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Identification
BMDB Protein ID BMDBP02835
Secondary Accession Numbers
  • BMDBP03097
Name 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha
Synonyms Not Available
Gene Name AGPAT1
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Pathways Not Available
Reactions
1-Acyl-sn-glycerol 3-phosphate + Long-chain fatty acyl-CoA → Coenzyme A + 1,2-Diacyl-sn-glycerol 3-phosphate details
LPA(16:0/0:0) + Palmityl-CoA → Coenzyme A + PA(16:0/16:0) details
LPA(16:0/0:0) + Stearoyl-CoA → Coenzyme A + PA(16:0/18:0) details
LPA(16:0/0:0) + Oleoyl-CoA → Coenzyme A + PA(16:0/18:1(9Z)) details
LPA(16:0/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(16:0/18:3(6Z,9Z,12Z)) details
LPA(16:0/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(16:0/20:0) details
LPA(16:0/0:0) + Gondoyl-CoA → Coenzyme A + PA(16:0/20:1(11Z)) details
LPA(16:0/0:0) + Docosanoyl-CoA → Coenzyme A + PA(16:0/22:0) details
LPA(16:0/0:0) + Erucoyl-CoA → Coenzyme A + PA(16:0/22:1(13Z)) details
LPA(18:0/0:0) + Stearoyl-CoA → Coenzyme A + PA(18:0/18:0) details
LPA(18:0/0:0) + Oleoyl-CoA → Coenzyme A + PA(18:0/18:1(9Z)) details
LPA(18:0/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(18:0/18:3(6Z,9Z,12Z)) details
LPA(18:0/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:0/20:0) details
LPA(18:0/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:0/20:1(11Z)) details
LPA(18:0/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:0/22:0) details
LPA(18:0/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:0/22:1(13Z)) details
LysoPA(18:1(11Z)/0:0) + Oleoyl-CoA → Coenzyme A + PA(18:1(11Z)/18:1(9Z)) details
LysoPA(18:1(11Z)/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(18:1(11Z)/18:3(6Z,9Z,12Z)) details
LysoPA(18:1(11Z)/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:1(11Z)/20:0) details
LysoPA(18:1(11Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:1(11Z)/20:1(11Z)) details
LysoPA(18:1(11Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:1(11Z)/22:0) details
LysoPA(18:1(11Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:1(11Z)/22:1(13Z)) details
LysoPA(18:1(9Z)/0:0) + Oleoyl-CoA → Coenzyme A + PA(18:1(9Z)/18:1(9Z)) details
LysoPA(18:1(9Z)/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(18:1(9Z)/18:3(6Z,9Z,12Z)) details
LysoPA(18:1(9Z)/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:1(9Z)/20:0) details
LysoPA(18:1(9Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:1(9Z)/20:1(11Z)) details
LysoPA(18:1(9Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:1(9Z)/22:0) details
LysoPA(18:1(9Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:1(9Z)/22:1(13Z)) details
LysoPA(18:2(9Z,12Z)/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)) details
LysoPA(18:2(9Z,12Z)/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:2(9Z,12Z)/20:0) details
LysoPA(18:2(9Z,12Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:2(9Z,12Z)/20:1(11Z)) details
LysoPA(18:2(9Z,12Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:2(9Z,12Z)/22:0) details
LysoPA(18:2(9Z,12Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:2(9Z,12Z)/22:1(13Z)) details
LysoPA(18:3(6Z,9Z,12Z)/0:0) + Gamma-linolenoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)) details
LysoPA(18:3(6Z,9Z,12Z)/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/20:0) details
LysoPA(18:3(6Z,9Z,12Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/20:1(11Z)) details
LysoPA(18:3(6Z,9Z,12Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/22:0) details
LysoPA(18:3(6Z,9Z,12Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:3(6Z,9Z,12Z)/22:1(13Z)) details
LysoPA(18:3(9Z,12Z,15Z)/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(18:3(9Z,12Z,15Z)/20:0) details
LysoPA(18:3(9Z,12Z,15Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(18:3(9Z,12Z,15Z)/20:1(11Z)) details
LysoPA(18:3(9Z,12Z,15Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(18:3(9Z,12Z,15Z)/22:0) details
LysoPA(18:3(9Z,12Z,15Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(18:3(9Z,12Z,15Z)/22:1(13Z)) details
LysoPA(20:0/0:0) + Eicosanoyl-CoA → Coenzyme A + PA(20:0/20:0) details
LysoPA(20:0/0:0) + Gondoyl-CoA → Coenzyme A + PA(20:0/20:1(11Z)) details
LysoPA(20:0/0:0) + Docosanoyl-CoA → Coenzyme A + PA(20:0/22:0) details
LysoPA(20:0/0:0) + Erucoyl-CoA → Coenzyme A + PA(20:0/22:1(13Z)) details
LysoPA(20:1(11Z)/0:0) + Gondoyl-CoA → Coenzyme A + PA(20:1(11Z)/20:1(11Z)) details
LysoPA(20:1(11Z)/0:0) + Docosanoyl-CoA → Coenzyme A + PA(20:1(11Z)/22:0) details
LysoPA(20:1(11Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(20:1(11Z)/22:1(13Z)) details
LysoPA(22:0/0:0) + Docosanoyl-CoA → Coenzyme A + PA(22:0/22:0) details
LysoPA(22:0/0:0) + Erucoyl-CoA → Coenzyme A + PA(22:0/22:1(13Z)) details
LysoPA(22:1(13Z)/0:0) + Erucoyl-CoA → Coenzyme A + PA(22:1(13Z)/22:1(13Z)) details
LPA(16:0/0:0) → PA(16:0/16:0) details
Palmityl-CoA + LPA(16:0/0:0) → PA(16:0/16:0) + Coenzyme A details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 23
Locus Not Available
SNPs AGPAT1
Gene Sequence Not Available
Protein Properties
Number of Residues 287
Molecular Weight 32005.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • 1-26
Transmembrane Regions
  • 38-58
  • 128-148
Protein Sequence Not Available
GenBank ID Protein AAK69168.1
UniProtKB/Swiss-Prot ID Q95JH2
UniProtKB/Swiss-Prot Entry Name PLCA_BOVIN
PDB IDs Not Available
GenBank Gene ID AF281677
GeneCard ID AGPAT1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available