Showing metabocard for 1,3-Diaminopropane (BMDB0000002)

General function:

Secondary metabolites biosynthesis, transport and catabolism

Specific function:

Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity).

Gene Name:

AOC3

Uniprot ID:

Q9TTK6

Molecular weight:

84500.0

Reactions

General function:

Posttranslational modification, protein turnover, chaperones

Specific function:

Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a critical lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. This is the first step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.

Gene Name:

DHPS

Uniprot ID:

Q6EWQ6

Molecular weight:

41029.0