Showing metabocard for Hydrogen peroxide (BMDB0003125)

General function:

Inorganic ion transport and metabolism

Specific function:

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.

Gene Name:

CAT

Uniprot ID:

P00432

Molecular weight:

59915.0

Reactions

General function:

Involved in electron carrier activity

Specific function:

Not Available

Gene Name:

SUOX

Uniprot ID:

Q3MHX0

Molecular weight:

60501.0

Reactions

General function:

Involved in calcium ion binding

Specific function:

Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May protect the udder from infection and promote growth in newborn calves. Inhibits growth of the following bacterial species: E.coli, K.pneumoniae, P.aeruginosa, S.sonnei, S.saphrophyticus, S.epidermidis, and S.dysenteriae.

Gene Name:

LPO

Uniprot ID:

P80025

Molecular weight:

80642.0

General function:

Secondary metabolites biosynthesis, transport and catabolism

Specific function:

Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity (By similarity).

Gene Name:

AOC3

Uniprot ID:

Q9TTK6

Molecular weight:

84500.0

Reactions

General function:

Coenzyme transport and metabolism

Specific function:

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

Gene Name:

PNPO

Uniprot ID:

Q5E9K3

Molecular weight:

30366.0

Reactions

General function:

Involved in oxygen-dependent protoporphyrinogen oxidase

Specific function:

Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.

Gene Name:

PPOX

Uniprot ID:

P56602

Molecular weight:

50612.0

Reactions

General function:

Posttranslational modification, protein turnover, chaperones

Specific function:

Protects the hemoglobin in erythrocytes from oxidative breakdown.

Gene Name:

GPX1

Uniprot ID:

P00435

Molecular weight:

22659.0

Reactions

General function:

Inorganic ion transport and metabolism

Specific function:

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Gene Name:

SOD1

Uniprot ID:

P00442

Molecular weight:

15683.0

General function:

Amino acid transport and metabolism

Specific function:

Not Available

Gene Name:

DDO

Uniprot ID:

P31228

Molecular weight:

37660.0

Reactions

General function:

Involved in copper ion binding

Specific function:

Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin.

Gene Name:

TYRP1

Uniprot ID:

Q8WN57

Molecular weight:

60617.0

Reactions

General function:

Nucleotide transport and metabolism

Specific function:

Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide, N-methylphthalazinium and phthalazine, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.

Gene Name:

AOX1

Uniprot ID:

P48034

Molecular weight:

147611.0

Reactions

General function:

Amino acid transport and metabolism

Specific function:

Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

Gene Name:

MAOA

Uniprot ID:

P21398

Molecular weight:

59758.0

Reactions

General function:

Not Available

Specific function:

Not Available

Gene Name:

IL4I1

Uniprot ID:

F1N191

Molecular weight:

64479.0

Reactions