Showing metabocard for Stearoyl-CoA (BMDB0001114)

General function:

Lipid transport and metabolism

Specific function:

Not Available

Gene Name:

GNPAT

Uniprot ID:

A4IF87

Molecular weight:

77664.0

Reactions

General function:

Involved in carnitine O-palmitoyltransferase activity

Specific function:

Not Available

Gene Name:

CPT1B

Uniprot ID:

Q58DK1

Molecular weight:

88512.0

Reactions

General function:

Involved in carnitine O-palmitoyltransferase activity

Specific function:

Not Available

Gene Name:

CPT2

Uniprot ID:

Q2KJB7

Molecular weight:

74483.0

Reactions

General function:

Energy production and conversion

Specific function:

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).

Gene Name:

SCD

Uniprot ID:

Q9TT94

Molecular weight:

41705.0

General function:

Energy production and conversion

Specific function:

Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids.

Gene Name:

SCD5

Uniprot ID:

Q2KIA4

Molecular weight:

38215.0

General function:

Lipid transport and metabolism

Specific function:

Catalyzes the conversion of fatty acids such as long-chain and very long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.

Gene Name:

ACSBG1

Uniprot ID:

Q2KHW5

Molecular weight:

80585.0

Reactions

General function:

Not Available

Specific function:

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. In liver, plays a role in esterifying exogenous fatty acids to glycerol.

Gene Name:

DGAT1

Uniprot ID:

Q8MK44

Molecular weight:

55602.0

Reactions