Showing Protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (BMDBP03188)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 6 metabolites
Identification
BMDB Protein ID BMDBP03188
Secondary Accession Numbers
  • BMDBP02893
Name Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Synonyms Not Available
Gene Name ENPP3
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Hydrolase that metabolizes extracellular nucleotides, including ATP, GTP, UTP and CTP (By similarity). Limits mast cell and basophil responses during inflammation and during the chronic phases of allergic responses by eliminating the extracellular ATP that functions as signaling molecule and activates basophils and mast cells and induces the release of inflammatory cytokines. Metabolizes extracellular ATP in the lumen of the small intestine, and thereby prevents ATP-induced apoptosis of intestinal plasmacytoid dendritic cells (By similarity). Has also alkaline phosphodiesterase activity (By similarity).
Pathways Not Available
Reactions
Dephospho-CoA + Water → Pantetheine 4'-phosphate + Adenosine monophosphate details
FAD + Water → Adenosine monophosphate + Flavin Mononucleotide details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 9
Locus Not Available
SNPs ENPP3
Gene Sequence Not Available
Protein Properties
Number of Residues 874
Molecular Weight 99523.0
Theoretical pI Not Available
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 12-30
Protein Sequence Not Available
GenBank ID Protein AAI22743.1
UniProtKB/Swiss-Prot ID P15396
UniProtKB/Swiss-Prot Entry Name ENPP3_BOVIN
PDB IDs Not Available
GenBank Gene ID BC122742
GeneCard ID ENPP3
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available