Showing Protein Thiamin pyrophosphokinase 1 (BMDBP01075)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 6 metabolites
Identification
BMDB Protein ID BMDBP01075
Secondary Accession Numbers
  • BMDBP03069
Name Thiamin pyrophosphokinase 1
Synonyms Not Available
Gene Name TPK1
Protein Type Enzyme
Biological Properties
General Function Coenzyme transport and metabolism
Specific Function Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate (By similarity).
Pathways
  • Cofactor biosynthesis
  • Thiamine diphosphate biosynthesis
  • Thiamine diphosphate from thiamine: step 1/1
Reactions
Adenosine triphosphate + Thiamine → Adenosine monophosphate + Thiamine pyrophosphate details
Adenosine triphosphate + Thiamine pyrophosphate → ADP + Thiamin triphosphate details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 4
Locus Not Available
SNPs TPK1
Gene Sequence 
>732 bp
ATGGAGCATGCCATTACCCCGCTGGACCCCCTGCTTCCCTCTGGGAGTTTGAAATACTGC
CTTGTGATTCTGAACCAGCCTTTGGACAAATGTTTTCGTCATCTTTGGCACAAAGCTCTT
TTAAGAGCCTGTGCTGATGGAGGTGCCAACCACTTATATGACGTCACAGAAGGAGAGAGG
GAGAGCTTTCTGCCTGAATTCATCAGTGGAGACTTTGATTCTATTAGGCCTGAAGTTAGA
GAACACTACGCTATTAAGGGCTGTGAAATTATTTCAACTCCTGATCAAGACCATACTGAT
TTTACCAAGTGCCTTGAAGTGCTCCAAAAGAAGATAGAAGAAAAAGACCTACAGGTAGAT
ATGATCGTGACCTTGGGAGGACTTGCTGGACGCTTTGACCAGATCATGGCATCTGTGAGC
ACTTTGTTCCAAGCGCCTCAAATAACTTCTTTGCCAGTTATAATAATCCAAGAGGAATCT
CTCATCTACCTGCTCCAACCGGGAAAGCACAAATTGCATGTAGATACCGGGATGGAAGGT
GATTGGTGTGGCCTCATTCCTGTTGGACAGCCTTGCAATCAGGTGACCACAACAGGCCTA
AAGTGGAACCTTACACATCAGATGCTTGGCTTTGGAACACTAGTCAGCACGTCCAACACC
TACGACGGATCTGGTGTTGTGACTGTAGAGACGGACCATCCCCTGCTCTGGACCATGGCC
ATAAAAAACTGA
Protein Properties
Number of Residues 243
Molecular Weight 27028.0
Theoretical pI 4.94
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence 
>Thiamin pyrophosphokinase 1
MEHAITPLDPLLPSGSLKYCLVILNQPLDKCFRHLWHKALLRACADGGANHLYDVTEGER
ESFLPEFISGDFDSIRPEVREHYAIKGCEIISTPDQDHTDFTKCLEVLQKKIEEKDLQVD
MIVTLGGLAGRFDQIMASVSTLFQAPQITSLPVIIIQEESLIYLLQPGKHKLHVDTGMEG
DWCGLIPVGQPCNQVTTTGLKWNLTHQMLGFGTLVSTSNTYDGSGVVTVETDHPLLWTMA
IKN
GenBank ID Protein AAX08853.1
UniProtKB/Swiss-Prot ID Q5E9T4
UniProtKB/Swiss-Prot Entry Name TPK1_BOVIN
PDB IDs
GenBank Gene ID BT020836
GeneCard ID TPK1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available