Showing Protein Hydroxymethylglutaryl-CoA synthase, mitochondrial (BMDBP00359)
| Identification | |||
|---|---|---|---|
| BMDB Protein ID | BMDBP00359 | ||
| Secondary Accession Numbers | None | ||
| Name | Hydroxymethylglutaryl-CoA synthase, mitochondrial | ||
| Synonyms | Not Available | ||
| Gene Name | HMGCS2 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Lipid transport and metabolism | ||
| Specific Function | This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | ||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 3 | ||
| Locus | Not Available | ||
| SNPs | HMGCS2 | ||
| Gene Sequence |
>1527 bp ATGCAGCGGCTGTTGACTCCAGTGAGGCAGGTGTTGCAAGTGAAGAGAGTGATGCAAGAA GCTTCCCTCCTGCCTGCCCGCCTTCTCCCAGCAGCCCACCCCAGTTTTTCTACAGTTCCG GCTGTCCCCTTGGCCAAAACAGATACTTGGCCAAAGGATGTGGGTATTCTTGCCATGGAG GTCTACTTTCCAGCCCAATATGTGGACCAAACAGAGCTGGAGAAGTTTAACAAAGTGGAG GCAGGGAGGTACACCGTGGGCTTGGGCCAGACCCAGATGGGCTTCTGCTCAGTCCAGGAG GATGTCAACTCCCTGTGCCTGACGGTGGTGCAACAGCTGATGGAGCGCACGCAGCTCCCC TGGGACTCTGTGGGCCGCCTGGAAGTGGGCACTGAGACCATCATCGATAAGTCCAAGGCT GTCAAAACAGTGCTTATGGAGCTCTTCCAGGATTCAGGCAACACTGACATTGAGGGCATA GATACCACCAATGCCTGCTACGGTGGCACTGCCTCCCTCTTCAATGCTGCCAACTGGATG GAATCCAGCTCCTGGGATGGTCGCTATGCACTGGTGGTCTGTGGGGACATCGCAGTCTAC CCCAGTGGTAACGCTCGCCCCACAGGCGGGGCTGGAGCTGTGGCAATGCTGGTTGGGCCT GAGGCCCCTCTGGTCCTCGAGAGAGGGCTTAGAGGAACCCACATGGAGAATGTGTACGAC TTCTACAAACCAGATGTGACTTCAGAGTACCCACTGGTGGATGGGAAGCTCTCCATCCAG TGCTACTTACGGGCCCTGGACAAATGCTATGCATTCTACCGTCAAAAGATCGAGAAACAG TGGAAGCAAGCTGGCATCGATCGGCCTTTCACTCTCGATGATGTGCAGTATATGATTTTT CACACGCCTTTCTGCAAGTTAGTCCAGAAATCCCTGGCCCGCCTGATGTTCAATGACTTC CTGTTGGCCAGTGGTGACACACAGACTGGCATCTACAAGGGCTTGGAGGCCTTCAGGGGA CTAAAGCTGGAAGACACCTACACCAATAAGGATGTAGATAAAGCATTTCTAAAAGCCTCT CTGAACATGTTCAATAAGAAAACCAAGAACTCCCTCTACCTCTCCACGTACAACGGGAAT ATGTACACCTCATCCCTATATGGATGCCTGGCCTCACTTCTGGCCCATCACTCTGCCCAA GACTTGGCTGGCTCCAGGATCGGTGCCTTCTCTTATGGCTCTGGTTTGGCAGCAAGTTTC TTTTCTTTCCGGGTGTCCCAGGATGCTTCTCCAGGCTCCCCACTGGAGAAGCTGGTATCC AGTACATCAGACCTGCAGAAACGTCTTGCCTCCCGGAAGCGTGTGTCTCCTGAGGAGTTC ACAGAAATAATGAACCAAAGAGAACAATACTACCACAAGATGAATTTCTCACCACCTGGT GATAAGAACAGCCTTTTCCCAGGCACTTGGTACCTGGAGCGAGTGGATGAGCTGTATCGC AGGAAGTACGCCCGGCGTCCCGTTTAA |
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| Protein Properties | |||
| Number of Residues | 508 | ||
| Molecular Weight | 56895.0 | ||
| Theoretical pI | 8.16 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Hydroxymethylglutaryl-CoA synthase, mitochondrial MQRLLTPVRQVLQVKRVMQEASLLPARLLPAAHPSFSTVPAVPLAKTDTWPKDVGILAME VYFPAQYVDQTELEKFNKVEAGRYTVGLGQTQMGFCSVQEDVNSLCLTVVQQLMERTQLP WDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM ESSSWDGRYALVVCGDIAVYPSGNARPTGGAGAVAMLVGPEAPLVLERGLRGTHMENVYD FYKPDVTSEYPLVDGKLSIQCYLRALDKCYAFYRQKIEKQWKQAGIDRPFTLDDVQYMIF HTPFCKLVQKSLARLMFNDFLLASGDTQTGIYKGLEAFRGLKLEDTYTNKDVDKAFLKAS LNMFNKKTKNSLYLSTYNGNMYTSSLYGCLASLLAHHSAQDLAGSRIGAFSYGSGLAASF FSFRVSQDASPGSPLEKLVSSTSDLQKRLASRKRVSPEEFTEIMNQREQYYHKMNFSPPG DKNSLFPGTWYLERVDELYRRKYARRPV |
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| External Links | |||
| GenBank ID Protein | AAI12667.1 | ||
| UniProtKB/Swiss-Prot ID | Q2KIE6 | ||
| UniProtKB/Swiss-Prot Entry Name | HMCS2_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | BC112666 | ||
| GeneCard ID | HMGCS2 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||