Showing metabocard for Guanosine (BMDB0000133)

General function:

Involved in 5'-nucleotidase activity

Specific function:

May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.

Gene Name:

NT5C2

Uniprot ID:

O46411

Molecular weight:

64841.0

Reactions

General function:

Nucleotide transport and metabolism

Specific function:

Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.

Gene Name:

NT5E

Uniprot ID:

Q05927

Molecular weight:

62966.0

General function:

Nucleotide transport and metabolism

Specific function:

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

Gene Name:

PNP

Uniprot ID:

P55859

Molecular weight:

32037.0

Reactions

General function:

Transcription

Specific function:

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Gene Name:

POLR1B

Uniprot ID:

A6QLS0

Molecular weight:

128397.0

General function:

Nucleotide transport and metabolism

Specific function:

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Gene Name:

RRM1

Uniprot ID:

Q32LP1

Molecular weight:

90019.0

General function:

Transcription

Specific function:

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Gene Name:

POLR2B

Uniprot ID:

A5PJW8

Molecular weight:

133867.0

General function:

Transcription

Specific function:

Not Available

Gene Name:

rpB2

Uniprot ID:

B2WTN5

Molecular weight:

5508.0