Showing metabocard for Adenine (BMDB0000034)

General function:

Nucleotide transport and metabolism

Specific function:

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.

Gene Name:

APRT

Uniprot ID:

Q56JW4

Molecular weight:

19537.0

Reactions

General function:

Amino acid transport and metabolism

Specific function:

Not Available

Gene Name:

DDO

Uniprot ID:

P31228

Molecular weight:

37660.0

General function:

Nucleotide transport and metabolism

Specific function:

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

Gene Name:

PNP

Uniprot ID:

P55859

Molecular weight:

32037.0

Reactions

General function:

Involved in purinergic nucleotide receptor activity, G-

Specific function:

Receptor for extracellular adenine nucleotides such as ADP (PubMed:7626079). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (By similarity).

Gene Name:

P2RY1

Uniprot ID:

P48042

Molecular weight:

42288.0

General function:

Involved in binding

Specific function:

Not Available

Gene Name:

SLC25A4

Uniprot ID:

Q3ZC05

Molecular weight:

32898.0