Showing metabocard for Chitin (BMDB0003362)

General function:

Involved in alpha-tubulin binding

Specific function:

The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

Gene Name:

B4GALT1

Uniprot ID:

P08037

Molecular weight:

44843.0

General function:

Involved in beta-N-acetylglucosaminylglycopeptide beta-

Specific function:

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

Gene Name:

B4GALT3

Uniprot ID:

Q5EA87

Molecular weight:

44371.0

General function:

Involved in alpha-1,3-mannosylglycoprotein 2-beta-N-ace

Specific function:

Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.

Gene Name:

POMGNT1

Uniprot ID:

Q5EAB6

Molecular weight:

75077.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

Not Available

Uniprot ID:

Q6B411

Molecular weight:

16783.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

LYZ3

Uniprot ID:

Q06284

Molecular weight:

16317.0

General function:

Involved in lysozyme activity

Specific function:

May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6 (By similarity).

Gene Name:

LYZL6

Uniprot ID:

Q29RT1

Molecular weight:

16559.0

General function:

Involved in cation binding

Specific function:

Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding (By similarity).

Gene Name:

CHIA

Uniprot ID:

Q95M17

Molecular weight:

52129.0

Reactions

General function:

Carbohydrate transport and metabolism

Specific function:

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Also has ManNAc kinase activity (By similarity).

Gene Name:

NAGK

Uniprot ID:

Q3SZM9

Molecular weight:

37268.0

Reactions

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

LYS

Uniprot ID:

P80189

Molecular weight:

16476.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

Not Available

Uniprot ID:

Q6B410

Molecular weight:

16391.0

General function:

Involved in N-acetylglucosamine-1-phosphodiester alpha-

Specific function:

Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P-mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N-acetylglucosaminyltransferases.

Gene Name:

NAGPA

Uniprot ID:

P68827

Molecular weight:

57223.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

LYZ1

Uniprot ID:

Q06285

Molecular weight:

16279.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

Not Available

Uniprot ID:

Q27996

Molecular weight:

15929.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

LYZ1

Uniprot ID:

P04421

Molecular weight:

16373.0

General function:

Involved in lysozyme activity

Specific function:

Not Available

Gene Name:

LYZL1

Uniprot ID:

A0JNM6

Molecular weight:

16779.0

General function:

Involved in lysozyme activity

Specific function:

Not Available

Gene Name:

SPACA5

Uniprot ID:

Q32PD6

Molecular weight:

17580.0

General function:

Involved in lysozyme activity

Specific function:

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Gene Name:

LYZ2

Uniprot ID:

Q06283

Molecular weight:

16304.0