| Identification |
|---|
| BMDB Protein ID
| BMDBP00623 |
| Secondary Accession Numbers
| None |
| Name
| Methylmalonyl-CoA mutase, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| MMUT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. |
| Pathways
|
- Propanoate Metabolism
- Threonine and 2-Oxobutanoate Degradation
- Valine, Leucine, and Isoleucine Degradation
|
| Reactions
|
| R-Methylmalonyl-CoA → Succinyl-CoA |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 23 |
| Locus
| Not Available |
| SNPs
| MMUT |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 750 |
| Molecular Weight
| 83235.0 |
| Theoretical pI
| 7.02 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Methylmalonyl-CoA mutase, mitochondrial
MLRAKNQLFLLSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLI
WHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESN
KFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRLRGDVGMAGVAIDTVEDTKILFDGIPLE
KMSVSMTMNGAVIPVLATFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMK
IIADIFQYTAKHMPKFNSISISGYHMQEAGADAILELAYTIADGLEYCRTGLQAGLTIDE
FAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMLQPKNSKSLLLRAHCQTSGWSLTE
QDPYNNIIRTTIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPK
VADPWGGSYMMESLTNDIYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARID
SGSEVIVGVNKYQLEKEESVDVLAIDNTSVRNKQIEKLKKVKSSRDQALAERCLDALTAC
AASGDGNILALAVDATRARCTVGEITYAMKKVFGEHKANDRMVSGAYRQEFGESKEIAFA
IKRVEKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQ
AVDADVHTVGVSTLAAGHKTLVPELIKELNALGRPDILVMCGGVIPPQDYEFLFEVGVSN
VFGPGTRIPKAAVQVLDDIEKCLEKKQQSI
|
| External Links |
|---|
| GenBank ID Protein
| CAC17595.1 |
| UniProtKB/Swiss-Prot ID
| Q9GK13 |
| UniProtKB/Swiss-Prot Entry Name
| MUTA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ300476 |
| GeneCard ID
| MMUT |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
