Showing metabocard for CDP (BMDB0001546)

General function:

Lipid transport and metabolism

Specific function:

Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.

Gene Name:

PGS1

Uniprot ID:

Q2KJ28

Molecular weight:

62732.0

General function:

Lipid transport and metabolism

Specific function:

Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol (By similarity). Exhibits specificity for the nature of the acyl chains at the sn-1 and sn-2 positions in the substrate, PA and the preferred acyl chain composition is 1-stearoyl-2-arachidonoyl-sn-phosphatidic acid (By similarity). Plays an important role in regulating the growth and maturation of lipid droplets which are storage organelles at the center of lipid and energy homeostasis (By similarity).

Gene Name:

CDS2

Uniprot ID:

A0JNC1

Molecular weight:

51357.0

General function:

Involved in ADP-ribose diphosphatase activity

Specific function:

Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress (By similarity).

Gene Name:

ADPRM

Uniprot ID:

A7YY53

Molecular weight:

39235.0

General function:

Lipid transport and metabolism

Specific function:

Catalyzes phosphatidylcholine biosynthesis from CDP-choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity).

Gene Name:

CHPT1

Uniprot ID:

Q1LZE6

Molecular weight:

45249.0

General function:

Involved in ethanolaminephosphotransferase activity

Specific function:

Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the foramtion of phosphatidylethanolamine via 'Kennedy' pathway (By similarity).

Gene Name:

SELENOI

Uniprot ID:

Q17QM4

Molecular weight:

45214.0

General function:

Cell wall/membrane/envelope biogenesis

Specific function:

Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine (By similarity).

Gene Name:

PCYT2

Uniprot ID:

Q5EA75

Molecular weight:

44158.0

General function:

Lipid transport and metabolism

Specific function:

Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.

Gene Name:

DOLK

Uniprot ID:

Q58CR4

Molecular weight:

59190.0

General function:

Nucleotide transport and metabolism

Specific function:

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).

Gene Name:

NME7

Uniprot ID:

Q5E9Y9

Molecular weight:

42599.0

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

CANT1

Uniprot ID:

E1BGL5

Molecular weight:

44706.0

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

CMPK2

Uniprot ID:

F1N2W6

Molecular weight:

64396.0

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

RRM2

Uniprot ID:

E1BI58

Molecular weight:

44821.0

Reactions