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Identification |
BMDB Protein ID
| BMDBP01076 |
Secondary Accession Numbers
| |
Name
| Pyruvate dehydrogenase E1 component subunit beta, mitochondrial |
Synonyms
|
Not Available
|
Gene Name
| PDHB |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Energy production and conversion |
Specific Function
| The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. |
Pathways
|
Not Available
|
Reactions
|
Pyruvic acid + Coenzyme A + NAD → Acetyl-CoA + Carbon dioxide + NADH |
details
|
Pyruvic acid + Lipoamide → S-Acetyldihydrolipoamide-E + Carbon dioxide |
details
|
Pyruvic acid → Acetyl-CoA |
details
|
|
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 22 |
Locus
| Not Available |
SNPs
| PDHB |
Gene Sequence
|
>612 bp
ATGGCGGTGGTTGCTGTGTTGGTGCGGAAACCCCTTGAGCAGGTCTCCGGGCTGCTGAGG
AGGCGGTTCCACCGGACCGCGCCGGCTGCACTGCAGGTGACAGTTCGTGAGGCTATAAAT
CAAGGCATGGATGAGGAGCTGGAAAGAGATGAGAAGGTATTTCTCCTTGGGGAAGAAGTT
GCCCAGTACGATGGGGCATATAAGGTTAGTCGAGGCCTGTGGAAGAAATATGGAGATAAG
AGGATCATAGATACTCCCATATCTGAGATGGGCTTTGCTGGAATTGCTGTAGGTGCCGCT
ATGGCTGGGTTACGGCCCATTTGTGAATTCATGACCTTCAATTTCTCTATGCAAGCCATC
GACCAGGTCATAAACTCAGCTGCCAAGACGTACTACATGTCAGGGGGCCTTCAGTCTGTG
CCCATAGTCTTCAGGGGGCCCAATGGCGCCTCAGCAGGTGTAGCTGCCCAGCACTCACAG
TGTTTTGCTGCCTGGTATGGGCATTGCCCAGGCTTAAAGGTGGTCAGCCCCTGGAGTTCA
GAGGATGCAAAAGGGCTTATTAAATCAGCCATTCGGGATAACAACCCAGTGGTGGTGCTG
AGAATGAATTGA
|
Protein Properties |
Number of Residues
| 359 |
Molecular Weight
| 39126.0 |
Theoretical pI
| 6.63 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
MAVVAVLVRKPLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQSVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWSS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFELPSEAQSKDFLIPIGKAKIERQGTHVTIV
AHSRPVGHCLEAATVLSKEGIECEVINLRTIRPMDIETIEGSVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
|
External Links |
GenBank ID Protein
| AAX46758.1 |
UniProtKB/Swiss-Prot ID
| P11966 |
UniProtKB/Swiss-Prot Entry Name
| ODPB_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BT021911 |
GeneCard ID
| PDHB |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |