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Record Information |
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Version | 1.0 |
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Creation Date | 2016-09-30 22:20:32 UTC |
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Update Date | 2020-06-04 20:56:16 UTC |
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BMDB ID | BMDB0000175 |
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Secondary Accession Numbers | |
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Metabolite Identification |
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Common Name | Inosinic acid |
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Description | Inosinic acid, also known as 5'-inosinate or 5'-imp, belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached. Inosinic acid is possibly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Inosinic acid exists in all living species, ranging from bacteria to humans. |
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Structure | |
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Synonyms | Value | Source |
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2'-Inosine-5'-monophosphate | ChEBI | 5'-IMP | ChEBI | 5'-Inosinate | ChEBI | 5'-Inosine monophosphate | ChEBI | 5'-Inosinic acid | ChEBI | Hypoxanthosine 5'-monophosphate | ChEBI | Inosine 5'-monophosphate | ChEBI | Inosine 5'-phosphate | ChEBI | Inosine monophosphate | ChEBI | Ribosylhypoxanthine monophosphate | ChEBI | 2'-Inosine-5'-monophosphoric acid | Generator | 5'-Inosine monophosphoric acid | Generator | Hypoxanthosine 5'-monophosphoric acid | Generator | Inosine 5'-monophosphoric acid | Generator | Inosine 5'-phosphoric acid | Generator | Inosine monophosphoric acid | Generator | Ribosylhypoxanthine monophosphoric acid | Generator | Inosinate | Generator | IMP | HMDB | Inosine-5'-monophosphate | HMDB | Inosinic acids | HMDB | Inosinate, sodium | HMDB | monoPhosphate, inosine | HMDB | monoPhosphate, ribosylhypoxanthine | HMDB | Sodium inosinate | HMDB | Acid, inosinic | HMDB | Acids, inosinic | HMDB |
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Chemical Formula | C10H13N4O8P |
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Average Molecular Weight | 348.206 |
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Monoisotopic Molecular Weight | 348.047099924 |
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IUPAC Name | Not Available |
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Traditional Name | Not Available |
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CAS Registry Number | 131-99-7 |
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SMILES | Not Available |
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InChI Identifier | InChI=1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 |
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InChI Key | GRSZFWQUAKGDAV-KQYNXXCUSA-N |
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Chemical Taxonomy |
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Description | belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached. |
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Kingdom | Organic compounds |
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Super Class | Nucleosides, nucleotides, and analogues |
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Class | Purine nucleotides |
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Sub Class | Purine ribonucleotides |
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Direct Parent | Purine ribonucleoside monophosphates |
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Alternative Parents | |
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Substituents | - Purine ribonucleoside monophosphate
- Pentose phosphate
- Pentose-5-phosphate
- Glycosyl compound
- N-glycosyl compound
- 6-oxopurine
- Hypoxanthine
- Monosaccharide phosphate
- Pentose monosaccharide
- Imidazopyrimidine
- Purine
- Pyrimidone
- Monoalkyl phosphate
- Alkyl phosphate
- Pyrimidine
- Phosphoric acid ester
- Organic phosphoric acid derivative
- N-substituted imidazole
- Monosaccharide
- Tetrahydrofuran
- Vinylogous amide
- Azole
- Imidazole
- Heteroaromatic compound
- Secondary alcohol
- 1,2-diol
- Lactam
- Organoheterocyclic compound
- Azacycle
- Oxacycle
- Alcohol
- Organic oxide
- Organopnictogen compound
- Organic oxygen compound
- Organic nitrogen compound
- Organooxygen compound
- Organonitrogen compound
- Hydrocarbon derivative
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | |
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Ontology |
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Status | Detected and Quantified |
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Origin | |
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Biofunction | Not Available |
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Application | Not Available |
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Cellular locations | |
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Physical Properties |
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State | Solid |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | LogP | Not Available | Not Available |
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Predicted Properties | Not Available |
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Spectra |
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Spectra | |
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Biological Properties |
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Cellular Locations | |
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Biospecimen Locations | - All Tissues
- Liver
- Longissimus Thoracis Muscle
- Milk
- Muscle
- Semimembranosus Muscle
- Testis
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Pathways | |
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Normal Concentrations |
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All Tissues | Expected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Liver | Detected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Liver | Detected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Liver | Detected and Quantified | 34 +/- 27 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Longissimus Thoracis Muscle | Detected and Quantified | 15 +/- 11 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Milk | Detected but not Quantified | Not Quantified | Not Specified | Not Specified | Normal | | details | Muscle | Detected and Quantified | 40-8977 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Muscle | Detected and Quantified | 460 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Muscle | Detected and Quantified | 31-59 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Semimembranosus Muscle | Detected and Quantified | 124 +/- 136 nmol/g of tissue | Not Specified | Not Specified | Normal | | details | Testis | Detected and Quantified | 97 +/- 19 nmol/g of tissue | Not Specified | Not Specified | Normal | | details |
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Abnormal Concentrations |
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| Not Available |
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External Links |
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HMDB ID | HMDB0000175 |
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DrugBank ID | DB04566 |
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Phenol Explorer Compound ID | Not Available |
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FooDB ID | FDB021901 |
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KNApSAcK ID | C00007224 |
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Chemspider ID | 8264 |
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KEGG Compound ID | C00130 |
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BioCyc ID | IMP |
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BiGG ID | 33960 |
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Wikipedia Link | Inosinic_acid |
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METLIN ID | 5196 |
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PubChem Compound | 8582 |
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PDB ID | Not Available |
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ChEBI ID | 17202 |
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References |
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Synthesis Reference | Park, Yeong Hun; Cho, Gwang Myeong; Baek, Min Ji; Hong, Guk Gi; Lee, Jin Nam. Method for preparing 5'-inosinic acid by using microbe capable of over-expressing purC gene. Repub. Korea (2007), 7pp. |
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Material Safety Data Sheet (MSDS) | Not Available |
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General References | - Melzer N, Wittenburg D, Hartwig S, Jakubowski S, Kesting U, Willmitzer L, Lisec J, Reinsch N, Repsilber D: Investigating associations between milk metabolite profiles and milk traits of Holstein cows. J Dairy Sci. 2013 Mar;96(3):1521-34. doi: 10.3168/jds.2012-5743. [PubMed:23438684 ]
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