVEMAIRILNKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIG QAGAMTSVEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPG YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYI PHVMAYAACIGANRDHCASASSSGSPSPGPLLLLLALLPLGSLF |
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| External Links | |||
| GenBank ID Protein | AAA30380.1 | ||
| UniProtKB/Swiss-Prot ID | P09487 | ||
| UniProtKB/Swiss-Prot Entry Name | PPBT_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | M18443 | ||
| GeneCard ID | ALPL | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||