Record Information |
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Version | 1.0 |
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Creation Date | 2016-09-30 23:46:21 UTC |
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Update Date | 2020-06-04 19:20:09 UTC |
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BMDB ID | BMDB0007883 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | PC(14:0/20:4(5Z,8Z,11Z,14Z)) |
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Description | PC(14:0/20:4(5Z,8Z,11Z,14Z)), also known as phosphatidylcholine(14:0/20:4) or gpcho(14:0/20:4), belongs to the class of organic compounds known as phosphatidylcholines. These are glycerophosphocholines in which the two free -OH are attached to one fatty acid each through an ester linkage. Thus, PC(14:0/20:4(5Z,8Z,11Z,14Z)) is considered to be a glycerophosphocholine lipid molecule. PC(14:0/20:4(5Z,8Z,11Z,14Z)) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. PC(14:0/20:4(5Z,8Z,11Z,14Z)) exists in all eukaryotes, ranging from yeast to humans. PC(14:0/20:4(5Z,8Z,11Z,14Z)) participates in a number of enzymatic reactions, within cattle. In particular, S-Adenosylhomocysteine and PC(14:0/20:4(5Z,8Z,11Z,14Z)) can be biosynthesized from S-adenosylmethionine and pe-nme2(14:0/20:4(5Z,8Z,11Z,14Z)) through its interaction with the enzyme phosphatidylethanolamine N-methyltransferase. Furthermore, Cytidine monophosphate and PC(14:0/20:4(5Z,8Z,11Z,14Z)) can be biosynthesized from CDP-choline and DG(14:0/20:4(5Z,8Z,11Z,14Z)/0:0) through its interaction with the enzyme choline/ethanolaminephosphotransferase. Finally, PC(14:0/20:4(5Z,8Z,11Z,14Z)) and L-serine can be converted into choline and PS(14:0/20:4(5Z,8Z,11Z,14Z)); which is mediated by the enzyme phosphatidylserine synthase. In cattle, PC(14:0/20:4(5Z,8Z,11Z,14Z)) is involved in a couple of metabolic pathways, which include phosphatidylcholine biosynthesis PC(14:0/20:4(5Z,8Z,11Z,14Z)) pathway and phosphatidylethanolamine biosynthesis pe(14:0/20:4(5Z,8Z,11Z,14Z)) pathway. |
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Structure | |
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Synonyms | Value | Source |
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1-Myristoyl-2-arachidonoyl-sn-glycero-3-phosphocholine | ChEBI | 1-Tetradecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine | ChEBI | GPCho(14:0/20:4) | ChEBI | GPCho(14:0/20:4n6) | ChEBI | GPCho(14:0/20:4W6) | ChEBI | PC(14:0/20:4) | ChEBI | PC(14:0/20:4n6) | ChEBI | PC(14:0/20:4W6) | ChEBI | Phosphatidylcholine(14:0/20:4) | ChEBI | Phosphatidylcholine(14:0/20:4n6) | ChEBI | Phosphatidylcholine(14:0/20:4W6) | ChEBI | GPCho(34:4) | HMDB | PC(34:4) | HMDB | Lecithin | HMDB | Phosphatidylcholine(34:4) | HMDB | PC(14:0/20:4(5Z,8Z,11Z,14Z)) | Lipid Annotator |
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Chemical Formula | C42H76NO8P |
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Average Molecular Weight | 754.0285 |
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Monoisotopic Molecular Weight | 753.530854925 |
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IUPAC Name | Not Available |
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Traditional Name | Not Available |
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CAS Registry Number | Not Available |
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SMILES | Not Available |
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InChI Identifier | InChI=1S/C42H76NO8P/c1-6-8-10-12-14-16-18-19-20-21-22-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-17-15-13-11-9-7-2/h14,16,19-20,22-23,27,29,40H,6-13,15,17-18,21,24-26,28,30-39H2,1-5H3/b16-14-,20-19-,23-22-,29-27-/t40-/m1/s1 |
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InChI Key | SRQSAJRUMDQMMS-NLDJLLEISA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as phosphatidylcholines. These are glycerophosphocholines in which the two free -OH are attached to one fatty acid each through an ester linkage. |
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Kingdom | Organic compounds |
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Super Class | Lipids and lipid-like molecules |
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Class | Glycerophospholipids |
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Sub Class | Glycerophosphocholines |
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Direct Parent | Phosphatidylcholines |
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Alternative Parents | |
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Substituents | - Diacylglycero-3-phosphocholine
- Phosphocholine
- Fatty acid ester
- Dialkyl phosphate
- Dicarboxylic acid or derivatives
- Organic phosphoric acid derivative
- Phosphoric acid ester
- Alkyl phosphate
- Fatty acyl
- Quaternary ammonium salt
- Tetraalkylammonium salt
- Carboxylic acid ester
- Carboxylic acid derivative
- Organic oxygen compound
- Organic nitrogen compound
- Carbonyl group
- Organooxygen compound
- Organonitrogen compound
- Organic oxide
- Organopnictogen compound
- Amine
- Organic salt
- Hydrocarbon derivative
- Aliphatic acyclic compound
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Molecular Framework | Aliphatic acyclic compounds |
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External Descriptors | |
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Ontology |
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Status | Detected and Quantified |
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Origin | |
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Biofunction | Not Available |
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Application | Not Available |
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Cellular locations | - Cell membrane
- Intracellular membrane
- Membrane
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Physical Properties |
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State | Solid |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | Not Available |
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Spectra |
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Spectra | |
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