Showing metabocard for Taurine (BMDB0000251)

General function:

Amino acid transport and metabolism

Specific function:

Catalyzes the production of GABA.

Gene Name:

GAD1

Uniprot ID:

Q0VCA1

Molecular weight:

66784.0

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General function:

Amino acid transport and metabolism

Specific function:

Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is L-aspartate. Does not exhibit any decarboxylation activity toward glutamate.

Gene Name:

GADL1

Uniprot ID:

A6QM00

Molecular weight:

59380.0

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General function:

Involved in chloride ion binding

Specific function:

Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Channel opening is also triggered by taurine and beta-alanine. Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (By similarity). Plays an important role in the down-regulation of neuronal excitability (PubMed:11178872). Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).

Gene Name:

GLRA1

Uniprot ID:

P57695

Molecular weight:

52614.0

General function:

Involved in taurine:sodium symporter activity

Specific function:

Sodium-dependent taurine and beta-alanine transporter.

Gene Name:

SLC6A6

Uniprot ID:

Q9MZ34

Molecular weight:

69751.0

General function:

Not Available

Specific function:

Cleaves glutathione conjugates.

Gene Name:

GGT6

Uniprot ID:

A7YWM1

Molecular weight:

49626.0

Reactions